Autoantibodies, complement and type I interferon as biomarkers for personalized medicine in SLE

The proteasome inhibitior bortezomib depletes plasma cells and ameliorates clinical manifestations of refractory systemic lupus erythematosus

(2015) Tobias Alexander et al.   ANNALS OF THE RHEUMATIC DISEASES

A Phase II study of the efficacy and safety of rontalizumab (rhuMAb interferon-α) in patients with systemic lupus erythematosus (ROSE)

(2015) Kenneth C Kalunian et al.   ANNALS OF THE RHEUMATIC DISEASES

Drug-induced lupus

(2015) Robert L Rubin   Expert Opinion On Drug Safety

Safety and Efficacy of Belimumab to Treat Systemic Lupus Erythematosus in Academic Clinical Practices

(2015) J. S. Hui-Yuen et al.   JOURNAL OF RHEUMATOLOGY

Monocyte CD64 expression as a novel biomarker for the disease activity of systemic lupus erythematosus

(2015) A Kikuchi-Taura et al.   LUPUS

Drug-induced lupus: Including anti-tumour necrosis factor and interferon induced

(2014) S Araújo-Fernández et al.   LUPUS

IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus

(2012) Thomas Rose et al.   ANNALS OF THE RHEUMATIC DISEASES

Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response

(2012) Ronald F van Vollenhoven et al.   ANNALS OF THE RHEUMATIC DISEASES

Belimumab reduces autoantibodies, normalizes low complement levels, and reduces select B cell populations in patients with systemic lupus erythematosus

(2012) William Stohl et al.   ARTHRITIS AND RHEUMATISM

Are anti-nucleosome antibodies a better diagnostic marker than anti-dsDNA antibodies for systemic lupus erythematosus? A systematic review and a study of metanalysis

(2012) Nicola Bizzaro et al.   AUTOIMMUNITY REVIEWS

Monogenic forms of systemic lupus erythematosus: new insights into SLE pathogenesis

(2012) Alexandre Belot et al.   Pediatric Rheumatology

Use of type I interferon-inducible mRNAs as pharmacodynamic markers and potential diagnostic markers in trials with sifalimumab, an anti-IFNα antibody, in systemic lupus erythematosus

(2012) Yihong Yao et al.   ARTHRITIS RESEARCH & THERAPY

Association of endogenous anti-interferon-α autoantibodies with decreased interferon-pathway and disease activity in patients with systemic lupus erythematosus

(2011) Alyssa M. Morimoto et al.   ARTHRITIS AND RHEUMATISM

Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

(2011) A. Kuznik et al.   JOURNAL OF IMMUNOLOGY

Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

(2011) Falk Hiepe et al.   Nature Reviews Rheumatology

Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus

(2011) Fidan Barkhudarova et al.   ARTHRITIS RESEARCH & THERAPY

Anti-dsDNA-NcX ELISA: dsDNA-loaded nucleosomes improve diagnosis and monitoring of disease activity in systemic lupus erythematosus

(2011) Robert Biesen et al.   ARTHRITIS RESEARCH & THERAPY

Erythrocyte C3d and C4d for monitoring disease activity in systemic lupus erythematosus

(2010) Amy H. Kao et al.   ARTHRITIS AND RHEUMATISM

Type I interferon: friend or foe?

(2010) Giorgio Trinchieri   JOURNAL OF EXPERIMENTAL MEDICINE

Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus

(2010) Yi Li et al.   ARTHRITIS RESEARCH & THERAPY

HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus

(2009) A M Jacobi et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: A validation study

(2009) Jason W. Bauer et al.   ARTHRITIS AND RHEUMATISM

Enhanced expression of interferon-inducible protein-10 correlates with disease activity and clinical manifestations in systemic lupus erythematosus

(2009) K. O. Kong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Upregulated BclGL expression enhances apoptosis of peripheral blood CD4+ T lymphocytes in patients with systemic lupus erythematosus

(2009) Na Luo et al.   CLINICAL IMMUNOLOGY

Longitudinal expression of type I interferon responsive genes in systemic lupus erythematosus

(2009) M Petri et al.   LUPUS

Lack of association between the interferon-  signature and longitudinal changes in disease activity in systemic lupus erythematosus

(2008) C Landolt-Marticorena et al.   ANNALS OF THE RHEUMATIC DISEASES

Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus

(2008) Robert Biesen et al.   ARTHRITIS AND RHEUMATISM

Autoantibodies and neuropsychiatric events at the time of systemic lupus erythematosus diagnosis: Results from an international inception cohort study

(2008) J. G. Hanly et al.   ARTHRITIS AND RHEUMATISM

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

(2008) T. Alexander et al.   BLOOD