Analysis of anti-malarial resistance markers in pfmdr1 and pfcrt across Southeast Asia in the Tracking Resistance to Artemisinin Collaboration

Declining Efficacy of Artemisinin Combination Therapy AgainstP. FalciparumMalaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

(2016) Aung Pyae Phyo et al.   CLINICAL INFECTIOUS DISEASES

Dihydroartemisinin–piperaquine resistance in Plasmodium falciparum malaria in Cambodia: a multisite prospective cohort study

(2016) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar

(2016) Aye A. Win et al.   MALARIA JOURNAL

Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies

(2016) M. Isabel Veiga et al.   Nature Communications

Genomic epidemiology of artemisinin resistant malaria

(2016)   eLife

Ex VivoDrug Susceptibility Testing and Molecular Profiling of Clinical Plasmodium falciparum Isolates from Cambodia from 2008 to 2013 Suggest Emerging Piperaquine Resistance

(2015) Suwanna Chaorattanakawee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Artemisinin Resistance at the China-Myanmar Border and Association with Mutations in the K13 Propeller Gene

(2015) Zenglei Wang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Decreasingpfmdr1Copy Number Suggests that Plasmodium falciparum in Western Cambodia Is RegainingIn VitroSusceptibility to Mefloquine

(2015) Pharath Lim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker

(2015) Kyaw M Tun et al.   LANCET INFECTIOUS DISEASES

Balancing drug resistance and growth rates via compensatory mutations in thePlasmodium falciparumchloroquine resistance transporter

(2015) Ines Petersen et al.   MOLECULAR MICROBIOLOGY

Genetic architecture of artemisinin-resistant Plasmodium falciparum

(2015) Olivo Miotto et al.   NATURE GENETICS

Polymorphisms in Plasmodium falciparum Chloroquine Resistance Transporter and Multidrug Resistance 1 Genes: Parasite Risk Factors That Affect Treatment Outcomes for P. falciparum Malaria After Artemether-Lumefantrine and Artesunate-Amodiaquine

(2014) Meera Venkatesan et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Role ofPfmdr1inIn VitroPlasmodium falciparum Susceptibility to Chloroquine, Quinine, Monodesethylamodiaquine, Mefloquine, Lumefantrine, and Dihydroartemisinin

(2014) Nathalie Wurtz et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia

(2014) Shannon Takala-Harrison et al.   JOURNAL OF INFECTIOUS DISEASES

Distribution of pfmdr1 polymorphisms in Plasmodium falciparum isolated from Southern Thailand

(2014) Mathirut Mungthin et al.   MALARIA JOURNAL

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Dihydroartemisinin–Piperaquine Failure in Cambodia

(2014) David L. Saunders et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ex VivoSusceptibility of Plasmodium falciparum to Antimalarial Drugs in Western, Northern, and Eastern Cambodia, 2011-2012: Association with Molecular Markers

(2013) Pharath Lim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Temporal trends of molecular markers associated with artemether-lumefantrine tolerance/resistance in Bagamoyo district, Tanzania

(2013) Maja Malmberg et al.   MALARIA JOURNAL

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia

(2013) Olivo Miotto et al.   NATURE GENETICS

Malaria Burden and Artemisinin Resistance in the Mobile and Migrant Population on the Thai–Myanmar Border, 1999–2011: An Observational Study

(2013) Verena I. Carrara et al.   PLOS MEDICINE

Efficacy of Dihydroartemisinin-Piperaquine for Treatment of Uncomplicated Plasmodium falciparum and Plasmodium vivax in Cambodia, 2008 to 2010

(2012) R. Leang et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

(2012) Aung Pyae Phyo et al.   LANCET

Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study

(2012) Chanaki Amaratunga et al.   LANCET INFECTIOUS DISEASES

Molecular surveillance for drug-resistant Plasmodium falciparum in clinical and subclinical populations from three border regions of Burma/Myanmar: cross-sectional data and a systematic review of resistance studies

(2012) Tyler Brown et al.   MALARIA JOURNAL

The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam

(2012) Nguyen Thanh et al.   MALARIA JOURNAL

Using CF11 cellulose columns to inexpensively and effectively remove human DNA from Plasmodium falciparum-infected whole blood samples

(2012) Meera Venkatesan et al.   MALARIA JOURNAL

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

Novel Polymorphisms in Plasmodium falciparum ABC Transporter Genes Are Associated with Major ACT Antimalarial Drug Resistance

(2011) Maria Isabel Veiga et al.   PLoS One

Association Between the pfmdr1 Gene and In Vitro Artemether and Lumefantrine Sensitivity in Thai Isolates of Plasmodium falciparum

(2010) Mathirut Mungthin et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

A Phase III, Randomized, Non-Inferiority Trial to Assess the Efficacy and Safety of Dihydroartemisinin-Piperaquine in Comparison with Artesunate-Mefloquine in Patients with Uncomplicated Plasmodium falciparum Malaria in Southern Laos

(2010) Mayfong Mayxay et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Exploring the Contribution of Candidate Genes to Artemisinin Resistance in Plasmodium falciparum

(2010) M. Imwong et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Amodiaquine Resistance in Plasmodium falciparum Malaria in Afghanistan Is Associated with the pfcrt SVMNT Allele at Codons 72 to 76

(2010) K. Beshir et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites

(2010) Paul Hunt et al.   BMC GENOMICS

Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: an open-label randomised trial

(2010) Frank Smithuis et al.   LANCET INFECTIOUS DISEASES

The patterns of mutation and amplification of Plasmodium falciparum pfcrt and pfmdr1 genes in Thailand during the year 1988 to 2003

(2010) Mathirut Mungthin et al.   PARASITOLOGY RESEARCH

Plasmodium falciparum pfmdr1 Amplification, Mefloquine Resistance, and Parasite Fitness

(2009) P. Preechapornkul et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia

(2009) Pharath Lim et al.   MALARIA JOURNAL

Artemisinin-Resistant Malaria in Asia

(2009) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Changes in the Treatment Responses to Artesunate-Mefloquine on the Northwestern Border of Thailand during 13 Years of Continuous Deployment

(2009) Verena Ilona Carrara et al.   PLoS One

Geographic patterns ofPlasmodium falciparumdrug resistance distinguished by differential responses to amodiaquine and chloroquine

(2009) Juliana Martha Sá et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gene copy number and malaria biology

(2009) Tim J.C. Anderson et al.   TRENDS IN PARASITOLOGY

Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicatedPlasmodium falciparummalaria in central Vietnam

(2009) Nguyen Xuan Thanh et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH