Cuproptosis: Cellular and molecular mechanisms underlying copper-induced cell death

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes

(2021) Xinyu Zhu et al.   eLife

Copper biology

(2021) Tiffany Tsang et al.   CURRENT BIOLOGY

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice

(2020) Liam M. Guthrie et al.   SCIENCE

The histone H3-H4 tetramer is a copper reductase enzyme

(2020) Narsis Attar et al.   SCIENCE

Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli

(2020) Nancy Wiebelhaus et al.   ACS Chemical Biology

Mitochondrial metabolism promotes adaptation to proteotoxic stress

(2019) Peter Tsvetkov et al.   Nature Chemical Biology

Activation of autophagy, observed in liver tissues from patients with Wilson disease and from Atp7b-deficient animals, protects hepatocytes from copper-induced apoptosis

(2018) Elena V. Polishchuk et al.   GASTROENTEROLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL