Synthesis of 3-chloro-6-((4-(di-tert-butyl[18F]fluorosilyl)-benzyl)oxy)-1,2,4,5-tetrazine ([18F]SiFA-OTz) for rapid tetrazine-based 18F-radiolabeling

An Organotrifluoroborate for Broadly Applicable One-Step18F-Labeling

(2014) Zhibo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Development of a18F-Labeled Tetrazine with Favorable Pharmacokinetics for Bioorthogonal PET Imaging

(2014) Christoph Denk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rapid 18F-Labeling and Loading of PEGylated Gold Nanoparticles for in Vivo Applications

(2014) Jun Zhu et al.   BIOCONJUGATE CHEMISTRY

Facile Covalent Modification of a Highly Ordered Pyrolytic Graphite Surface via an Inverse Electron Demand Diels–Alder Reaction under Ambient Conditions

(2014) Jun Zhu et al.   CHEMISTRY OF MATERIALS

Theoretical Elucidation of the Origins of Substituent and Strain Effects on the Rates of Diels–Alder Reactions of 1,2,4,5-Tetrazines

(2014) Fang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemical modification of single walled carbon nanotubes with tetrazine-tethered gold nanoparticles via a Diels–Alder reaction

(2013) Jun Zhu et al.   CHEMICAL COMMUNICATIONS

Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation

(2013) Matthias M. Herth et al.   CHEMICAL COMMUNICATIONS

trans-Cyclooctene—a stable, voracious dienophile for bioorthogonal labeling

(2013) Ramajeyam Selvaraj et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Development and Evaluation of 18F-TTCO-Cys40-Exendin-4: A PET Probe for Imaging Transplanted Islets

(2013) Z. Wu et al.   JOURNAL OF NUCLEAR MEDICINE

Bioorthogonal chemistry for pre-targeted molecular imaging – progress and prospects

(2013) Laurence Carroll et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions

(2013) James C. Knight et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Genetically Encoded Tetrazine Amino Acid Directs Rapid Site-Specific in Vivo Bioorthogonal Ligation with trans-Cyclooctenes

(2012) Jason L. Seitchik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology

(2012) Carmen Wängler et al.   Nature Protocols

Reactive polymer enables efficient in vivo bioorthogonal chemistry

(2012) N. K. Devaraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Silicon-[18F]Fluorine Radiochemistry: Basics, Applications and Challenges

(2012) Carmen Wängler et al.   Applied Sciences-Basel

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Biomedical Applications of Tetrazine Cycloadditions

(2011) Neal K. Devaraj et al.   ACCOUNTS OF CHEMICAL RESEARCH

Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification

(2011) Ghyslain Budin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and In Vivo Imaging of a 18F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method

(2011) Thomas Reiner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging

(2011) Mark R. Karver et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Yielding Aqueous18F-Labeling of Peptides via Al18F Chelation

(2011) Christopher A. D’Souza et al.   BIOCONJUGATE CHEMISTRY

Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin αvβ3 targeted PET tracer based on a cyclic RGD peptide

(2011) Ramajeyam Selvaraj et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

High-Yielding, Two-Step18F Labeling Strategy for18F-PARP1 Inhibitors

(2011) Edmund J. Keliher et al.   ChemMedChem

Diels–Alder Cycloaddition for Fluorophore Targeting to Specific Proteins inside Living Cells

(2011) Daniel S. Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

One-Step18F-Labeling of Carbohydrate-Conjugated Octreotate-Derivatives Containing a Silicon-Fluoride-Acceptor (SiFA): In Vitro and in Vivo Evaluation as Tumor Imaging Agents for Positron Emission Tomography (PET)

(2010) Carmen Wängler et al.   BIOCONJUGATE CHEMISTRY

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

(2010) Zibo Li et al.   CHEMICAL COMMUNICATIONS

para-Functionalized Aryl-di-tert-butylfluorosilanes as Potential Labeling Synthons for18F Radiopharmaceuticals

(2009) Ljuba Iovkova et al.   CHEMISTRY-A EUROPEAN JOURNAL

Silicon-Based Building Blocks for One-Step18F-Radiolabeling of Peptides for PET Imaging

(2008) Linjing Mu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of11C,18F,15O, and13N Radiolabels for Positron Emission Tomography

(2008) Philip W. Miller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY