An acid-responsive MOF nanomedicine for augmented anti-tumor immunotherapy via a metal ion interference-mediated pyroptotic pathway

A Forward Vision for Chemodynamic Therapy: Issues and Opportunities

(2023) Peiran Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

GSDME-mediated pyroptosis promotes the progression and associated inflammation of atherosclerosis

(2023) Yuanyuan Wei et al.   Nature Communications

T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles

(2023) Verena Turco et al.   Nature Communications

Biodegradable MnO-Based Nanoparticles with Engineering Surface for Tumor Therapy: Simultaneous Fenton-Like Ion Delivery and Immune Activation

(2022) Zhaoli Sun et al.   ACS Nano

Mitochondria-Targeting Polymer Micelle of Dichloroacetate Induced Pyroptosis to Enhance Osteosarcoma Immunotherapy

(2022) Jiakang Jin et al.   ACS Nano

The complex role of tumor-infiltrating macrophages

(2022) Anthos Christofides et al.   NATURE IMMUNOLOGY

Biomineralized Two‐Enzyme Nanoparticles Regulated Tumor Glycometabolism Inducing Tumor Cell Pyroptosis and Robust Anti‐Tumor Immunotherapy

(2022) Sijia Zhang et al.   ADVANCED MATERIALS

Etching Bulk Covalent Organic Frameworks into Nanoparticles of Uniform and Controllable Size by the Molecular Exchange Etching Method for Sonodynamic and Immune Combination Antitumor Therapy

(2022) Dianwei Wang et al.   ADVANCED MATERIALS

Immunomodulatory‐Photodynamic Nanostimulators for Invoking Pyroptosis to Augment Tumor Immunotherapy

(2022) Wei Qiu et al.   Advanced Healthcare Materials

A Dual‐Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis

(2022) Wen Su et al.   ADVANCED MATERIALS

Switching from Apoptosis to Pyroptosis: Gasdermin-Elicited Inflammation and Antitumor Immunity

(2021) Kohsuke Tsuchiya   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

(2021) Baicheng Wei et al.   NANO LETTERS

Pyroptosis at the forefront of anticancer immunity

(2021) Reid Loveless et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Manipulating Intratumoral Fenton Chemistry for Enhanced Chemodynamic and Chemodynamic‐Synergized Multimodal Therapy

(2021) Yaofeng Zhou et al.   ADVANCED MATERIALS

T lymphocyte membrane-decorated epigenetic nanoinducer of interferons for cancer immunotherapy

(2021) Yihui Zhai et al.   Nature Nanotechnology

Resolving inflammation by TAM receptor activation

(2021) Juliana P. Vago et al.   PHARMACOLOGY & THERAPEUTICS

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

Macrophages and the maintenance of homeostasis

(2020) David M. Mosser et al.   Cellular & Molecular Immunology

Interleukin-18 in Health and Disease

(2019) Koubun Yasuda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy

(2019) Rong-Hui Deng et al.   ACS Nano

A Designer Scaffold with Immune Nanoconverters for Reverting Immunosuppression and Enhancing Immune Checkpoint Blockade Therapy

(2019) Hathaichanok Phuengkham et al.   ADVANCED MATERIALS

Gasdermins and their role in immunity and inflammation

(2019) Pontus Orning et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small-Sized MOF-Constructed Multifunctional Diagnosis and Therapy Platform for Tumor

(2019) Chao Wang et al.   ACS Biomaterials-Science & Engineering

Factors Influencing the Differentiation of Human Monocytic Myeloid-Derived Suppressor Cells Into Inflammatory Macrophages

(2018) Defne Bayik et al.   Frontiers in Immunology

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reaction

(2018) Zhongmin Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Cancer immunoediting and resistance to T cell-based immunotherapy

(2018) Jake S. O’Donnell et al.   Nature Reviews Clinical Oncology

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

(2017) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Toll-like receptors: Significance, ligands, signaling pathways, and functions in mammals

(2017) Mallenahally Kusha Vidya et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Pyroptosis

(2016) Lieselotte Vande Walle et al.   CURRENT BIOLOGY

Pyroptosis triggers pore-induced intracellular traps (PITs) that capture bacteria and lead to their clearance by efferocytosis

(2016) Ine Jorgensen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Programmed necrosis in inflammation: Toward identification of the effector molecules

(2016) D. Wallach et al.   SCIENCE

Effect of TLR Agonists on the Differentiation and Function of Human Monocytic Myeloid-Derived Suppressor Cells

(2015) Jing Wang et al.   JOURNAL OF IMMUNOLOGY

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Mechanisms of inflammasome activation: recent advances and novel insights

(2015) Sivapriya K. Vanaja et al.   TRENDS IN CELL BIOLOGY

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome

(2015) Bradley D. Gelfand et al.   Cell Reports

PERK-ing up autophagy during MYC-induced tumorigenesis

(2013) Souvik Dey et al.   Autophagy

Nanoparticles: Emerging carriers for drug delivery

(2011) Sagar R. Mudshinge et al.   SAUDI PHARMACEUTICAL JOURNAL

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

The Use of TLR7 and TLR8 Ligands for the Enhancement of Cancer Immunotherapy

(2008) E. L. J. M. Smits et al.   ONCOLOGIST