The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery

Autoimmune phenomena and disease in cancer patients treated with immune checkpoint inhibitors

(2018) Milena Tocut et al.   AUTOIMMUNITY REVIEWS

The Transferability from Animal Models to Humans: Challenges Regarding Aggregation and Protein Corona Formation of Nanoparticles

(2018) Laura K. Müller et al.   BIOMACROMOLECULES

Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist

(2018) Lutz Nuhn et al.   BIOMATERIALS

Cell membrane-coated nanocarriers: the emerging targeted delivery system for cancer theranostics

(2018) Rajendran JC Bose et al.   DRUG DISCOVERY TODAY

Nanoparticles for dendritic cell-based immunotherapy

(2018) Tuan Hiep Tran et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Protein corona–mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses

(2018) Limei Shen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy

(2018) Bijun Zeng et al.   JOURNAL OF CLINICAL INVESTIGATION

Nanotechnological Strategies for Protein Delivery

(2018) María Rocío Villegas et al.   MOLECULES

In vivo formation of protein corona on gold nanoparticles. The effect of their size and shape

(2018) Rafaela García-Álvarez et al.   Nanoscale

Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies

(2018) Sandra Iurescia et al.   Frontiers in Immunology

Complement C3-dependent uptake of targeted liposomes into human macrophages, B cells, dendritic cells, neutrophils, and MDSCs

(2017) Alexandra Francian et al.   International Journal of Nanomedicine

Oligonucleotide-conjugated nanoparticles for targeted drug delivery via scavenger receptors class A: An in vitro assessment for proof-of-concept

(2017) Ho Yin Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Surface Modification of Polysaccharide-Based Nanoparticles with PEG and Dextran and the Effects on Immune Cell Binding and Stimulatory Characteristics

(2017) Denise Bamberger et al.   MOLECULAR PHARMACEUTICS

Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers

(2017) Yoanna Tsvetkova et al.   NANO LETTERS

Visualization of the protein corona: towards a biomolecular understanding of nanoparticle-cell-interactions

(2017) Maria Kokkinopoulou et al.   Nanoscale

Bacterial endotoxin (lipopolysaccharide) binds to the surface of gold nanoparticles, interferes with biocorona formation and induces human monocyte inflammatory activation

(2017) Yang Li et al.   Nanotoxicology

Non-identical twins: Different faces of CR3 and CR4 in myeloid and lymphoid cells of mice and men

(2017) Anna Erdei et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Nanoparticle decoration with surfactants: Molecular interactions, assembly, and applications

(2017) Hendrik Heinz et al.   SURFACE SCIENCE REPORTS

Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona

(2017) Giulio Caracciolo et al.   TRENDS IN BIOTECHNOLOGY

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Clusterin in the protein corona plays a key role in the stealth effect of nanoparticles against phagocytes

(2016) Michihiko Aoyama et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Poly(ethylene glycol) Crowding as Critical Factor To Determine pDNA Packaging Scheme into Polyplex Micelles for Enhanced Gene Expression

(2016) Kaori M. Takeda et al.   BIOMACROMOLECULES

The importance of selecting a proper biological milieu for protein corona analysis in vitro: Human plasma versus human serum

(2016) Vahid Mirshafiee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Elucidation of structural and functional properties of albumin bound to gold nanoparticles

(2016) Jessy Mariam et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Beyond antigens and adjuvants: formulating future vaccines

(2016) Tyson J. Moyer et al.   JOURNAL OF CLINICAL INVESTIGATION

Vaccination with trifunctional nanoparticles that address CD8+dendritic cells inhibits growth of established melanoma

(2016) Limei Shen et al.   Nanomedicine

Endotoxin contamination: a key element in the interpretation of nanosafety studies

(2016) Yang Li et al.   Nanomedicine

Protein source and choice of anticoagulant decisively affect nanoparticle protein corona and cellular uptake

(2016) S. Schöttler et al.   Nanoscale

Time-evolution of in vivo protein corona onto blood-circulating PEGylated liposomal doxorubicin (DOXIL) nanoparticles

(2016) Marilena Hadjidemetriou et al.   Nanoscale

Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo

(2016) Fangfang Chen et al.   Nature Nanotechnology

Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers

(2016) Susanne Schöttler et al.   Nature Nanotechnology

pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation

(2016) Lutz Nuhn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display

(2016) Philipp Kuhn et al.   Proteomics Clinical Applications

The Scavenger Receptor SREC-I Cooperates with Toll-Like Receptors to Trigger Inflammatory Innate Immune Responses

(2016) Ayesha Murshid et al.   Frontiers in Immunology

Targeting myeloid cells using nanoparticles to improve cancer immunotherapy

(2015) Zohreh Amoozgar et al.   ADVANCED DRUG DELIVERY REVIEWS

Tailoring Cellular Uptake of Gold Nanoparticles Via the Hydrophilic-to-Hydrophobic Ratio of their (Co)polymer Coating

(2015) Zhiyue Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Protein Corona of Nanoparticles: Distinct Proteins Regulate the Cellular Uptake

(2015) Sandra Ritz et al.   BIOMACROMOLECULES

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Multivalent Nanomaterials: Learning from Vaccines and Progressing to Antigen-Specific Immunotherapies

(2015) Brittany L. Hartwell et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Stealth Effect of Biomolecular Corona on Nanoparticle Uptake by Immune Cells

(2015) Giulio Caracciolo et al.   LANGMUIR

Mapping protein binding sites on the biomolecular corona of nanoparticles

(2015) Philip M. Kelly et al.   Nature Nanotechnology

Nanoparticle–Cell Interactions: Molecular Structure of the Protein Corona and Cellular Outcomes

(2014) Candace C. Fleischer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Cryptic Epitopes of Albumin Determine Mononuclear Phagocyte System Clearance of Nanomaterials

(2014) Gysell M. Mortimer et al.   ACS Nano

Protein Interactions with Polymer Coatings and Biomaterials

(2014) Qiang Wei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polyethylene Glycol Backfilling Mitigates the Negative Impact of the Protein Corona on Nanoparticle Cell Targeting

(2014) Qin Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum

(2014) Lutz Nuhn et al.   BIOMACROMOLECULES

Phagocytosis: receptors, signal integration, and the cytoskeleton

(2014) Spencer A. Freeman et al.   IMMUNOLOGICAL REVIEWS

The CD47-SIRP  signalling system: its physiological roles and therapeutic application

(2014) Y. Murata et al.   JOURNAL OF BIOCHEMISTRY

Targeted Delivery of Mycobacterial Antigens to Human Dendritic Cells via Siglec-7 Induces Robust T Cell Activation

(2014) Norihito Kawasaki et al.   JOURNAL OF IMMUNOLOGY

Induction of Potent CD8 T Cell Cytotoxicity by Specific Targeting of Antigen to Cross-Presenting Dendritic Cells In Vivo via Murine or Human XCR1

(2014) Evelyn Hartung et al.   JOURNAL OF IMMUNOLOGY

Biological Barriers and Current Strategies for Modifying Nanoparticle Bioavailability

(2014) Andrew M. Prantner et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Effect of Charge Regulation and Ion–Dipole Interactions on the Selectivity of Protein–Nanoparticle Binding

(2014) Fernando Luís Barroso da Silva et al.   LANGMUIR

Personalized protein coronas: a “key” factor at the nanobiointerface

(2014) Mohammad J. Hajipour et al.   Biomaterials Science

Harnessing Human Cross-Presenting CLEC9A+XCR1+ Dendritic Cells for Immunotherapy

(2014) Kirsteen M. Tullett et al.   Frontiers in Immunology

Differential Roles of the Protein Corona in the Cellular Uptake of Nanoporous Polymer Particles by Monocyte and Macrophage Cell Lines

(2013) Yan Yan et al.   ACS Nano

Recent progress concerning CpG DNA and its use as a vaccine adjuvant

(2013) Hidekazu Shirota et al.   Expert Review of Vaccines

Neutrophil cell surface receptors and their intracellular signal transduction pathways

(2013) Krisztina Futosi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Tethered PEG Crowdedness Determining Shape and Blood Circulation Profile of Polyplex Micelle Gene Carriers

(2013) Theofilus A. Tockary et al.   MACROMOLECULES

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology

(2013) Stefan Tenzer et al.   Nature Nanotechnology

CD36 Contributes to Malaria Parasite-Induced Pro-Inflammatory Cytokine Production and NK and T Cell Activation by Dendritic Cells

(2013) Nagaraj M. Gowda et al.   PLoS One

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Proteins: Biosafety and Bioapplication of Nanomaterials by Designing Protein-Nanoparticle Interactions (Small 9-10/2013)

(2013) Sheng-Tao Yang et al.   Small

The Effect of Nanoparticle Polyethylene Glycol Surface Density on Ligand-Directed Tumor Targeting Studied in Vivo by Dual Modality Imaging

(2012) Sjoerd Hak et al.   ACS Nano

Effects of surface functional groups on the formation of nanoparticle-protein corona

(2012) R. Podila et al.   APPLIED PHYSICS LETTERS

Recognition of Dextran–Superparamagnetic Iron Oxide Nanoparticle Conjugates (Feridex) via Macrophage Scavenger Receptor Charged Domains

(2012) Ying Chao et al.   BIOCONJUGATE CHEMISTRY

Internalization and endosomal degradation of receptor-bound antigens regulate the efficiency of cross presentation by human dendritic cells

(2012) B. Chatterjee et al.   BLOOD

Significance of cell “observer” and protein source in nanobiosciences

(2012) Sophie Laurent et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Interaction of Polyethyleneimine-Functionalized ZnO Nanoparticles with Bovine Serum Albumin

(2012) Soumyananda Chakraborti et al.   LANGMUIR

Complex encounters: nanoparticles in whole blood and their uptake into different types of white blood cells

(2012) Daniela Baumann et al.   Nanomedicine

DEC-205 is a cell surface receptor for CpG oligonucleotides

(2012) M. H. Lahoud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking

(2012) Xiaopin Duan et al.   Small

Eaten alive! Cell death by primary phagocytosis: ‘phagoptosis’

(2012) Guy C. Brown et al.   TRENDS IN BIOCHEMICAL SCIENCES

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

(2011) Carl D. Walkey et al.   CHEMICAL SOCIETY REVIEWS

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Contrasting Effect of Gold Nanoparticles and Nanorods with Different Surface Modifications on the Structure and Activity of Bovine Serum Albumin

(2011) Soumyananda Chakraborty et al.   LANGMUIR

The orchestration of cellular and humoral responses is facilitated by divergent intracellular antigen trafficking in nanoparticle-based therapeutic vaccine

(2011) Hua Yue et al.   PHARMACOLOGICAL RESEARCH

Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics

(2011) Matthias Barz et al.   Polymer Chemistry

Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives

(2010) Katrin Knop et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scavenger Receptors Mediate Cellular Uptake of Polyvalent Oligonucleotide-Functionalized Gold Nanoparticles

(2010) Pinal C. Patel et al.   BIOCONJUGATE CHEMISTRY

Nanotechnology-based manipulation of dendritic cells for enhanced immunotherapy strategies

(2010) Rebecca Klippstein et al.   Nanomedicine-Nanotechnology Biology and Medicine

Interaction of Gold Nanoparticles with Common Human Blood Proteins

(2009) Silvia H. De Paoli Lacerda et al.   ACS Nano

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

The Human Cancer Antigen Mesothelin Is More Efficiently Presented to the Mouse Immune System when Targeted to the DEC-205/CD205 Receptor on Dendritic Cells

(2009) Bei Wang et al.   Annals of the New York Academy of Sciences

Fc-DIRECTED ANTIBODY CONJUGATION OF MAGNETIC NANOPARTICLES FOR ENHANCED MOLECULAR TARGETING

(2009) ROBABEH REZAEIPOOR et al.   Journal of Innovative Optical Health Sciences

Mannose-targeted systems for the delivery of therapeutics

(2008) Juan M Irache et al.   Expert Opinion on Drug Delivery

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

(2008) Olivier Joffre et al.   IMMUNOLOGICAL REVIEWS

Role of Particle Size in Phagocytosis of Polymeric Microspheres

(2008) Julie A. Champion et al.   PHARMACEUTICAL RESEARCH

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA