Genome-wide association meta-analysis identifies five novel loci for age-related hearing impairment

The risk of cognitive impairment associated with hearing function in older adults: a pooled analysis of data from eleven studies

(2018) Jing Yuan et al.   Scientific Reports

Type I interferon pathway in CNS homeostasis and neurological disorders

(2017) Thomas Blank et al.   GLIA

A nonsynonymous mutation in the WFS1 gene in a Finnish family with age-related hearing impairment

(2017) Laura Kytövuori et al.   HEARING RESEARCH

Broadening the phenotype of DFNB28: Mutations in TRIOBP are associated with moderate, stable hereditary hearing impairment

(2017) Mieke Wesdorp et al.   HEARING RESEARCH

Next-generation sequencing identifies three novel missense variants in ILDR1 and MYO6 genes in an Iranian family with hearing loss with review of the literature

(2017) Farah Talebi et al.   INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY

Global hearing health care: new findings and perspectives

(2017) Blake S Wilson et al.   LANCET

Functional mapping and annotation of genetic associations with FUMA

(2017) Kyoko Watanabe et al.   Nature Communications

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

(2017) Michael R. Bowl et al.   Nature Communications

Identification of a novel frameshift mutation in the ILDR1 gene in a UAE family, mutations review and phenotype genotype correlation

(2017) Abdelaziz Tlili et al.   PLoS One

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

(2016) Jie Zheng et al.   BIOINFORMATICS

A comprehensive catalogue of the coding and non-coding transcripts of the human inner ear

(2016) Isabelle Schrauwen et al.   HEARING RESEARCH

Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation

(2016) Thomas J Hoffmann et al.   NATURE GENETICS

A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records

(2016) Thomas J. Hoffmann et al.   PLoS Genetics

The European GWAS-identified risk SNP rs457717 within IQGAP2 is not associated with age-related hearing impairment in Han male Chinese population

(2015) Huajie Luo et al.   EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY

Gene Expression by Mouse Inner Ear Hair Cells during Development

(2015) D. I. Scheffer et al.   JOURNAL OF NEUROSCIENCE

Downsloping High-Frequency Hearing Loss Due to Inner Ear Tricellular Tight Junction Disruption by a Novel ILDR1 Mutation in the Ig-Like Domain

(2015) Nayoung K. D. Kim et al.   PLoS One

SHIELD: an integrative gene expression database for inner ear research

(2015) Jun Shen et al.   Database-The Journal of Biological Databases and Curation

MAGMA: Generalized Gene-Set Analysis of GWAS Data

(2015) Christiaan A. de Leeuw et al.   PLoS Computational Biology

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Hearing Impairment Prevalence and Associated Risk Factors in the Hispanic Community Health Study/Study of Latinos

(2015) Karen J. Cruickshanks et al.   JAMA Otolaryngology-Head & Neck Surgery

ILDR1 deficiency causes degeneration of cochlear outer hair cells and disrupts the structure of the organ of Corti: a mouse model for human DFNB42

(2015) Q. Sang et al.   Biology Open

The global burden of disabling hearing impairment: a call to action

(2014) Bolajoko O Olusanya et al.   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Genome-wide association analysis demonstrates the highly polygenic character of age-related hearing impairment

(2014) Erik Fransen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

ILDR1: Novel mutation and a rare cause of congenital deafness in the Saudi Arabian population

(2014) Khushnooda Ramzan et al.   European Journal of Medical Genetics

The Mouse as a Model for Age-Related Hearing Loss - A Mini-Review

(2014) Michael R. Bowl et al.   GERONTOLOGY

Salt-inducible kinase 3, SIK3, is a new gene associated with hearing

(2014) Lisa E. Wolber et al.   HUMAN MOLECULAR GENETICS

Characterization of Transcriptomes of Cochlear Inner and Outer Hair Cells

(2014) H. Liu et al.   JOURNAL OF NEUROSCIENCE

Quality control and conduct of genome-wide association meta-analyses

(2014) Thomas W Winkler et al.   Nature Protocols

Hearing Impairment Associated With Depression in US Adults, National Health and Nutrition Examination Survey 2005-2010

(2014) Chuan-Ming Li et al.   JAMA Otolaryngology-Head & Neck Surgery

Estimation and Partition of Heritability in Human Populations Using Whole-Genome Analysis Methods

(2013) Anna A.E. Vinkhuyzen et al.   Annual Review of Genetics

Progressive hereditary hearing impairment caused by a MYO6 mutation resembles presbyacusis

(2013) A.M.M. Oonk et al.   HEARING RESEARCH

Heritability of Hearing Loss

(2012) Ellen Kvestad et al.   EPIDEMIOLOGY

Hearing Ability with Age in Northern European Women: A New Web-Based Approach to Genetic Studies

(2012) Lisa E. Wolber et al.   PLoS One

The impact of hearing loss on the quality of life of elderly adults

(2012) Andrea Ciorba et al.   Clinical Interventions in Aging

Loss-of-Function Mutations of ILDR1 Cause Autosomal-Recessive Hearing Impairment DFNB42

(2011) Guntram Borck et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Association of Skin Color, Race/Ethnicity, and Hearing Loss Among Adults in the USA

(2011) Frank R. Lin et al.   JARO-JOURNAL OF THE ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGY

Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways

(2011) G. Girotto et al.   JOURNAL OF MEDICAL GENETICS

Developmental Profiling of Spiral Ganglion Neurons Reveals Insights into Auditory Circuit Assembly

(2011) C. C. Lu et al.   JOURNAL OF NEUROSCIENCE

Protective Role of Hydrogen Sulfide against Noise-Induced Cochlear Damage: A Chronic Intracochlear Infusion Model

(2011) Xu Li et al.   PLoS One

Genomic Duplication and Overexpression of TJP2/ZO-2 Leads to Altered Expression of Apoptosis Genes in Progressive Nonsyndromic Hearing Loss DFNA51

(2010) Tom Walsh et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GCTA: A Tool for Genome-wide Complex Trait Analysis

(2010) Jian Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

METAL: fast and efficient meta-analysis of genomewide association scans

(2010) C. J. Willer et al.   BIOINFORMATICS

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

(2010) Shin-ichiro Kitajiri et al.   CELL

A genome-wide association study for age-related hearing impairment in the Saami

(2010) Lut Van Laer et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

(2009) Bruce M. Psaty et al.   Circulation-Cardiovascular Genetics

Prevalence of Hearing Loss and Differences by Demographic Characteristics Among US AdultsData From the National Health and Nutrition Examination Survey, 1999-2004

(2008) Yuri Agrawal   ARCHIVES OF INTERNAL MEDICINE

GRM7 variants confer susceptibility to age-related hearing impairment

(2008) Rick A. Friedman et al.   HUMAN MOLECULAR GENETICS

 II- V spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells

(2008) K. Legendre et al.   JOURNAL OF CELL SCIENCE

Presbycusis: A human temporal bone study of individuals with flat audiometric patterns of hearing loss using a new method to quantify stria vascularis volume

(2003) Erik G. Nelson et al.   LARYNGOSCOPE