DNA repair and oxidative stress defense systems in radiation-resistant Deinococcus murrayi

Structural and DNA end resection study of the bacterial NurA-HerA complex

(2023) Jieyu Yang et al.   BMC BIOLOGY

Structural and functional insights into the activation of the dual incision activity of UvrC, a key player in bacterial NER

(2023) Anna Seck et al.   NUCLEIC ACIDS RESEARCH

Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans

(2023) Andriko von Kügelgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small-Molecule Mn Antioxidants in Caenorhabditis elegans and Deinococcus radiodurans Supplant MnSOD Enzymes during Aging and Irradiation

(2022) Elena K. Gaidamakova et al.   mBio

In vitro reconstitution of an efficient nucleotide excision repair system using mesophilic enzymes from Deinococcus radiodurans

(2022) Anna Seck et al.   Communications Biology

DR0022 from Deinococcus radiodurans is an Acid Uracil‐DNA Glycosylase

(2022) Jing Li et al.   FEBS Journal

ColabFold: making protein folding accessible to all

(2022) Milot Mirdita et al.   NATURE METHODS

Thiol Reductases in Deinococcus Bacteria and Roles in Stress Tolerance

(2022) Arjan de Groot et al.   Antioxidants

Disentangling Unusual Catalytic Properties and the Role of the [4Fe-4S] Cluster of Three Endonuclease III from the Extremophile D. radiodurans

(2022) Filipe Rollo et al.   MOLECULES

Structural and functional characterization of DdrC, a novel DNA damage-induced nucleoid associated protein involved in DNA compaction

(2022) Anne-Sophie Banneville et al.   NUCLEIC ACIDS RESEARCH

A multidomain connector links the outer membrane and cell wall in phylogenetically deep-branching bacteria

(2022) Andriko von Kügelgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PNPase and RhlB Interact and Reduce the Cellular Availability of Oxidized RNA in Deinococcus radiodurans

(2022) Runhua Han et al.   Microbiology Spectrum

Biochemical and Structural Study of RuvC and YqgF from Deinococcus radiodurans

(2022) Yiyang Sun et al.   mBio

The SDBC is active in quenching oxidative conditions and bridges the cell envelope layers in Deinococcus radiodurans

(2022) Domenica Farci et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UniProt: the Universal Protein Knowledgebase in 2023

(2022) et al.   NUCLEIC ACIDS RESEARCH

PprI: The Key Protein in Response to DNA Damage in Deinococcus

(2021) Huizhi Lu et al.   Frontiers in Cell and Developmental Biology

New insights into the activation of Radiation Desiccation Response regulon in Deinococcus radiodurans

(2021) Anaganti Narasimha et al.   JOURNAL OF BIOSCIENCES

Redox signaling through zinc activates the radiation response in Deinococcus bacteria

(2021) Romaric Magerand et al.   Scientific Reports

Effects of Conserved Wedge Domain Residues on DNA Binding Activity of Deinococcus radiodurans RecG Helicase

(2021) Sun-Wook Jeong et al.   Frontiers in Genetics

An in vivo Interaction Network of DNA-Repair Proteins: A Snapshot at Double Strand Break Repair in Deinococcus radiodurans

(2021) Aman Kumar Ujaoney et al.   JOURNAL OF PROTEOME RESEARCH

Coexistence of SOS-Dependent and SOS-Independent Regulation of DNA Repair Genes in Radiation-Resistant Deinococcus Bacteria

(2021) Laurence Blanchard et al.   Cells

PprA Protein Inhibits DNA Strand Exchange and ATP Hydrolysis of Deinococcus RecA and Regulates the Recombination in Gamma-Irradiated Cells

(2021) Yogendra Singh Rajpurohit et al.   Frontiers in Cell and Developmental Biology

Characterization of the DdrD protein from the extremely radioresistant bacterium Deinococcus radiodurans

(2021) Claire Bouthier de la Tour et al.   EXTREMOPHILES

Highly accurate protein structure prediction with AlphaFold

(2021) John Jumper et al.   NATURE

A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation

(2021) Jordan K. Villa et al.   Scientific Reports

Atypical Bacilliredoxin AbxC Plays a Role in Responding to Oxidative Stress in Radiation-Resistant Bacterium Deinococcus radiodurans

(2021) Soyoung Jeong et al.   Antioxidants

Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses

(2021) Nicolas Eugénie et al.   Cells

DASH-type cryptochromes – solved and open questions

(2020) Stephan Kiontke et al.   BIOLOGICAL CHEMISTRY

Structural and Functional Characterization of a Unique AP Endonuclease From Deinococcus radiodurans

(2020) Yuan He et al.   Frontiers in Microbiology

Participation of RecJ in the base excision repair pathway of Deinococcus radiodurans

(2020) Kaiying Cheng et al.   NUCLEIC ACIDS RESEARCH

SMART: recent updates, new developments and status in 2020

(2020) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Topoisomerase IB interacts with genome segregation proteins and is involved in multipartite genome maintenance in Deinococcus radiodurans

(2020) Swathi Kota et al.   MICROBIOLOGICAL RESEARCH

The three Endonuclease III variants of Deinococcus radiodurans possess distinct and complementary DNA repair activities

(2019) Aili Sarre et al.   DNA REPAIR

BamA is a pivotal protein in cell envelope synthesis and cell division in Deinococcus radiodurans

(2019) Jiangliu Yu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO

(2019) Huizhi Lu et al.   NUCLEIC ACIDS RESEARCH

Analysis of 1,000 Type-Strain Genomes Improves Taxonomic Classification of Bacteroidetes

(2019) Marina García-López et al.   Frontiers in Microbiology

Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus

(2019) Arjan de Groot et al.   NUCLEIC ACIDS RESEARCH

CDD/SPARCLE: the conserved domain database in 2020

(2019) Shennan Lu et al.   NUCLEIC ACIDS RESEARCH

drFrnE Represents a Hitherto Unknown Class of Eubacterial Cytoplasmic Disulfide Oxido-Reductases

(2018) Subhash C. Bihani et al.   ANTIOXIDANTS & REDOX SIGNALING

The absence of the RecN protein suppresses the cellular defects of Deinococcus radiodurans irradiated cells devoid of the PprA protein by limiting recombinational repair of DNA lesions

(2018) Alice Devigne et al.   DNA REPAIR

1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life

(2017) Supratim Mukherjee et al.   NATURE BIOTECHNOLOGY

Oxidative stress, protein damage and repair in bacteria

(2017) Benjamin Ezraty et al.   NATURE REVIEWS MICROBIOLOGY

Conservation and diversity of the IrrE/DdrO-controlled radiation response in radiation-resistant Deinococcus bacteria

(2017) Laurence Blanchard et al.   MicrobiologyOpen

Functional and evolutionary characterization of Ohr proteins in eukaryotes reveals many active homologs among pathogenic fungi

(2017) D.A. Meireles et al.   Redox Biology

A tamB homolog is involved in maintenance of cell envelope integrity and stress resistance of Deinococcus radiodurans

(2017) Jiangliu Yu et al.   Scientific Reports

Untargeted metabolite profiling reveals that nitric oxide bioynthesis is an endogenous modulator of carotenoid biosynthesis in Deinococcus radiodurans and is required for extreme ionizing radiation resistance

(2016) Alex Hansler et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Protein splicing of a recombinase intein induced by ssDNA and DNA damage

(2016) Christopher W. Lennon et al.   GENES & DEVELOPMENT

The S-layer Protein DR_2577 Binds Deinoxanthin and under Desiccation Conditions Protects against UV-Radiation in Deinococcus radiodurans

(2016) Domenica Farci et al.   Frontiers in Microbiology

A Decade of Biochemical and Structural Studies of the DNA Repair Machinery of Deinococcus radiodurans: Major Findings, Functional and Mechanistic Insight and Challenges

(2016) Joanna Timmins et al.   Computational and Structural Biotechnology Journal

CYP287A1 is a carotenoid 2-β-hydroxylase required for deinoxanthin biosynthesis in Deinococcus radiodurans R1

(2015) Zhengfu Zhou et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Surface (S)-layer proteins of Deinococcus radiodurans and their utility as vehicles for surface localization of functional proteins

(2015) Chitra Seetharam Misra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural and functional characterization of two unusual endonuclease III enzymes from Deinococcus radiodurans

(2015) Aili Sarre et al.   JOURNAL OF STRUCTURAL BIOLOGY

Intein Clustering Suggests Functional Importance in Different Domains of Life

(2015) Olga Novikova et al.   MOLECULAR BIOLOGY AND EVOLUTION

Repairing oxidized proteins in the bacterial envelope using respiratory chain electrons

(2015) Alexandra Gennaris et al.   NATURE

Protease Activity of PprI Facilitates DNA Damage Response: Mn(2+)-Dependence and Substrate Sequence-Specificity of the Proteolytic Reaction

(2015) Yunguang Wang et al.   PLoS One

Identification of New Genes Contributing to the Extreme Radioresistance of Deinococcus radiodurans Using a Tn5-Based Transposon Mutant Library

(2015) Rémi Dulermo et al.   PLoS One

Transcriptional Analysis of Deinococcus radiodurans Reveals Novel Small RNAs That Are Differentially Expressed under Ionizing Radiation

(2014) Chen-Hsun Tsai et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

RNA Sequencing and Proteogenomics Reveal the Importance of Leaderless mRNAs in the Radiation-Tolerant Bacterium Deinococcus deserti

(2014) Arjan de Groot et al.   Genome Biology and Evolution

Enigmatic Distribution, Evolution, and Function of Inteins

(2014) Olga Novikova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Radiation response inDeinococcus deserti: IrrE is a metalloprotease that cleaves repressor protein DdrO

(2014) Monika Ludanyi et al.   MOLECULAR MICROBIOLOGY

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Designing antioxidant peptides

(2014) Barbara S. Berlett et al.   REDOX REPORT

FrnE, a Cadmium-Inducible Protein in Deinococcus radiodurans, Is Characterized as a Disulfide Isomerase Chaperone In Vitro and for Its Role in Oxidative Stress Tolerance In Vivo

(2013) N. P. Khairnar et al.   JOURNAL OF BACTERIOLOGY

Genome Sequence and Transcriptome Analysis of the Radioresistant Bacterium Deinococcus gobiensis: Insights into the Extreme Environmental Adaptations

(2012) Menglong Yuan et al.   PLoS One

Death by protein damage in irradiated cells

(2011) Michael J. Daly   DNA REPAIR

The flexibility of UV-inducible mutation in Deinococcus ficus as evidenced by the existence of the imuB–dnaE2 gene cassette and generation of superior feather degrading bacteria

(2011) You-Hong Zeng et al.   MICROBIOLOGICAL RESEARCH

Oxidative Stress Resistance in Deinococcus radiodurans

(2011) D. Slade et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Gamma Radiation-induced Proteome ofDeinococcus radioduransPrimarily Targets DNA Repair and Oxidative Stress Alleviation

(2011) Bhakti Basu et al.   MOLECULAR & CELLULAR PROTEOMICS

DRA0336, another OxyR homolog, involved in the antioxidation mechanisms in Deinococcus radiodurans

(2010) Longfei Yin et al.   JOURNAL OF MICROBIOLOGY

Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans

(2010) Michael J. Daly et al.   PLoS One

Carotenoid biosynthesis in extremophilic Deinococcus–Thermus bacteria

(2010) Bing Tian et al.   TRENDS IN MICROBIOLOGY

Crystal Structure of the IrrE Protein, a Central Regulator of DNA Damage Repair in Deinococcaceae

(2009) Andreja Vujičić-Žagar et al.   JOURNAL OF MOLECULAR BIOLOGY

Mutagenic lesion bypass and two functionally different RecA proteins inDeinococcus deserti

(2009) Rémi Dulermo et al.   MOLECULAR MICROBIOLOGY

Alliance of Proteomics and Genomics to Unravel the Specificities of Sahara Bacterium Deinococcus deserti

(2009) Arjan de Groot et al.   PLoS Genetics

A Novel OxyR Sensor and Regulator of Hydrogen Peroxide Stress with One Cysteine Residue in Deinococcus radiodurans

(2008) Huan Chen et al.   PLoS One