Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas
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Title
Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug–metabolite atlas
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 26, Issue 1, Pages 110-117
Publisher
Springer Science and Business Media LLC
Online
2020-01-14
DOI
10.1038/s41591-019-0722-x
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Note: Only part of the references are listed.- Association of Triglyceride-Lowering LPL Variants and LDL-C–Lowering LDLR Variants With Risk of Coronary Heart Disease
- (2019) Brian A. Ference et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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- (2019) Ari V. Ahola-Olli et al. DIABETOLOGIA
- Relationship between gut microbiota and circulating metabolites in population-based cohorts
- (2019) Dina Vojinovic et al. Nature Communications
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- (2018) Sven J. van der Lee et al. Alzheimers & Dementia
- Proton Pump Inhibitor Initiation and Withdrawal affects Gut Microbiota and Readmission Risk in Cirrhosis
- (2018) Jasmohan S Bajaj et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Cardiovascular Metabolomics
- (2018) Robert W. McGarrah et al. CIRCULATION RESEARCH
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- (2018) Michael V. Holmes et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
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- (2018) Naomi R. Wray et al. NATURE GENETICS
- Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
- (2018) Lesley Hoyles et al. NATURE MEDICINE
- The MR-Base platform supports systematic causal inference across the human phenome
- (2018) Gibran Hemani et al. eLife
- Blood metabolomic measures associate with present and future glycemic control in type 2 diabetes
- (2018) Leen M ‘t Hart et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Metabolomics for Prediction of Relapse in Graves' Disease: Observational Pilot Study
- (2018) Tristan Struja et al. Frontiers in Endocrinology
- The Rotterdam Study: 2018 update on objectives, design and main results
- (2017) M. Arfan Ikram et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention
- (2017) Ruixin Liu et al. NATURE MEDICINE
- The Hoorn Diabetes Care System (DCS) cohort. A prospective cohort of persons with type 2 diabetes treated in primary care in the Netherlands
- (2017) Amber AWA van der Heijden et al. BMJ Open
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- (2016) Deepak Voora et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase
- (2016) Peter Würtz et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Pharmacometabolomic signature links simvastatin therapy and insulin resistance
- (2016) Mona Elbadawi-Sidhu et al. Metabolomics
- Human gut microbes impact host serum metabolome and insulin sensitivity
- (2016) Helle Krogh Pedersen et al. NATURE
- Emerging applications of metabolomics in drug discovery and precision medicine
- (2016) David S. Wishart NATURE REVIEWS DRUG DISCOVERY
- Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA
- (2016) Johannes Kettunen et al. Nature Communications
- ‘RE:fine drugs’: an interactive dashboard to access drug repurposing opportunities
- (2016) Soheil Moosavinasab et al. Database-The Journal of Biological Databases and Curation
- Novel Protein Glycan Side-Chain Biomarker and Risk of Incident Type 2 Diabetes Mellitus
- (2015) A. O. Akinkuolie et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics
- (2015) Pasi Soininen et al. Circulation-Cardiovascular Genetics
- Effects of Metformin on Metabolite Profiles and LDL Cholesterol in Patients With Type 2 Diabetes
- (2015) Tao Xu et al. DIABETES CARE
- Proton pump inhibitors affect the gut microbiome
- (2015) Floris Imhann et al. GUT
- Proton pump inhibitors alter the composition of the gut microbiota
- (2015) Matthew A Jackson et al. GUT
- Presence of diabetes mellitus and steatosis is associated with liver stiffness in a general population: The Rotterdam study
- (2015) Edith M. Koehler et al. HEPATOLOGY
- Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels
- (2015) Harmen H. M. Draisma et al. Nature Communications
- Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites
- (2015) Alison N. Thorburn et al. Nature Communications
- Cohort profile: LifeLines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics
- (2015) Ettje F Tigchelaar et al. BMJ Open
- Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Cardiovascular Epidemiology and Genetics
- (2015) Pasi Soininen et al. Circulation-Cardiovascular Genetics
- HDL particle number and size as predictors of cardiovascular disease
- (2015) Anatol Kontush Frontiers in Pharmacology
- Conducting Meta-Analyses inRwith themetaforPackage
- (2015) Wolfgang Viechtbauer Journal of Statistical Software
- Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function
- (2014) Jasmohan S. Bajaj et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
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- (2014) Stephen M. Rappaport et al. ENVIRONMENTAL HEALTH PERSPECTIVES
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- (2014) Elisabeth Altmaier et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities
- (2014) Miranda T. Schram et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
- Alterations of the human gut microbiome in liver cirrhosis
- (2014) Nan Qin et al. NATURE
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- (2014) Mark Mapstone et al. NATURE MEDICINE
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- (2014) Krista Fischer et al. PLOS MEDICINE
- A Novel Protein Glycan Biomarker and Future Cardiovascular Disease Events
- (2014) Akintunde O. Akinkuolie et al. Journal of the American Heart Association
- The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection
- (2013) Renée de Mutsert et al. EUROPEAN JOURNAL OF EPIDEMIOLOGY
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- (2011) Karsten Suhre et al. NATURE
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- (2011) Thomas J Wang et al. NATURE MEDICINE
- Effect of low doses of n-3 fatty acids on cardiovascular diseases in 4,837 post-myocardial infarction patients: Design and baseline characteristics of the Alpha Omega Trial
- (2010) Johanna M. Geleijnse et al. AMERICAN HEART JOURNAL
- Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study
- (2010) Rima Kaddurah-Daouk et al. Metabolomics
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- (2010) Michael Inouye et al. Molecular Systems Biology
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- (2009) Alex J Mitchell et al. LANCET
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- (2008) Brenda W.J.H. Penninx et al. INTERNATIONAL JOURNAL OF METHODS IN PSYCHIATRIC RESEARCH
- Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology
- (2007) Debbie A. Lawlor et al. STATISTICS IN MEDICINE
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