Mitochondrial subtype MB-G3 contains potential novel biomarkers and therapeutic targets associated with prognosis of medulloblastoma

AHCYL1 Is a Novel Biomarker for Predicting Prognosis and Immunotherapy Response in Colorectal Cancer

(2022) Xubin Li et al.   Journal of Oncology

Failure of human rhombic lip differentiation underlies medulloblastoma formation

(2022) Liam D. Hendrikse et al.   NATURE

Unified rhombic lip origins of group 3 and group 4 medulloblastoma

(2022) Kyle S. Smith et al.   NATURE

CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion

(2021) Gianluca L. Russo et al.   Cell Stem Cell

Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas

(2021) Zaili Luo et al.   Frontiers in Cell and Developmental Biology

AHCYL1 senses SAH to inhibit autophagy through interaction with PIK3C3 in an MTORC1-independent manner

(2021) Wei Huang et al.   Autophagy

PAICS is related to glioma grade and can promote glioma growth and migration

(2021) Baoshun Du et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Tumor cells generate astrocyte-like cells that contribute to SHH-driven medulloblastoma relapse

(2021) Duancheng Guo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation

(2021) Christelle Adolphe et al.   MOLECULAR CANCER RESEARCH

Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination

(2021) Vahan Martirosian et al.   Cell Reports

Tximeta: Reference sequence checksums for provenance identification in RNA-seq

(2020) Michael I. Love et al.   PLoS Computational Biology

Pathology, diagnostics, and classification of medulloblastoma

(2020) Brent A. Orr   BRAIN PATHOLOGY

COX6B2 drives metabolic reprogramming toward oxidative phosphorylation to promote metastasis in pancreatic ductal cancer cells

(2020) Ke Nie et al.   Oncogenesis

More Than a Metabolic Enzyme: MTHFD2 as a Novel Target for Anticancer Therapy?

(2020) Zhiyuan Zhu et al.   Frontiers in Oncology

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Metascape provides a biologist-oriented resource for the analysis of systems-level datasets

(2019) Yingyao Zhou et al.   Nature Communications

Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy

(2019) Chantal Hoi Yin Cheung et al.   Cell Death & Disease

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

(2018) Sebastian M Waszak et al.   LANCET ONCOLOGY

A Role for De Novo Purine Metabolic Enzyme PAICS in Bladder Cancer Progression

(2018) Balabhadrapatruni V.S.K. Chakravarthi et al.   NEOPLASIA

The whole-genome landscape of medulloblastoma subtypes

(2017) Paul A. Northcott et al.   NATURE

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

(2017) Tristan Gallenne et al.   Oncotarget

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Childhood medulloblastoma

(2016) Maura Massimino et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer

(2016) Balabhadrapatruni V. S. K. Chakravarthi et al.   PROSTATE

The GABA Transaminase, ABAT, Is Essential for Mitochondrial Nucleoside Metabolism

(2015) Arnaud Besse et al.   Cell Metabolism

Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer

(2015) Moloy T. Goswami et al.   Oncotarget

MRI Surrogates for Molecular Subgroups of Medulloblastoma

(2014) S. Perreault et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Gene Expression Analyses of the Spatio-Temporal Relationships of Human Medulloblastoma Subgroups during Early Human Neurogenesis

(2014) Cornelia M. Hooper et al.   PLoS One

Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer

(2014) Roland Nilsson et al.   Nature Communications

Paradoxical expression of AHCYL1 affecting ovarian carcinogenesis between chickens and women

(2012) Wooyoung Jeong et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The incidence of medulloblastomas and primitive neurectodermal tumours in adults and children

(2012) Nicolas R. Smoll et al.   JOURNAL OF CLINICAL NEUROSCIENCE

The potential impact of tumour biology on improved clinical practice for medulloblastoma: progress towards biologically driven clinical trials

(2009) Barry L. Pizer et al.   BRITISH JOURNAL OF NEUROSURGERY