Single Particle Chemical Characterisation of Nanoformulations for Cargo Delivery

Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy

(2023) Ana Camila Marques et al.   Pharmaceutics

Revealing Population Heterogeneity in Vesicle-Based Nanomedicines Using Automated, Single Particle Raman Analysis

(2023) Catherine Saunders et al.   ACS Nano

Valency and affinity control of aptamer-conjugated nanoparticles for selective cancer cell targeting

(2023) Laura Woythe et al.   JOURNAL OF CONTROLLED RELEASE

Fluorescence Correlation Spectroscopy Monitors the Fate of Degradable Nanocarriers in the Blood Stream

(2022) Sascha Schmitt et al.   BIOMACROMOLECULES

Shining Light on Polymeric Drug Nanocarriers with Fluorescence Correlation Spectroscopy

(2022) Sascha Schmitt et al.   MACROMOLECULAR RAPID COMMUNICATIONS

A Review of Liposomes as a Drug Delivery System: Current Status of Approved Products, Regulatory Environments, and Future Perspectives

(2022) Peng Liu et al.   MOLECULES

Quantification of Available Ligand Density on the Surface of Targeted Liposomal Nanomedicines at the Single-Particle Level

(2022) Chaoxiang Chen et al.   ACS Nano

Coupling Lipid Nanoparticle Structure and Automated Single‐Particle Composition Analysis to Design Phospholipase‐Responsive Nanocarriers

(2022) Hanna M. G. Barriga et al.   ADVANCED MATERIALS

Strategies for improving the safety and RNAi efficacy of noncovalent peptide/siRNA nanocomplexes

(2022) Jun Wang et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

Potent Virustatic Polymer–Lipid Nanomimics Block Viral Entry and Inhibit Malaria Parasites In Vivo

(2022) Adrian Najer et al.   ACS Central Science

Multicolor Super-Resolution Microscopy of Protein Corona on Single Nanoparticles

(2022) Yuyang Wang et al.   ACS Applied Materials & Interfaces

Block Length‐Dependent Protein Fouling on Poly(2‐oxazoline)‐Based Polymersomes: Influence on Macrophage Association and Circulation Behavior

(2022) Adrian Najer et al.   Small

Polymer functionalization of inorganic nanoparticles for biomedical applications

(2022) Tobias Komsthöft et al.   Current Opinion in Chemical Engineering

Functionalized Peptide-Based Nanoparticles for Targeted Cancer Nanotherapeutics: A State-of-the-Art Review

(2022) Ritika Sharma et al.   ACS Omega

Differences in Human Plasma Protein Interactions between Various Polymersomes and Stealth Liposomes as Observed by Fluorescence Correlation Spectroscopy

(2022) Adrian Najer et al.   MACROMOLECULAR BIOSCIENCE

Characterization of lipid-based nanomedicines at the single-particle level

(2022) Chaoxiang Chen et al.   Fundamental Research

A Versatile Platform for Generating Engineered Extracellular Vesicles with Defined Therapeutic Properties

(2021) Kevin Dooley et al.   MOLECULAR THERAPY

Encapsulation state of messenger RNA inside lipid nanoparticles

(2021) Mark L. Brader et al.   BIOPHYSICAL JOURNAL

mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

(2021) Linde Schoenmaker et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Seeing beyond the limit: a guide to choosing the right super resolution microscopy technique

(2021) Jessica Valli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Comprehensive Review of Fluorescence Correlation Spectroscopy

(2021) Lan Yu et al.   Frontiers in Physics

Bioinert, Stealth or Interactive: How Surface Chemistry of Nanocarriers Determines Their Fate In Vivo

(2021) Julian David Friedl et al.   ADVANCED FUNCTIONAL MATERIALS

Correlating Super-Resolution Microscopy and Transmission Electron Microscopy Reveals Multiparametric Heterogeneity in Nanoparticles

(2021) Teodora Andrian et al.   NANO LETTERS

Lipid nanoparticles for mRNA delivery

(2021) Xucheng Hou et al.   Nature Reviews Materials

Transferrin-Conjugated Erianin-Loaded Liposomes Suppress the Growth of Liver Cancer by Modulating Oxidative Stress

(2021) Anhui Yang et al.   Frontiers in Oncology

Ionization and structural properties of mRNA lipid nanoparticles influence expression in intramuscular and intravascular administration

(2021) Manuel J. Carrasco et al.   Communications Biology

Single Particle Automated Raman Trapping Analysis of Breast Cancer Cell-Derived Extracellular Vesicles as Cancer Biomarkers

(2021) Jelle Penders et al.   ACS Nano

Opportunities and Pitfalls of Fluorescent Labeling Methodologies for Extracellular Vesicle Profiling on High-Resolution Single-Particle Platforms

(2021) Diogo Fortunato et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ancillary effects of nanoparticles and their implications for nanomedicine

(2021) Evan P. Stater et al.   Nature Nanotechnology

Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction

(2020) Janel L. Davis et al.   LANGMUIR

Single-particle spectroscopy for functional nanomaterials

(2020) Jiajia Zhou et al.   NATURE

Nanopharmaceutics: Part I—Clinical Trials Legislation and Good Manufacturing Practices (GMP) of Nanotherapeutics in the EU

(2020) Eliana B. Souto et al.   Pharmaceutics

Combined Morpho-Chemical Profiling of Individual Extracellular Vesicles and Functional Nanoparticles without Labels

(2020) Yichuan Dai et al.   ANALYTICAL CHEMISTRY

Targeting nanoparticles to the brain by exploiting the blood–brain barrier impermeability to selectively label the brain endothelium

(2020) Daniel Gonzalez-Carter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thermosensitive Exosome–Liposome Hybrid Nanoparticle‐Mediated Chemoimmunotherapy for Improved Treatment of Metastatic Peritoneal Cancer

(2020) Qijun Lv et al.   Advanced Science

Optimizing imaging speed and excitation intensity for single-molecule localization microscopy

(2020) Robin Diekmann et al.   NATURE METHODS

Controlled Dendrimersome Nanoreactor System for Localized Hypochlorite-Induced Killing of Bacteria

(2020) Michael Potter et al.   ACS Nano

Engineering precision nanoparticles for drug delivery

(2020) Michael J. Mitchell et al.   NATURE REVIEWS DRUG DISCOVERY

Flow Cytometric Analysis of Nanoscale Biological Particles and Organelles

(2019) Hong Lian et al.   Annual Review of Analytical Chemistry

Single-particle characterization of theranostic liposomes with stimulus sensing and controlled drug release properties

(2019) Chaoxiang Chen et al.   BIOSENSORS & BIOELECTRONICS

Folic acid functionalized nanoparticles as pharmaceutical carriers in drug delivery systems

(2019) Asghar Narmani et al.   DRUG DEVELOPMENT RESEARCH

Nanoparticle Characterization: What to Measure?

(2019) Mario M. Modena et al.   ADVANCED MATERIALS

Super-resolution Microscopy for Nanomedicine Research

(2019) Silvia Pujals et al.   ACS Nano

The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs

(2019) Akin Akinc et al.   Nature Nanotechnology

Protein Profiling and Sizing of Extracellular Vesicles from Colorectal Cancer Patients via Flow Cytometry

(2018) Ye Tian et al.   ACS Nano

Modulating Phagocytic Cell Sequestration by Tailoring Nanoconstruct Softness

(2018) Roberto Palomba et al.   ACS Nano

Regulatory challenges of nanomedicines and their follow-on versions: A generic or similar approach?

(2018) Stefan Mühlebach   ADVANCED DRUG DELIVERY REVIEWS

Characterization techniques for nanoparticles: comparison and complementarity upon studying nanoparticle properties

(2018) Stefanos Mourdikoudis et al.   Nanoscale

Super-multiplexed fluorescence microscopy via photostability contrast

(2018) Antony Orth et al.   Biomedical Optics Express

How Entanglement of Different Physicochemical Properties Complicates the Prediction of in Vitro and in Vivo Interactions of Gold Nanoparticles

(2018) Ming Xu et al.   ACS Nano

The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery

(2018) Matthias Bros et al.   Frontiers in Immunology

Nanomedicine: Principles, Properties, and Regulatory Issues

(2018) Sara Soares et al.   Frontiers in Chemistry

Super-resolution Imaging of Proton Sponge-Triggered Rupture of Endosomes and Cytosolic Release of Small Interfering RNA

(2018) Marcin Wojnilowicz et al.   ACS Nano

Temporal Filtering to Improve Single Molecule Identification in High Background Samples

(2018) Alexander Reismann et al.   MOLECULES

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

(2018) Inka Negwer et al.   Nature Communications

Single Particle Automated Raman Trapping Analysis

(2018) Jelle Penders et al.   Nature Communications

PLGA-Based Nanoparticles in Cancer Treatment

(2018) Sima Rezvantalab et al.   Frontiers in Pharmacology

Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona

(2017) Natalia Feiner-Gracia et al.   Small

Affibody Molecules in Biotechnological and Medical Applications

(2017) Stefan Ståhl et al.   TRENDS IN BIOTECHNOLOGY

Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies

(2017) Jiayin Shen et al.   Oncotarget

Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step

(2017) Olga Schäfer et al.   ACS Macro Letters

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

(2017) Aizea Morales-Kastresana et al.   Scientific Reports

Nanomaterial Drug Products: Manufacturing and Analytical Perspectives

(2016) Christie M. Sayes et al.   AAPS Journal

Characterisation of the protein corona using tunable resistive pulse sensing: determining the change and distribution of a particle’s surface charge

(2016) Emma L. C. J. Blundell et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Label-Free Analysis of Single Viruses with a Resolution Comparable to That of Electron Microscopy and the Throughput of Flow Cytometry

(2016) Ling Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Liposomal Amphotericin B (AmBisome®): A Review of the Pharmacokinetics, Pharmacodynamics, Clinical Experience and Future Directions

(2016) Neil R. H. Stone et al.   DRUGS

Transmission electron microscopy for nanomedicine: novel applications for long-established techniques

(2016) Manuela Malatesta   EUROPEAN JOURNAL OF HISTOCHEMISTRY

DLS and zeta potential – What they are and what they are not?

(2016) Sourav Bhattacharjee   JOURNAL OF CONTROLLED RELEASE

Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems

(2016) Silvia Arpicco et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

3D Structures of Responsive Nanocompartmentalized Microgels

(2016) Arjan P. H. Gelissen et al.   NANO LETTERS

Binding of human serum albumin to PEGylated liposomes: insights into binding numbers and dynamics by fluorescence correlation spectroscopy

(2016) Kasper Kristensen et al.   Nanoscale

Nanoformulation and encapsulation approaches for poorly water-soluble drug nanoparticles

(2016) Ulrike Wais et al.   Nanoscale

Elasticity of Nanoparticles Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting

(2015) Aaron C. Anselmo et al.   ACS Nano

In Situ Visualization of Block Copolymer Self-Assembly in Organic Media by Super-Resolution Fluorescence Microscopy

(2015) Charlotte E. Boott et al.   CHEMISTRY-A EUROPEAN JOURNAL

Optical Nanoimaging for Block Copolymer Self-Assembly

(2015) Jie Yan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Release Kinetics Study of Poorly Water-Soluble Drugs from Nanoparticles: Are We Doing It Right?

(2015) Sara A. Abouelmagd et al.   MOLECULAR PHARMACEUTICS

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Millisecond-Timescale Monitoring of PbS Nanoparticle Nucleation and Growth Using Droplet-Based Microfluidics

(2015) Ioannis Lignos et al.   Small

Lipid composition: a “key factor” for the rational manipulation of the liposome–protein corona by liposome design

(2015) G. Caracciolo et al.   RSC Advances

High Resolution Particle Characterization to Expedite Development and Regulatory Acceptance of Nanomedicines

(2015) Darby Kozak et al.   Current Drug Delivery

Confocal Raman Microscopy for Investigating Synthesis and Characterization of Individual Optically Trapped Vinyl-Polymerized Surfactant Particles

(2015) Jonathan J. Schaefer et al.   APPLIED SPECTROSCOPY

High Resolution Characterization of Engineered Nanomaterial Dispersions in Complex Media Using Tunable Resistive Pulse Sensing Technology

(2014) Anoop K. Pal et al.   ACS Nano

Light-Scattering Detection below the Level of Single Fluorescent Molecules for High-Resolution Characterization of Functional Nanoparticles

(2014) Shaobin Zhu et al.   ACS Nano

Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes

(2014) Signe Mathiasen et al.   NATURE METHODS

Heterogeneity in nanoparticles influences biodistribution and targeting

(2013) Isaac M Adjei et al.   Nanomedicine

Simultaneous Size and ζ-Potential Measurements of Individual Nanoparticles in Dispersion Using Size-Tunable Pore Sensors

(2012) Darby Kozak et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Assessing the Heterogeneity Level in Lipid Nanoparticles for siRNA Delivery: Size-Based Separation, Compositional Heterogeneity, and Impact on Bioperformance

(2012) Jingtao Zhang et al.   MOLECULAR PHARMACEUTICS

Aspect Ratio Determines the Quantity of Mesoporous Silica Nanoparticle Uptake by a Small GTPase-Dependent Macropinocytosis Mechanism

(2011) Huan Meng et al.   ACS Nano

Fluorescence Correlation Spectroscopy: Past, Present, Future

(2011) Elliot L. Elson   BIOPHYSICAL JOURNAL

A high-throughput label-free nanoparticle analyser

(2011) Jean-Luc Fraikin et al.   Nature Nanotechnology

Endocytosis of nanomedicines

(2010) Gaurav Sahay et al.   JOURNAL OF CONTROLLED RELEASE

Confocal Raman microscopy for simultaneous monitoring of partitioning and disordering of tricyclic antidepressants in phospholipid vesicle membranes

(2009) Christopher B. Fox et al.   JOURNAL OF RAMAN SPECTROSCOPY

Fluorescence Correlation Spectroscopy: Criteria for Analysis in Complex Systems

(2008) Alexei Tcherniak et al.   ANALYTICAL CHEMISTRY

Surface Charge of Nanoparticles Determines Their Endocytic and Transcytotic Pathway in Polarized MDCK Cells

(2008) Oshrat Harush-Frenkel et al.   BIOMACROMOLECULES

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

(2008) F. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA