Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity

Preventive Effects of a Chinese Herbal Formula, Shengjiang Xiexin Decoction, on Irinotecan-Induced Delayed-Onset Diarrhea in Rats

(2017) Chao Deng et al.   Evidence-based Complementary and Alternative Medicine

Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample preparation and LC-MS/MS

(2017) Huanyu Guan et al.   RSC Advances

Development and validation of an UPLC–MS/MS method for the quantification of irinotecan, SN-38 and SN-38 glucuronide in plasma, urine, feces, liver and kidney: Application to a pharmacokinetic study of irinotecan in rats

(2016) Sumit Basu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Potential drug interactions associated with glycyrrhizin and glycyrrhetinic acid

(2015) Xinchi Feng et al.   DRUG METABOLISM REVIEWS

Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice

(2015) Ling-Lei Kong et al.   Scientific Reports

Therapeutic Targeting of CPT-11 Induced Diarrhea: A Case for Prophylaxis

(2013) Umang Swami et al.   CURRENT DRUG TARGETS

Strategies and Techniques for Multi-Component Drug Design from Medicinal Herbs and Traditional Chinese Medicine

(2012) Yi Wang et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Effect of genistein, a natural soy isoflavone, on the pharmacokinetics and intestinal toxicity of irinotecan hydrochloride in rats

(2012) Tomoharu Yokooji et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Breast Cancer Resistance Protein (BCRP) and Sulfotransferases Contribute Significantly to the Disposition of Genistein in Mouse Intestine

(2010) Wei Zhu et al.   AAPS Journal

Evaluation of the Flavonoid Oroxylin A as an Inhibitor of P-Glycoprotein-Mediated Cellular Efflux

(2009) Woon Jung Go et al.   JOURNAL OF NATURAL PRODUCTS

Effect of P-glycoprotein inhibitor, verapamil, on oral bioavailability and pharmacokinetics of irinotecan in rats

(2008) Tripta Bansal et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES