Integrated single-cell and bulk characterization of cuproptosis key regulator PDHB and association with tumor microenvironment infiltration in clear cell renal cell carcinoma

Cancer statistics, 2022

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Copper-induced tumor cell death mechanisms and antitumor theragnostic applications of copper complexes

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A proteogenomic analysis of clear cell renal cell carcinoma in a Chinese population

(2022) Yuanyuan Qu et al.   Nature Communications

A Novel Cuproptosis-Related Prognostic Gene Signature and Validation of Differential Expression in Clear Cell Renal Cell Carcinoma

(2022) Zilong Bian et al.   Genes

Cuproptosis and cuproptosis–related genes in rheumatoid arthritis: Implication, prospects, and perspectives

(2022) Jianan Zhao et al.   Frontiers in Immunology

Epigenome screening highlights that JMJD6 confers an epigenetic vulnerability and mediates sunitinib sensitivity in renal cell carcinoma

(2021) Chuanjie Zhang et al.   Clinical and Translational Medicine

Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

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TRIM37 orchestrates renal cell carcinoma progression via histone H2A ubiquitination-dependent manner

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Single-Cell RNA Sequencing in Multiple Pathologic Types of Renal Cell Carcinoma Revealed Novel Potential Tumor-Specific Markers

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Identification of biomarkers related to CD8+ T cell infiltration with gene co-expression network in clear cell renal cell carcinoma

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Poor Clinical Outcomes and Immunoevasive Contexture in Intratumoral IL-10-Producing Macrophages Enriched Gastric Cancer Patients

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Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

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CRISPR/Cas9 genome-wide loss-of-function screening identifies druggable cellular factors involved in sunitinib resistance in renal cell carcinoma

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Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage

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Mitochondrial metabolism promotes adaptation to proteotoxic stress

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Towards individualized therapy for metastatic renal cell carcinoma

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Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data

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(2019) W. Marston Linehan et al.   Nature Reviews Urology

Tumor Microenvironment Dynamics in Clear-Cell Renal Cell Carcinoma

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Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer

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Fast, sensitive and accurate integration of single-cell data with Harmony

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Adjuvant Sunitinib for High-risk Renal Cell Carcinoma After Nephrectomy: Subgroup Analyses and Updated Overall Survival Results

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Flavonoids-induced redox cycling of copper ions leads to generation of reactive oxygen species: A potential role in cancer chemoprevention

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Resistance to Systemic Therapies in Clear Cell Renal Cell Carcinoma: Mechanisms and Management Strategies

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma

(2018) David F. McDermott et al.   NATURE MEDICINE

Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma

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TRIM36, a novel androgen-responsive gene, enhances anti-androgen efficacy against prostate cancer by inhibiting MAPK/ERK signaling pathways

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The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer

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Targeted therapies for renal cell carcinoma

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Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

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Exosome-Transmitted lncARSR Promotes Sunitinib Resistance in Renal Cancer by Acting as a Competing Endogenous RNA

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A Description of the Clinical Proteomic Tumor Analysis Consortium (CPTAC) Common Data Analysis Pipeline

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Resistance to Targeted Therapies in Renal Cancer: The Importance of Changing the Mechanism of Action

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The pyruvate dehydrogenase complex in cancer: An old metabolic gatekeeper regulated by new pathways and pharmacological agents

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Preclinical Evidence That Trametinib Enhances the Response to Antiangiogenic Tyrosine Kinase Inhibitors in Renal Cell Carcinoma

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Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

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Regulatory T cells and TGF-β1 in clinically localized renal cell carcinoma: Comparison with age-matched healthy controls

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Integrative Genome-Wide Gene Expression Profiling of Clear Cell Renal Cell Carcinoma in Czech Republic and in the United States

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Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients

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Sunitinib Reverses Type-1 Immune Suppression and Decreases T-Regulatory Cells in Renal Cell Carcinoma Patients

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