Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics
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Title
Progesterone Signaling and Uterine Fibroid Pathogenesis; Molecular Mechanisms and Potential Therapeutics
Authors
Keywords
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Journal
Cells
Volume 12, Issue 8, Pages 1117
Publisher
MDPI AG
Online
2023-04-10
DOI
10.3390/cells12081117
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Note: Only part of the references are listed.- HOXA10 improves endometrial receptivity by upregulating E-cadherin
- (2022) Yin Bi et al. BIOLOGY OF REPRODUCTION
- Evaluation of marketing authorization and clinical implementation of ulipristal acetate for uterine fibroids
- (2022) Mei-An Middelkoop et al. HUMAN REPRODUCTION
- Human Myometrial and Uterine Fibroid Stem Cell-Derived Organoids for Intervening the Pathophysiology of Uterine Fibroid
- (2022) Saswati Banerjee et al. Reproductive Sciences
- A Systematic Review of Vitamin D and Fibroids: Pathophysiology, Prevention, and Treatment
- (2022) Abigail Combs et al. Reproductive Sciences
- Selective progesterone receptor modulators and reproductive health
- (2022) Lynnette K. Nieman Current Opinion in Endocrinology Diabetes and Obesity
- Reconnoitering the Therapeutic Role of Curcumin in Disease Prevention and Treatment: Lessons Learnt and Future Directions
- (2022) Bala Mohan Sivani et al. Metabolites
- Many or too many progesterone membrane receptors? Clinical implications
- (2022) Alexandra Wendler et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Berberine ameliorates ovariectomy-induced anxiety-like behaviors by enrichment in equol generating gut microbiota
- (2021) Yuan Fang et al. PHARMACOLOGICAL RESEARCH
- Pharmacokinetics, toxicological and clinical aspects of ulipristal acetate: insights into the mechanisms implicated in the hepatic toxicity
- (2021) Ricardo Jorge Dinis-Oliveira DRUG METABOLISM REVIEWS
- Assessment of the safe and efficacious dose of the selective progesterone receptor modulator vilaprisan for the treatment of patients with uterine fibroids by exposure–response modelling and simulation
- (2021) Gabriele Sutter et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Progesterone receptor-DNA methylation crosstalk regulates depletion of uterine leiomyoma stem cells: A potential therapeutic target
- (2021) Shimeng Liu et al. Stem Cell Reports
- Understanding the Impact of Uterine Fibroids on Human Endometrium Function
- (2021) Antonia Navarro et al. Frontiers in Cell and Developmental Biology
- Ameliorative Effects of Component Chinese Medicine From Curcumae Rhizoma and Sparganii Rhizoma, a Traditional Herb Pair, on Uterine Leiomyoma in a Rat Model
- (2021) Li Zhang et al. Frontiers in Public Health
- Curcumin in a tris‐based semen extender improves cryosurvival of Hariana bull spermatozoa
- (2021) Shashikant Gupta et al. ANDROLOGIA
- Comprehensive Review of Uterine Fibroids: Developmental Origin, Pathogenesis, and Treatment
- (2021) Qiwei Yang et al. ENDOCRINE REVIEWS
- Disruption of developmental programming with long-term consequences after exposure to a glyphosate-based herbicide in a rat model
- (2021) Marlise Guerrero Schimpf et al. FOOD AND CHEMICAL TOXICOLOGY
- Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study
- (2021) Giovanni Grandi et al. GYNECOLOGICAL ENDOCRINOLOGY
- The efficacy and safety of Xuefu Zhuyu Decoction combined with Mifepristone in the treatment of uterine leiomyoma: A systematic review and meta-analysis
- (2021) Shasha Shi et al. JOURNAL OF ETHNOPHARMACOLOGY
- Uterine Receptivity is Reflected by LIF Expression in the Cervix
- (2021) Yamato Fukui et al. Reproductive Sciences
- Berberine Phospholipid Is an Effective Insulin Sensitizer and Improves Metabolic and Hormonal Disorders in Women with Polycystic Ovary Syndrome: A One-Group Pretest–Post-Test Explanatory Study
- (2021) Mariangela Rondanelli et al. Nutrients
- Phytoprogestins: Unexplored Food Compounds with Potential Preventive and Therapeutic Effects in Female Diseases
- (2021) Stefania Greco et al. Nutrients
- VILAPRISAN, A NEW SELECTIVE PROGESTERONE RECEPTOR MODULATOR IN UTERINE FIBROID PHARMACOTHERAPY – WILL IT REALLY BE A BREAKTHROUGH?
- (2020) Michal Ciebiera et al. CURRENT PHARMACEUTICAL DESIGN
- Large, Non-Cavity Distorting Intramural Leiomyomas Decrease Leukemia Inhibitory Factor in the Secretory Phase Endometrium
- (2020) Bruce Pier et al. Reproductive Sciences
- Selective progesterone receptor modulators-mechanisms and therapeutic utility
- (2020) Md Soriful Islam et al. ENDOCRINE REVIEWS
- 90 YEARS OF PROGESTERONE: Selective progesterone receptor modulators in gynaecological therapies
- (2020) H O D Critchley et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis
- (2020) Maria Victoria Bariani et al. Current Opinion in Endocrinology Diabetes and Obesity
- Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers
- (2020) Yun-Ju Huang et al. Biomolecules
- The Roles of Matrix Metalloproteinases and Their Inhibitors in Human Diseases
- (2020) Griselda A Cabral-Pacheco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Sparganii Rhizoma: A review of traditional clinical application, processing, phytochemistry, pharmacology, and toxicity
- (2020) Jia Jia et al. JOURNAL OF ETHNOPHARMACOLOGY
- Safety and efficacy of the selective progesterone receptor modulator asoprisnil for heavy menstrual bleeding with uterine fibroids: pooled analysis of two 12-month, placebo-controlled, randomized trials
- (2019) E A Stewart et al. HUMAN REPRODUCTION
- Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) Hull Extract and Active Compounds Inhibit Proliferation of Primary Human Leiomyoma Cells and Protect against Sexual Hormone-Induced Mice Smooth Muscle Hyperproliferation
- (2019) Lin et al. MOLECULES
- Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation
- (2019) Po-Han Lin et al. Cancers
- Curcumin and Cancer
- (2019) Giordano et al. Nutrients
- Anti-tumor activity and linear-diarylheptanoids of herbal couple Curcumae Rhizoma-Sparganii Rhizoma and the single herbs
- (2019) Yan-Li Chang et al. JOURNAL OF ETHNOPHARMACOLOGY
- RANKL/RANK Pathway and Its Inhibitor RANK-Fc in Uterine Leiomyoma Growth
- (2018) Deborah E Ikhena et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Vitamin D supplementation guidelines
- (2018) Pawel Pludowski et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas
- (2018) James A. Simon et al. OBSTETRICS AND GYNECOLOGY
- The Flavonoid Apigenin Is a Progesterone Receptor Modulator with In Vivo Activity in the Uterus
- (2018) Matthew Dean et al. Hormones & Cancer
- Vilaprisan in women with uterine fibroids: the randomized phase 2b ASTEROID 1 study
- (2018) Linda D. Bradley et al. FERTILITY AND STERILITY
- The Role of Tumor Necrosis Factor α in the Biology of Uterine Fibroids and the Related Symptoms
- (2018) Michał Ciebiera et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2018) Shimeng Liu et al. ONCOGENE
- Real world data of 1473 patients treated with ulipristal acetate for uterine fibroids: Premya study results
- (2017) Hervé Fernandez et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Successes and failures of uterine leiomyoma drug discovery
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- Vitamin D synergizes the antiproliferative, apoptotic, antifibrotic and anti-inflammatory effects of ulipristal acetate against human uterine fibroids
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- (2016) Tung-Yueh Chuang et al. Reproductive Sciences
- Effects of isoliquiritigenin on ovarian antral follicle growth and steroidogenesis
- (2016) Sharada Mahalingam et al. REPRODUCTIVE TOXICOLOGY
- Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis
- (2016) Aymara Mas et al. STEM CELLS
- Endocrinology of uterine fibroids
- (2015) Molly B. Moravek et al. CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
- Berberine inhibits the proliferation of human uterine leiomyoma cells
- (2015) Hsiao-Li Wu et al. FERTILITY AND STERILITY
- Efficacy and safety of repeated use of ulipristal acetate in uterine fibroids
- (2015) Jacques Donnez et al. FERTILITY AND STERILITY
- Stro-1/CD44 as putative human myometrial and fibroid stem cell markers
- (2015) Aymara Mas et al. FERTILITY AND STERILITY
- Human Uterine Leiomyoma Stem/Progenitor Cells Expressing CD34 and CD49b Initiate Tumors In Vivo
- (2015) Ping Yin et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- 1,25-Dihydroxyvitamin D3 Regulates Expression of Sex Steroid Receptors in Human Uterine Fibroid Cells
- (2015) Ayman Al-Hendy et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Prescription patterns of Chinese herbal products for patients with uterine fibroid in Taiwan: A nationwide population-based study
- (2015) Hung-Rong Yen et al. JOURNAL OF ETHNOPHARMACOLOGY
- Chemical Composition, Antioxidative and Anticancer Activities of the Essential Oil: Curcumae Rhizoma–Sparganii Rhizoma, a Traditional Herb Pair
- (2015) Guan-Ling Xu et al. MOLECULES
- Dissecting the Role of Curcumin in Tumour Growth and Angiogenesis in Mouse Model of Human Breast Cancer
- (2015) Sabrina Bimonte et al. Biomed Research International
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- (2014) Lauren M. Goddard et al. CELL
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- (2014) Wenan Qiang et al. ENDOCRINOLOGY
- Long-term treatment of uterine fibroids with ulipristal acetate☆
- (2014) Jacques Donnez et al. FERTILITY AND STERILITY
- Polymorphisms in vitamin D–related genes and risk of uterine leiomyomata
- (2014) Lauren A. Wise et al. FERTILITY AND STERILITY
- Biology of the Extracellular Matrix
- (2014) Beatrice Yue JOURNAL OF GLAUCOMA
- Transforming growth factor β signaling in uterine development and function
- (2014) Qinglei Li Journal of Animal Science and Biotechnology
- 1,25-Dihydroxyvitamin D3 Reduces Extracellular Matrix-Associated Protein Expression in Human Uterine Fibroid Cells1
- (2013) Sunil K. Halder et al. BIOLOGY OF REPRODUCTION
- VEGF-A regulated by progesterone governs uterine angiogenesis and vascular remodelling during pregnancy
- (2013) Minah Kim et al. EMBO Molecular Medicine
- Progesterone Action in Endometrial Cancer, Endometriosis, Uterine Fibroids, and Breast Cancer
- (2013) J. Julie Kim et al. ENDOCRINE REVIEWS
- Complex networks of multiple factors in the pathogenesis of uterine leiomyoma
- (2013) Md Soriful Islam et al. FERTILITY AND STERILITY
- The role of angiogenic factors in fibroid pathogenesis: potential implications for future therapy
- (2013) Reshef Tal et al. HUMAN REPRODUCTION UPDATE
- Vitamin D Status in Women With Uterine Leiomyomas
- (2013) Alessio Paffoni et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Paracrine activation of WNT/ -catenin pathway in uterine leiomyoma stem cells promotes tumor growth
- (2013) M. Ono et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- 1,25-Dihydroxyvitamin D3 Treatment Shrinks Uterine Leiomyoma Tumors in the Eker Rat Model1
- (2012) Sunil K. Halder et al. BIOLOGY OF REPRODUCTION
- Identification and characterization of the human leiomyoma side population as putative tumor-initiating cells
- (2012) Aymara Mas et al. FERTILITY AND STERILITY
- Antiproliferative and apoptotic effect of epigallocatechin-3-gallate on Ishikawa cells is accompanied by sex steroid receptor downregulation
- (2012) SEUNG BIN PARK et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Ulipristal Acetate versus Placebo for Fibroid Treatment before Surgery
- (2012) Jacques Donnez et al. NEW ENGLAND JOURNAL OF MEDICINE
- Ulipristal Acetate versus Leuprolide Acetate for Uterine Fibroids
- (2012) Jacques Donnez et al. NEW ENGLAND JOURNAL OF MEDICINE
- Role of Stem Cells in Human Uterine Leiomyoma Growth
- (2012) Masanori Ono et al. PLoS One
- Population Pharmacokinetics of Telapristone (CDB-4124) and its Active Monodemethylated Metabolite CDB-4453, with a Mixture Model for Total Clearance
- (2011) Denise Morris et al. AAPS Journal
- Growth factors and myometrium: biological effects in uterine fibroid and possible clinical implications
- (2011) Pasquapina Ciarmela et al. HUMAN REPRODUCTION UPDATE
- Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators
- (2011) Scott J. Lusher et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Reproductive toxicity of Rhizoma Sparganii (Sparganium stoloniferum Buch.-Ham.) in mice: Mechanisms of anti-angiogenesis and anti-estrogen pharmacologic activities
- (2011) Jie Sun et al. JOURNAL OF ETHNOPHARMACOLOGY
- The role of progesterone signaling in the pathogenesis of uterine leiomyoma
- (2011) J. Julie Kim et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Reconstruction of Endometrium from Human Endometrial Side Population Cell Lines
- (2011) Irene Cervelló et al. PLoS One
- CDB-4124, a Progesterone Receptor Modulator, Inhibits Mammary Carcinogenesis by Suppressing Cell Proliferation and Inducing Apoptosis
- (2010) R. Wiehle et al. Cancer Prevention Research
- Update on the role of leukemia inhibitory factor in assisted reproduction
- (2010) Lusine Aghajanova CURRENT OPINION IN OBSTETRICS & GYNECOLOGY
- Functional Differentiation of Uterine Stromal Cells Involves Cross-Regulation between Bone Morphogenetic Protein 2 and Krüppel-Like Factor (KLF) Family Members KLF9 and KLF13
- (2010) John Mark P. Pabona et al. ENDOCRINOLOGY
- Progesterone Is Essential for Maintenance and Growth of Uterine Leiomyoma
- (2010) Hiroshi Ishikawa et al. ENDOCRINOLOGY
- Leiomyoma Simultaneously Impair Endometrial BMP-2-Mediated Decidualization and Anticoagulant Expression through Secretion of TGF-β3
- (2010) Donna C. Sinclair et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Stem Cell-Like Properties of the Endometrial Side Population: Implication in Endometrial Regeneration
- (2010) Hirotaka Masuda et al. PLoS One
- Proinflammatory and Profibrotic Mediators: Principal Effectors of Leiomyoma Development as a Fibrotic Disorder
- (2010) Nasser Chegini SEMINARS IN REPRODUCTIVE MEDICINE
- Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells
- (2009) Dong Zhang et al. FERTILITY AND STERILITY
- Progestins Activate the AKT Pathway in Leiomyoma Cells and Promote Survival
- (2009) Anna V. Hoekstra et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression
- (2008) Minnie Malik et al. FERTILITY AND STERILITY
- Submucosal uterine leiomyomas have a global effect on molecular determinants of endometrial receptivity
- (2008) Beth W. Rackow et al. FERTILITY AND STERILITY
- Curcumin inhibits MPA-induced secretion of VEGF from T47-D human breast cancer cells
- (2008) Candace E. Carroll et al. MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
- Chemoprevention of fibroid tumors by [−]-epigallocatechin-3-gallate in quail
- (2008) Ibrahim H. Ozercan et al. NUTRITION RESEARCH
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