PprI: The Key Protein in Response to DNA Damage in Deinococcus

Small Molecule Inhibitors Targeting the Key Proteins in DNA Damage Response for Cancer Therapy

(2020) Lulu Li et al.   CURRENT MEDICINAL CHEMISTRY

Physiology of Highly Radioresistant Escherichia coli After Experimental Evolution for 100 Cycles of Selection

(2020) Steven T. Bruckbauer et al.   Frontiers in Microbiology

Producing alcohol and salt stress tolerant strain of Saccharomyces cerevisiae by heterologous expression of pprI gene

(2019) S. Hossein Helalat et al.   ENZYME AND MICROBIAL TECHNOLOGY

DNA damage tolerance in stem cells, ageing, mutagenesis, disease and cancer therapy

(2019) Bas Pilzecker et al.   NUCLEIC ACIDS RESEARCH

Structure and DNA damage-dependent derepression mechanism for the XRE family member DG-DdrO

(2019) Huizhi Lu et al.   NUCLEIC ACIDS RESEARCH

Succinylome Analysis Reveals the Involvement of Lysine Succinylation in the Extreme Resistance of Deinococcus radiodurans

(2019) Congli Zhou et al.   PROTEOMICS

The diversity and commonalities of the radiation-resistance mechanisms of Deinococcus and its up-to-date applications

(2019) Mengmeng Jin et al.   AMB Express

Gene regulation for the extreme resistance to ionizing radiation of Deinococcus radiodurans

(2019) Wuzhou Wang et al.   GENE

Crystal structure of the transcriptional repressor DdrO: insight into the metalloprotease/repressor-controlled radiation response in Deinococcus

(2019) Arjan de Groot et al.   NUCLEIC ACIDS RESEARCH

Antioxidative system of Deinococcus radiodurans

(2019) Hui-zhou Qi et al.   RESEARCH IN MICROBIOLOGY

Enhancement of bioelectricity generation via heterologous expression of IrrE in Pseudomonas aeruginosa -inoculated MFCs

(2018) Jianmei Luo et al.   BIOSENSORS & BIOELECTRONICS

Across the tree of life, radiation resistance is governed by antioxidant Mn2+, gauged by paramagnetic resonance

(2017) Ajay Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Conservation and diversity of the IrrE/DdrO-controlled radiation response in radiation-resistant Deinococcus bacteria

(2017) Laurence Blanchard et al.   MicrobiologyOpen

Deinococcus radiodurans pprI expression enhances the radioresistance of eukaryotes

(2016) Ling Wen et al.   Oncotarget

Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans

(2016) Su Yang et al.   PLoS One

Global transcriptional analysis of Escherichia coli expressing IrrE, a regulator from Deinococcus radiodurans, in response to NaCl shock

(2015) Peng Zhao et al.   Molecular BioSystems

DdrO is an essential protein that regulates the radiation desiccation response and the apoptotic-like cell death in the radioresistantDeinococcus radioduransbacterium

(2015) Alice Devigne et al.   MOLECULAR MICROBIOLOGY

Expression of PprI from Deinococcus radiodurans Improves Lactic Acid Production and Stress Tolerance in Lactococcus lactis

(2015) Xiangrong Dong et al.   PLoS One

Protease Activity of PprI Facilitates DNA Damage Response: Mn(2+)-Dependence and Substrate Sequence-Specificity of the Proteolytic Reaction

(2015) Yunguang Wang et al.   PLoS One

Hsp20, a Small Heat Shock Protein of Deinococcus radiodurans, Confers Tolerance to Hydrogen Peroxide in Escherichia coli

(2014) Harinder Singh et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Radiation response inDeinococcus deserti: IrrE is a metalloprotease that cleaves repressor protein DdrO

(2014) Monika Ludanyi et al.   MOLECULAR MICROBIOLOGY

PprA Contributes to Deinococcus radiodurans Resistance to Nalidixic Acid, Genome Maintenance after DNA Damage and Interacts with Deinococcal Topoisomerases

(2014) Swathi Kota et al.   PLoS One

Extracellular dGMP Enhances Deinococcus radiodurans Tolerance to Oxidative Stress

(2013) Mingfeng Li et al.   PLoS One

DdrA, DdrD, and PprA: Components of UV and Mitomycin C Resistance in Deinococcus radiodurans R1

(2013) Kathiresan Selvam et al.   PLoS One

Comprehensive comparative-genomic analysis of Type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes

(2012) Kira S Makarova et al.   Biology Direct

Cooperation of PprI and DrRRA in response to extreme ionizing radiation in Deinococcus radiodurans

(2012) LiangYan Wang et al.   CHINESE SCIENCE BULLETIN

Significant Rewiring of the Transcriptome and Proteome of an Escherichia coli Strain Harboring a Tailored Exogenous Global Regulator IrrE

(2012) Tingjian Chen et al.   PLoS One

DNA binding is essential for PprI function in response to radiation damage in Deinococcus radiodurans

(2011) Huiming Lu et al.   DNA REPAIR

Oxidative Stress Resistance in Deinococcus radiodurans

(2011) D. Slade et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Genome-wide transcriptome and proteome analysis of Escherichia coli expressing IrrE, a global regulator of Deinococcus radiodurans

(2011) Zhengfu Zhou et al.   Molecular BioSystems

Interconversion between bound and free conformations of LexA orchestrates the bacterial SOS response

(2011) Matej Butala et al.   NUCLEIC ACIDS RESEARCH

Improved Osmotic Tolerance and Ethanol Production of Ethanologenic Escherichia coli by IrrE, a Global Regulator of Radiation-Resistance of Deinococcus radiodurans

(2010) Ruiqiang Ma et al.   CURRENT MICROBIOLOGY

Small-Molecule Antioxidant Proteome-Shields in Deinococcus radiodurans

(2010) Michael J. Daly et al.   PLoS One

Zinc Fingers as Biologic Redox Switches?

(2009) Klaus-D. Kröncke et al.   ANTIOXIDANTS & REDOX SIGNALING

Roles of PprA, IrrE, and RecA in the resistance of Deinococcus radiodurans to germicidal and environmentally relevant UV radiation

(2009) Anja Bauermeister et al.   ARCHIVES OF MICROBIOLOGY

Crystal Structure of the IrrE Protein, a Central Regulator of DNA Damage Repair in Deinococcaceae

(2009) Andreja Vujičić-Žagar et al.   JOURNAL OF MOLECULAR BIOLOGY

IrrE, a Global Regulator of Extreme Radiation Resistance in Deinococcus radiodurans, Enhances Salt Tolerance in Escherichia coli and Brassica napus

(2009) Jie Pan et al.   PLoS One

The bacterial LexA transcriptional repressor

(2008) M. Butala et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Deinococcus radiodurans: What Belongs to the Survival Kit?

(2008) Melanie Blasius et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Ku80 removal from DNA through double strand break–induced ubiquitylation

(2008) Lisa Postow et al.   JOURNAL OF CELL BIOLOGY

A Ligand-Induced Switch in the Periplasmic Domain of Sensor Histidine Kinase CitA

(2008) Madhumati Sevvana et al.   JOURNAL OF MOLECULAR BIOLOGY

Deinococcus radioduransPprI Switches on DNA Damage Response and Cellular Survival Networks after Radiation Damage

(2008) Huiming Lu et al.   MOLECULAR & CELLULAR PROTEOMICS

A conserved anti-repressor controls horizontal gene transfer by proteolysis

(2008) Baundauna Bose et al.   MOLECULAR MICROBIOLOGY

DrRRA: a novel response regulator essential for the extreme radioresistance of Deinococcus radiodurans

(2008) Liangyan Wang et al.   MOLECULAR MICROBIOLOGY

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH

A Novel OxyR Sensor and Regulator of Hydrogen Peroxide Stress with One Cysteine Residue in Deinococcus radiodurans

(2008) Huan Chen et al.   PLoS One