Design, Synthesis, and Evaluation of 18F-Labeling CYP1B1 PET Tracer Based on 2-Phenylquinazolin

Discovery of 4’-trifluoromethylchalcones as novel, potent and selective hCYP1B1 inhibitors without concomitant AhR activation

(2023) Yue Wu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis and In Vivo Fluorescence Imaging Study of a Cytochrome P450 1B1 Targeted NIR Probe Containing a Chelator Moiety

(2022) Zengtao Wang et al.   CHEMBIOCHEM

Medicinal Chemistry Strategies for the Development of Inhibitors Disrupting β-Catenin’s Interactions with Its Nuclear Partners

(2022) Hao Zhang et al.   Journal of Medicinal Chemistry

Structure-Based Drug Design and Synthesis of Novel N-Aryl-2,4-bithiazole-2-amine CYP1B1-Selective Inhibitors in Overcoming Taxol Resistance in A549 Cells

(2022) Jianping Mao et al.   Journal of Medicinal Chemistry

Imaging of Fibroblast Activation Protein in Cancer Xenografts Using Novel (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine-Based Small Molecules

(2021) Stephanie L. Slania et al.   JOURNAL OF MEDICINAL CHEMISTRY

Visualizing Tumors in Real Time: A Highly Sensitive PSMA Probe for NIR-II Imaging and Intraoperative Tumor Resection

(2021) Longfei Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation

(2020) Li Zhou et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Radiolabeling, and Biological Evaluation of the cis Stereoisomers of 1-Amino-3-Fluoro-4-(fluoro-18F)Cyclopentane-1-Carboxylic Acid as PET Imaging Agents

(2020) Thomas C. Pickel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cancer chemoprevention revisited: Cytochrome P450 family 1B1 as a target in the tumor and the microenvironment

(2018) Gabriele D'Uva et al.   CANCER TREATMENT REVIEWS

Targeting Cytochrome P450 (CYP) 1B1 Enzyme with Four Series of A-ring Substituted Estrane Derivatives: Design, Synthesis, Inhibitory Activity and Selectivity

(2018) Raphaël Dutour et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Novel Estrogen Receptor α-Targeted Near-Infrared Fluorescent Probe for in Vivo Detection of Breast Tumor

(2018) Chu Tang et al.   MOLECULAR PHARMACEUTICS

Design, Synthesis, and Biological Evaluation of Cytochrome P450 1B1 Targeted Molecular Imaging Probes for Colorectal Tumor Detection

(2018) Qingqing Meng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1

(2018) Mohd Usman Mohd Siddique et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibitors of cytochrome P450 (CYP) 1B1

(2017) Raphaël Dutour et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery and characterization of novel CYP1B1 inhibitors based on heterocyclic chalcones: Overcoming cisplatin resistance in CYP1B1-overexpressing lines

(2017) Neill J. Horley et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Quinazoline derivatives as selective CYP1B1 inhibitors

(2017) Mohd Usman Mohd Siddique et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

The role of AHR-inducible cytochrome P450s in metabolism of polyunsaturated fatty acids

(2016) Oliver Hankinson   DRUG METABOLISM REVIEWS

Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment

(2016) Carly C. Barron et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression

(2015) Jiahua Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and evaluation of the inhibitory selectivity of novel trans-resveratrol analogues on human recombinant CYP1A1, CYP1A2 and CYP1B1

(2012) Renata Mikstacka et al.   BIOORGANIC & MEDICINAL CHEMISTRY

CYP1B1 and hormone-induced cancer

(2012) Ketan Gajjar et al.   CANCER LETTERS

Structural Characterization of the Complex between α-Naphthoflavone and Human Cytochrome P450 1B1

(2010) An Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

P450 CYP1B1 mediated fluorescent tumor markers: A potentially useful approach for photodynamic therapy, diagnosis and establishing surgical margins

(2008) William R. Ware   MEDICAL HYPOTHESES