Plumbagin has an inhibitory effect on the growth of TSCC PDX model and it enhances the anticancer efficacy of cisplatin

From resistance to resilience: Uncovering chemotherapeutic resistance mechanisms; insights from established models

(2023) Nourhan M. Abdelmaksoud et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

RNA polymerase II subunit 3 regulates vesicular, overexpressed in cancer, prosurvival protein 1 expression to promote hepatocellular carcinoma

(2021) Peng Hu et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression

(2021) Swati Goel et al.   Frontiers in Pharmacology

Prognostic biomarkers and therapeutic targets in oral squamous cell carcinoma: a study based on cross-database analysis

(2021) Wanli Yang et al.   HEREDITAS

DCBLD2 Affects the Development of Colorectal Cancer via EMT and Angiogenesis and Modulates 5-FU Drug Resistance

(2021) Pan Xie et al.   Frontiers in Cell and Developmental Biology

Activation of Aquaporin 5 by carcinogenic Helicobacter pylori infection promotes epithelial‐mesenchymal transition via the MEK/ERK pathway

(2021) Nianshuang Li et al.   HELICOBACTER

Plumbagin suppresses non-small cell lung cancer progression through downregulating ARF1 and by elevating CD8+ T cells

(2021) Ze-Bo Jiang et al.   PHARMACOLOGICAL RESEARCH

Current research developments of patient‑derived tumour xenograft models (Review)

(2021) Zhenyu Yin et al.   Experimental and Therapeutic Medicine

Anti‑Axl monoclonal antibodies attenuate the migration of MDA‑MB‑231 breast cancer cells

(2021) Hong Chang et al.   Oncology Letters

Long non‑coding RNA OIP5‑AS1 promotes the progression of esophageal cancer by regulating miR‑30a/VOPP1 expression

(2021) Jiajun Xu et al.   Oncology Letters

Role of NRP1 in Bladder Cancer Pathogenesis and Progression

(2021) Yang Dong et al.   Frontiers in Oncology

Different effects of anti-VEGF drugs (Ranibizumab, Aflibercept, Conbercept) on autophagy and its effect on neovascularization in RF/6A cells

(2021) Yi Wang et al.   MICROVASCULAR RESEARCH

Identification of a potential target for treatment of squamous cell carcinoma of the tongue: follistatin

(2020) M. Yu et al.   BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY

Biomarkers for immunotherapy response in head and neck cancer

(2020) Niki Gavrielatou et al.   CANCER TREATMENT REVIEWS

Long non‑coding RNA LINC00152 acts as a sponge of miRNA‑193b‑3p to promote tongue squamous cell carcinoma progression

(2020) Xiuhua Li et al.   Oncology Letters

AXL as a Target in Breast Cancer Therapy

(2020) Sierra A. Colavito   Journal of Oncology

Cisplatin and farnesol co-encapsulated PLGA nano-particles demonstrate enhanced anti-cancer potential against hepatocellular carcinoma cells in vitro

(2020) Jesmin Mondal et al.   MOLECULAR BIOLOGY REPORTS

Plumbagin Enhances the Anticancer Efficacy of Cisplatin by Increasing Intracellular ROS in Human Tongue Squamous Cell Carcinoma

(2020) Danfeng Xue et al.   Oxidative Medicine and Cellular Longevity

Chemotherapy-induced peripheral neuropathy—part 2: focus on the prevention of oxaliplatin-induced neurotoxicity

(2020) Kinga Sałat   Pharmacological Reports

YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

(2020) Hirofumi Omori et al.   Science Advances

Nomogram Based on Systemic Immune-Inflammation Index to Predict Survival of Tongue Cancer Patients Who Underwent Cervical Dissection

(2020) Zhiyuan Lu et al.   Frontiers in Oncology

Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma

(2020) Emil Aagaard Thomsen et al.   Molecular Oncology

The selective c-Met inhibitor capmatinib offsets cisplatin-nephrotoxicity and doxorubicin-cardiotoxicity and improves their anticancer efficacies

(2020) Mohamed E. Shaker et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR

(2020) Ji Geng et al.   Cell Death & Disease

Effects of Selected Nigerian Medicinal Plants on the Viability, Mobility, and Multidrug-Resistant Mechanisms in Liver, Colon, and Skin Cancer Cell Lines

(2020) Aljawharah AlQathama et al.   Frontiers in Pharmacology

Establishment of a Jaw Fibrosarcoma Patient-Derived Xenograft and Evaluation of the Tumor Suppression Efficacy of Plumbagin Against Jaw Fibrosarcoma

(2020) Yuqi Xin et al.   Frontiers in Oncology

Autophagy-mediated cytoplasmic accumulation of p53 leads to apoptosis through DRAM-BAX in cadmium-exposed human proximal tubular cells

(2020) Hyun-Young Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anticancer Effects and Mechanisms of Action of Plumbagin: Review of Research Advances

(2020) Zhenhua Yin et al.   Biomed Research International

Plumbagin Ameliorates Collagen-Induced Arthritis by Regulating Treg/Th17 Cell Imbalances and Suppressing Osteoclastogenesis

(2019) Tingyu Wang et al.   Frontiers in Immunology

Time to recurrence and patient survival in recurrent oral squamous cell carcinoma

(2019) Annelies Weckx et al.   ORAL ONCOLOGY

The growth inhibitory effect of human gingiva-derived mesenchymal stromal cells expressing interferon-β on tongue squamous cell carcinoma cells and xenograft model

(2019) Lingqian Du et al.   Stem Cell Research & Therapy

Characterization and radiosensitivity of HPV-related oropharyngeal squamous cell carcinoma patient-derived xenografts

(2019) Jacob Kinggaard Lilja-Fischer et al.   ACTA ONCOLOGICA

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Linking transcriptional and genetic tumor heterogeneity through allele analysis of single-cell RNA-seq data

(2018) Jean Fan et al.   GENOME RESEARCH

Europium(III)-doped yttrium vanadate nanoparticles reduce the toxicity of cisplatin

(2018) Natália Helen Ferreira et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Clinical analysis of second primary gingival squamous cell carcinoma after radiotherapy

(2018) Xiaoyan Fu et al.   ORAL ONCOLOGY

Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling

(2018) Ying-Ya Cao et al.   Cell Death & Disease

CD47 as a potential prognostic marker for oral leukoplakia and oral squamous cell carcinoma

(2018) Xiaojing Ye et al.   Oncology Letters

A correlation research of Ki67 index, CT features, and risk stratification in gastrointestinal stromal tumor

(2018) Huali Li et al.   Cancer Medicine

Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection

(2018) Wei Gu et al.   Annual Review of Pathology-Mechanisms of Disease

Phytochemicals: Current strategy to sensitize cancer cells to cisplatin

(2018) Chao-Yue Sun et al.   BIOMEDICINE & PHARMACOTHERAPY

Next-Generation Sequencing Analysis and Algorithms for PDX and CDX Models

(2017) Garima Khandelwal et al.   MOLECULAR CANCER RESEARCH

Aquaporin-5: from structure to function and dysfunction in cancer

(2016) Inês Direito et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of aquaporin-5 in cancer cell migration: A potential active participant

(2016) Helene H. Jensen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phytomedicine—Modulating oxidative stress and the tumor microenvironment for cancer therapy

(2016) Yu-Ting Cheng et al.   PHARMACOLOGICAL RESEARCH

Spatial Heterogeneity in the Tumor Microenvironment

(2016) Yinyin Yuan   Cold Spring Harbor Perspectives in Medicine

Immunology and Immunotherapy of Head and Neck Cancer

(2015) Robert L. Ferris   JOURNAL OF CLINICAL ONCOLOGY

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective

(2015) Samuel H. Myers et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive genomic characterization of head and neck squamous cell carcinomas

(2015)   NATURE

Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

Mitochondrial fission determines cisplatin sensitivity in tongue squamous cell carcinoma through the BRCA1–miR-593-5p–MFF axis

(2015) Song Fan et al.   Oncotarget

Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research

(2014) M. Hidalgo et al.   Cancer Discovery

Plumbagin inhibits prostate cancer development in TRAMP mice via targeting PKC , Stat3 and neuroendocrine markers

(2012) B. B. Hafeez et al.   CARCINOGENESIS

Randomized Phase III Trial of Induction Chemotherapy With Docetaxel, Cisplatin, and Fluorouracil Followed by Surgery Versus Up-Front Surgery in Locally Advanced Resectable Oral Squamous Cell Carcinoma

(2012) Lai-ping Zhong et al.   JOURNAL OF CLINICAL ONCOLOGY

A Molecularly Annotated Platform of Patient-Derived Xenografts ("Xenopatients") Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer

(2011) A. Bertotti et al.   Cancer Discovery

Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects

(2011) Ana-Maria Florea et al.   Cancers

Oral tongue squamous cell carcinoma: recurrent disease is associated with histopathologic risk score and young age

(2010) Marilena Vered et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Living with oral cancer: Epidemiology with particular reference to prevalence and life-style changes that influence survival

(2010) Saman Warnakulasuriya   ORAL ONCOLOGY

Outcome of oral tongue squamous cell carcinoma in patients with and without known risk factors

(2010) G. Bachar et al.   ORAL ONCOLOGY