Integrated serum pharmacochemistry and metabolomics reveal potential effective components and mechanisms of Shengjiang Xiexin decoction in the treatment of Clostridium difficile infection

Improvement of the Gut Microbiota In Vivo by a Short-Chain Fatty Acids-Producing Strain Lactococcus garvieae CF11

(2022) Shuting Fang et al.   Processes

Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats

(2021) Bolin Li et al.   LIFE SCIENCES

Ginger and 6‐gingerol prevent lipopolysaccharide‐induced intestinal barrier damage and liver injury in mice

(2021) Xiao‐Xuan Guo et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Prevention of Infection due to Clostridium (Clostridioides) difficile

(2021) Amar Krishna et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas

(2020) Jun Liu et al.   NATURE MEDICINE

Diarrhoeal events can trigger long-term Clostridium difficile colonization with recurrent blooms

(2020) David VanInsberghe et al.   Nature Microbiology

Efficacy and safety of Shengjiang Xiexin decoction in prophylaxis of chemotherapy-related diarrhea in small cell lung cancer patients: study protocol for a multicenter randomized controlled trial

(2020) Chao Deng et al.   Trials

Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis

(2020) Heng Li et al.   Cell Death & Disease

Multi-level consistent changes of the ECM pathway identified in a typical keratoconus twin’s family by multi-omics analysis

(2020) Xiao-dan Hao et al.   Orphanet Journal of Rare Diseases

Chinmedomics, a new strategy for evaluating the therapeutic efficacy of herbal medicines

(2020) Ying Han et al.   PHARMACOLOGY & THERAPEUTICS

Fructus Gardeniae-induced gastrointestinal injury was associated with the inflammatory response mediated by the disturbance of vitamin B6, phenylalanine, arachidonic acid, taurine and hypotaurine metabolism

(2019) Jing Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

6-Gingerol abates benzo[a]pyrene-induced colonic injury via suppression of oxido-inflammatory stress responses in BALB/c mice

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Simulated Weightlessness Perturbs the Intestinal Metabolomic Profile of Rats

(2019) Mingliang Jin et al.   Frontiers in Physiology

Best practices for analysing microbiomes

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Modulation of gut microbiota and gut-generated metabolites by bitter melon results in improvement in the metabolic status in high fat diet-induced obese rats

(2018) Juan Bai et al.   Journal of Functional Foods

18β-Glycyrrhetinic acid protects against alpha-naphthylisothiocyanate-induced cholestasis through activation of the Sirt1/FXR signaling pathway

(2018) Shou-yan Wu et al.   ACTA PHARMACOLOGICA SINICA

Moxibustion treatment modulates the gut microbiota and immune function in a dextran sulphate sodium-induced colitis rat model

(2018) Qin Qi et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Preventive Effects of a Chinese Herbal Formula, Shengjiang Xiexin Decoction, on Irinotecan-Induced Delayed-Onset Diarrhea in Rats

(2017) Chao Deng et al.   Evidence-based Complementary and Alternative Medicine

Ginger Extract Suppresses Inflammatory Response and Maintains Barrier Function in Human Colonic Epithelial Caco-2 Cells Exposed to Inflammatory Mediators

(2017) Yunyoung Kim et al.   JOURNAL OF FOOD SCIENCE

Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample preparation and LC-MS/MS

(2017) Huanyu Guan et al.   RSC Advances

Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity

(2017) Huan-yu Guan et al.   Frontiers in Pharmacology

Approaches to establish Q-markers for the quality standards of traditional Chinese medicines

(2017) Wenzhi Yang et al.   Acta Pharmaceutica Sinica B

Simultaneous determination of 14 active constituents of Shengjiang Xiexin decoction using ultrafast liquid chromatography coupled with electrospray ionization tandem mass spectrometry

(2017) Gang Peng et al.   Acta Pharmaceutica Sinica B

Traditional Chinese Medicine QPYF as Preventive Treatment forClostridium difficileAssociated Diarrhea in a Mouse Model

(2016) Guo Ya-Nan et al.   Evidence-based Complementary and Alternative Medicine

Clostridium difficile colitis: pathogenesis and host defence

(2016) Michael C. Abt et al.   NATURE REVIEWS MICROBIOLOGY

Berberine Blocks the Relapse of Clostridium difficile Infection in C57BL/6 Mice after Standard Vancomycin Treatment

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Rapid spread of Clostridium difficile NAP1/027/ST1 in Chile confirms the emergence of the epidemic strain in Latin America

(2015) C. AGUAYO et al.   EPIDEMIOLOGY AND INFECTION

Clostridium difficile Infection

(2015) Paul Feuerstadt   Clinical and Translational Gastroenterology

Role of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile

(2014) Robert A. Britton et al.   GASTROENTEROLOGY

Fidaxomicin versus Vancomycin forClostridium difficileInfection

(2011) Thomas J. Louie et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preventive effect of Coptis chinensis and berberine on intestinal injury in rats challenged with lipopolysaccharides

(2010) Qian Zhang et al.   FOOD AND CHEMICAL TOXICOLOGY

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics

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