C-Reactive Protein Signaling Pathways in Tumor Progression

NLRP3 Inflammasome as Therapeutic Targets in Inflammatory Diseases

(2023) Annamneedi Venkata Prakash et al.   Biomolecules & Therapeutics

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The Inflammatory Profile of the Tumor Microenvironment, Orchestrated by Cyclooxygenase-2, Promotes Epithelial-Mesenchymal Transition

(2021) Fernán Gómez-Valenzuela et al.   Frontiers in Oncology

Cancer statistics, 2019

(2019) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CRP-Induced NLRP3 Inflammasome Activation Increases LDL Transcytosis Across Endothelial Cells

(2019) Fang Bian et al.   Frontiers in Pharmacology

C-Reactive Protein Promotes Inflammation through FcγR-Induced Glycolytic Reprogramming of Human Macrophages

(2019) Melissa Newling et al.   JOURNAL OF IMMUNOLOGY

Inflammation and Cancer: Triggers, Mechanisms, and Consequences

(2019) Florian R. Greten et al.   IMMUNITY

C-reactive protein (CRP) promotes malignant properties in pancreatic neuroendocrine neoplasms

(2019) Simon Schimmack et al.   Endocrine Connections

Potent repression of C-reactive protein (CRP) expression by the JAK1/2 inhibitor ruxolitinib in inflammatory human hepatocytes

(2019) Marie Febvre-James et al.   INFLAMMATION RESEARCH

FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming

(2018) Ivo S. Hansen et al.   Nature Communications

Macrophages sensing oxidized DAMPs reprogram their metabolism to support redox homeostasis and inflammation through a TLR2-Syk-ceramide dependent mechanism

(2018) Vlad Serbulea et al.   Molecular Metabolism

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Akt Signaling Pathway in Macrophage Activation and M1/M2 Polarization

(2017) Eleni Vergadi et al.   JOURNAL OF IMMUNOLOGY

Cell plasticity in epithelial homeostasis and tumorigenesis

(2017) Julia Varga et al.   NATURE CELL BIOLOGY

C-reactive protein binds to integrin α2 and Fcγ receptor I, leading to breast cell adhesion and breast cancer progression

(2017) E-S Kim et al.   ONCOGENE

mCRP triggers angiogenesis by inducing F3 transcription and TF signalling in microvascular endothelial cells

(2017) Esther Peña et al.   THROMBOSIS AND HAEMOSTASIS

Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States

(2017) Arvind Dasari et al.   JAMA Oncology

The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis

(2017) Ross D. Dolan et al.   Scientific Reports

Overall prognostic impact of C-reactive protein level in patients with metastatic renal cell carcinoma treated with sorafenib

(2016) Tetsuo Fujita et al.   ANTI-CANCER DRUGS

Pre-diagnostic high-sensitive C-reactive protein and breast cancer risk, recurrence, and survival

(2016) H. Frydenberg et al.   BREAST CANCER RESEARCH AND TREATMENT

Association of adiposity, dysmetabolisms, and inflammation with aggressive breast cancer subtypes: a cross-sectional study

(2016) Roberto Agresti et al.   BREAST CANCER RESEARCH AND TREATMENT

Critical evaluation of the potential prognostic value of the pretreatment-derived neutrophil–lymphocyte ratio under consideration of C-reactive protein levels in clear cell renal cell carcinoma

(2016) Orietta Dalpiaz et al.   BRITISH JOURNAL OF CANCER

Cancer statistics, 2016

(2016) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cytology diagnosis of metastatic clear cell renal cell carcinoma, synchronous to pancreas, and metachronous to thyroid and contralateral adrenal: Report of a case and literature review

(2016) Aqiba Bokhari et al.   DIAGNOSTIC CYTOPATHOLOGY

Enhanced pro-protein convertase subtilisin/kexin type 9 expression by C-reactive protein through p38MAPK-HNF1α pathway in HepG2 cells

(2016) Chuan-Jue Cui et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

C-Reactive Protein as a New Prognostic Factor for Survival in Patients With Pancreatic Neuroendocrine Neoplasia

(2016) Dominik Wiese et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Update on the Diagnosis and Management of Renal Angiomyolipoma

(2016) Andrew S. Flum et al.   JOURNAL OF UROLOGY

Strong correlation between early stage atherosclerosis and electromechanical coupling of aorta

(2016) X. Y. Liu et al.   Nanoscale

C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1α via CD64/PI3k/Akt and MAPK/ERK signaling pathways

(2016) JiaYuan Chen et al.   Stem Cell Research & Therapy

Recent insights into the cellular biology of atherosclerosis

(2015) Ira Tabas et al.   JOURNAL OF CELL BIOLOGY

Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer

(2015) Takahiro Kishi et al.   PANCREATOLOGY

Renal cell carcinoma metastases to the pancreas and the thyroid gland 19 years after the primary tumour

(2015) Sylwia Wolf et al.   Przeglad Gastroenterologiczny

Bilateral synchronous adrenal metastases of renal cell carcinoma: A case report and review of the literature

(2015) HAKAN ÖZTÜRK   Oncology Letters

Monomeric C-reactive protein-a key molecule driving development of Alzheimer’s disease associated with brain ischaemia?

