Bioorthogonal chemistry for pre-targeted molecular imaging – progress and prospects

Development of a 11C-labeled tetrazine for rapid tetrazine–trans-cyclooctene ligation

(2013) Matthias M. Herth et al.   CHEMICAL COMMUNICATIONS

Live-Cell Imaging of Cyclopropene Tags with Fluorogenic Tetrazine Cycloadditions

(2012) Jun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metal-Catalyzed One-Pot Synthesis of Tetrazines Directly from Aliphatic Nitriles and Hydrazine

(2012) Jun Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

(2012) Kathrin Lang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of an integrin αvβ6-specific peptide labeled with [18F]fluorine by copper-free, strain-promoted click chemistry

(2012) Sven H. Hausner et al.   NUCLEAR MEDICINE AND BIOLOGY

Copper catalysed azide–alkyne cycloaddition (CuAAC) in liquid ammonia

(2012) Pengju Ji et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

Strain-Promoted Copper-Free “Click” Chemistry for 18F Radiolabeling of Bombesin

(2011) Lachlan S. Campbell-Verduyn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

(2011) Christen Besanceney-Webler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

[18F]Azadibenzocyclooctyne ([18F]ADIBO): A biocompatible radioactive labeling synthon for peptides using catalyst free [3+2] cycloaddition

(2011) Selvanathan Arumugam et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Copper-free click—a promising tool for pre-targeted PET imaging

(2011) Helen L. Evans et al.   CHEMICAL COMMUNICATIONS

A Bioorthogonal Quadricyclane Ligation

(2011) Ellen M. Sletten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploring isonitrile-based click chemistry for ligation with biomolecules

(2011) Henning Stöckmann et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper-free click chemistry with the short-lived positron emitter fluorine-18

(2011) Vincent Bouvet et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Protein Modification by Strain-Promoted Alkyne-Nitrone Cycloaddition

(2010) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

(2010) Zibo Li et al.   CHEMICAL COMMUNICATIONS

The traceless Staudinger ligation for indirect18F-radiolabelling

(2010) Laurence Carroll et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Copper-free click chemistry in living animals

(2010) P. V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ring Strain Energy in the Cyclooctyl System. The Effect of Strain Energy on [3 + 2] Cycloaddition Reactions with Azides

(2009) Robert D. Bach   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Free “Click” Modification of DNA via Nitrile Oxide−Norbornene 1,3-Dipolar Cycloaddition

(2009) Katrin Gutsmiedl et al.   ORGANIC LETTERS

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish

(2008) S. T. Laughlin et al.   SCIENCE