(2015) M. Slevin et al.   Scientific Reports

C-Reactive Protein Is an Important Biomarker for Prognosis Tumor Recurrence and Treatment Response in Adult Solid Tumors: A Systematic Review

(2015) Shiva Shrotriya et al.   PLoS One

C-reactive protein and postmenopausal breast cancer risk: results from the E3N cohort study

(2014) Laure Dossus et al.   CANCER CAUSES & CONTROL

C-Reactive Protein Induces Pulmonary Artery Smooth Cell Proliferation Via Modulation of ERK1/2, Akt and NF-κB Pathways

(2014) Jie Li et al.   Clinical Laboratory

Monomeric C-reactive protein and Notch-3 co-operatively increase angiogenesis through PI3K signalling pathway

(2014) Emhamed Boras et al.   CYTOKINE

The proinflammatory effect of C-reactive protein on human endothelial cells depends on the FcγRIIa genotype

(2014) Dorette Raaz-Schrauder et al.   THROMBOSIS RESEARCH

Toll-like receptors and damage-associated molecular patterns: novel links between inflammation and hypertension

(2013) Cameron G. McCarthy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Preoperative Serum C-Reactive Protein Levels and Early Breast Cancer by BMI and Menopausal Status

(2013) Tingting Hong et al.   CANCER INVESTIGATION

Molecular Pathways: The Complex Roles of Inflammation Pathways in the Development and Treatment of Liver Cancer

(2013) K. Nikolaou et al.   CLINICAL CANCER RESEARCH

Biology and trafficking of ATG9 and ATG16L1, two proteins that regulate autophagosome formation

(2013) Eszter Zavodszky et al.   FEBS LETTERS

Inflammatory lipid sphingosine-1-phosphate upregulates C-reactive protein via C/EBPβ and potentiates breast cancer progression

(2013) E-S Kim et al.   ONCOGENE

C-reactive protein and atherothrombosis: Cause or effect?

(2012) Etty Grad et al.   BLOOD REVIEWS

Single determination of C-reactive protein at the time of diagnosis predicts long-term outcome of patients with hepatocellular carcinoma

(2012) Wolfgang Sieghart et al.   HEPATOLOGY

PAMPs and DAMPs: signal 0s that spur autophagy and immunity

(2012) Daolin Tang et al.   IMMUNOLOGICAL REVIEWS

Dissecting the Heterogeneity of Triple-Negative Breast Cancer

(2012) Otto Metzger-Filho et al.   JOURNAL OF CLINICAL ONCOLOGY

The pro-atherogenic effects of macrophages are reduced upon formation of a complex between C-reactive protein and lysophosphatidylcholine

(2012) Mi-Kyung Chang et al.   Journal of Inflammation-London

C-Reactive Protein Induces Interleukin-6 and Thrombospondin-1 Protein and mRNA Expression through Activation of Nuclear Factor-ĸB in HK-2 Cells

(2012) Hai-rong Wang et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Increased Levels of COX-2 and Prostaglandin E 2 Contribute to Elevated Aromatase Expression in Inflamed Breast Tissue of Obese Women

(2012) Kotha Subbaramaiah et al.   Cancer Discovery

Does C-Reactive Protein Contribute to Atherothrombosis Via Oxidant-Mediated Release of Pro-Thrombotic Factors and Activation of Platelets?

(2012) Zhuo Zhang et al.   Frontiers in Physiology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Meta-Analysis of Genome-Wide Association Studies in >80 000 Subjects Identifies Multiple Loci for C-Reactive Protein Levels

(2011) Abbas Dehghan et al.   CIRCULATION

Coupling of Fcγ Receptor I to Fcγ Receptor IIB by Src Kinase Mediates C-Reactive Protein Impairment of Endothelial Function

(2011) Nathan C. Sundgren et al.   CIRCULATION RESEARCH

Clinical significance of preoperative serum interleukin-6 and C-reactive protein level in breast cancer patients

(2011) Praveen Ravishankaran et al.   World Journal of Surgical Oncology

The cachexia score (CASCO): a new tool for staging cachectic cancer patients

(2011) Josep M. Argilés et al.   Journal of Cachexia Sarcopenia and Muscle

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

C-reactive protein is a mediator of cardiovascular disease

(2010) R. J. Bisoendial et al.   EUROPEAN HEART JOURNAL

Prognostic role of systemic inflammatory response in renal cell carcinoma: a systematic review and meta-analysis

(2010) Ying Wu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Modified C-Reactive Protein Is Expressed by Stroke Neovessels and Is a Potent Activator of Angiogenesis In Vitro

(2009) Mark Slevin et al.   BRAIN PATHOLOGY

Serum C-reactive protein concentration and the prognosis of ductal adenocarcinoma of the head of pancreas

(2009) J.K. Pine et al.   EJSO

CRP regulates the expression and activity of tissue factor as well as tissue factor pathway inhibitor via NF-κB and ERK 1/2 MAPK pathway

(2009) YangXin Chen et al.   FEBS LETTERS

Role of systemic inflammatory response in predicting survival in patients with primary operable cancer

(2009) Campbell SD Roxburgh et al.   Future Oncology

Elevated Biomarkers of Inflammation Are Associated With Reduced Survival Among Breast Cancer Patients

(2009) Brandon L. Pierce et al.   JOURNAL OF CLINICAL ONCOLOGY

C-reactive protein (CRP) increases VEGF-A expression in monocytic cells via a PI3-kinase and ERK 1/2 signaling dependent pathway

(2008) Gaëlle Bello et al.   ATHEROSCLEROSIS

C-reactive protein exerts angiogenic effects on vascular endothelial cells and modulates associated signalling pathways and gene expression

(2008) Marta M Turu et al.   BMC CELL BIOLOGY

Preoperative C-reactive protein levels are associated with tumor size and lymphovascular invasion in resected non-small cell lung cancer

(2008) Jin Gu Lee et al.   LUNG CANCER

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE