Strategies for the Generation of Gene Modified Avian Models: Advancement in Avian Germline Transmission, Genome Editing, and Applications

Efficient production of recombinant human adiponectin in egg white using genome edited chickens

(2023) Young Min Kim et al.   Frontiers in Nutrition

Amplification of immunity by engineering chicken MDA5 combined with the C terminal domain (CTD) of RIG-I

(2022) Seung Je Woo et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Generation and characterization of genome-modified chondrocyte-like cells from the zebra finch cell line immortalized by c-MYC expression

(2022) Kyung Min Jung et al.   Frontiers in Zoology

Development and characterization of a CRISPR/Cas9-mediated RAG1 knockout chicken model lacking mature B and T cells

(2022) Kyung Youn Lee et al.   Frontiers in Immunology

Generation of genome-edited chicken and duck lines by adenovirus-mediated in vivo genome editing

(2022) Joonbum Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transplantation and enrichment of busulfan-resistant primordial germ cells into adult testes for efficient production of germline chimeras in songbirds

(2022) Kyung Min Jung et al.   BIOLOGY OF REPRODUCTION

Prime editing in chicken fibroblasts and primordial germ cells

(2022) Yuji Atsuta et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Comparative single‐cell transcriptomic analysis reveals differences in signaling pathways in gonadal primordial germ cells between chicken ( Gallus gallus ) and zebra finch ( Taeniopygia guttata )

(2022) Kyung Min Jung et al.   FASEB JOURNAL

Sequential verification of exogenous protein production in OVA gene-targeted chicken bioreactors

(2022) Young Min Kim et al.   POULTRY SCIENCE

In Vivo Inhibition of Marek’s Disease Virus in Transgenic Chickens Expressing Cas9 and gRNA against ICP4

(2021) Arjun Challagulla et al.   Microorganisms

Cas9-expressing chickens and pigs as resources for genome editing in livestock

(2021) Beate Rieblinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics

(2021) Jason Ioannidis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct allele introgression into pure chicken breeds using Sire Dam Surrogate (SDS) mating

(2021) Maeve Ballantyne et al.   Nature Communications

Asp149 and Asp152 in chicken and human ANP32A play an essential role in the interaction with influenza viral polymerase

(2021) Young Hyun Park et al.   FASEB JOURNAL

Primordial germ cells isolated from individual embryos of red junglefowl and indigenous pheasants of Thailand

(2021) Suparat Chaipipat et al.   THERIOGENOLOGY

In vivo enrichment of busulfan-resistant germ cells for efficient production of transgenic avian models

(2021) Young Min Kim et al.   Scientific Reports

Highly Efficient Genome Modification of Cultured Primordial Germ Cells with Lentiviral Vectors to Generate Transgenic Songbirds

(2021) Ivana Gessara et al.   Stem Cell Reports

DMRT1 gene disruption alone induces incomplete gonad feminization in chicken

(2021) Hong Jo Lee et al.   FASEB JOURNAL

Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells

(2021) Ruifeng Zhao et al.   Nature Communications

Single-Cell RNA Sequencing Revealed the Heterogeneity of Gonadal Primordial Germ Cells in Zebra Finch (Taeniopygia guttata)

(2021) Kyung Min Jung et al.   Frontiers in Cell and Developmental Biology

Generation of myostatin‐knockout chickens mediated by D10A‐Cas9 nickase

(2020) Gap‐Don Kim et al.   FASEB JOURNAL

Muscle Hyperplasia in Japanese Quail by Single Amino Acid Deletion in MSTN Propeptide

(2020) Joonbum Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Precise CRISPR/Cas9 editing of the NHE1 gene renders chickens resistant to the J subgroup of avian leukosis virus

(2020) Anna Koslová et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Moss-Derived Human Recombinant GAA Provides an Optimized Enzyme Uptake in Differentiated Human Muscle Cells of Pompe Disease

(2020) Stefan Hintze et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Production of quail (Coturnix japonica) germline chimeras by transfer of Ficoll-enriched spermatogonial stem cells

(2020) Jae Yong Han et al.   THERIOGENOLOGY

Principles of Genetic Engineering

(2020) Thomas M. Lanigan et al.   Genes

Germline engineering of the chicken genome using CRISPR/Cas9 by in vivo transfection of PGCs

(2020) Arjun Challagulla et al.   ANIMAL BIOTECHNOLOGY

Primordial germ cell‐specific expression of eGFP in transgenic chickens

(2020) Yota Hagihara et al.   GENESIS

Abrogation of Marek’s disease virus replication using CRISPR/Cas9

(2020) Ibrahim T. Hagag et al.   Scientific Reports

Highly elevated base excision repair pathway in primordial germ cells causes low base editing activity in chickens

(2020) Kyung Youn Lee et al.   FASEB JOURNAL

Applications of CRISPR–Cas in agriculture and plant biotechnology

(2020) Haocheng Zhu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture

(2019) Kunling Chen et al.   Annual Review of Plant Biology

Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J

(2019) Hong Jo Lee et al.   Journal of Animal Science and Biotechnology

Direct delivery of adenoviral CRISPR/Cas9 vector into the blastoderm for generation of targeted gene knockout in quail

(2019) Joonbum Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potential benefits of gene editing for the future of poultry farming

(2019) Mark L. Tizard et al.   TRANSGENIC RESEARCH

Species specific differences in use of ANP32 proteins by influenza A virus

(2019) Jason S Long et al.   eLife

Gene Therapy Tools for Brain Diseases

(2019) Selene Ingusci et al.   Frontiers in Pharmacology

Host-Specific Restriction of Avian Influenza Virus Caused by Differential Dynamics of ANP32 Family Members

(2019) Young Hyun Park et al.   JOURNAL OF INFECTIOUS DISEASES

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

Identification and characterization of primordial germ cells in a vocal learning Neoaves species, the zebra finch

(2019) Kyung Min Jung et al.   FASEB JOURNAL

The transgenic chicken derived anti-CD20 monoclonal antibodies exhibits greater anti-cancer therapeutic potential with enhanced Fc effector functions

(2018) Young Min Kim et al.   BIOMATERIALS

The early development of germ cells in chicken

(2018) Young Min Kim et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

In vitro improvement of quail primordial germ cell expansion through activation of TGF-beta signaling pathway

(2018) Saeed Yakhkeshi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

CRISPR/Cas9 Genome Editing: A Promising Tool for Therapeutic Applications of Induced Pluripotent Stem Cells

(2018) Yanli Zhang et al.   Current Stem Cell Research & Therapy

Primordial germ cell-mediated transgenesis and genome editing in birds

(2018) Jae Yong Han et al.   Journal of Animal Science and Biotechnology

CRISPR/Cas9 and Genome Editing for Viral Disease—Is Resistance Futile?

(2018) Harshana S. De Silva Feelixge et al.   ACS Infectious Diseases

Generation of Porcine-Induced Pluripotent Stem Cells by Using OCT4 and KLF4 Porcine Factors

(2018) Kai Liu et al.   Cellular Reprogramming

Disruption of G0/G1 switch gene 2 (G0S2) reduced abdominal fat deposition and altered fatty acid composition in chicken

(2018) Tae Sub Park et al.   FASEB JOURNAL

Efficient production of human interferon beta in the white of eggs from ovalbumin gene–targeted hens

(2018) Isao Oishi et al.   Scientific Reports

A chicken bioreactor for efficient production of functional cytokines

(2018) Lissa R. Herron et al.   BMC BIOTECHNOLOGY

Avian Bioreactor Systems: A Review

(2018) Rachel M. Woodfint et al.   MOLECULAR BIOTECHNOLOGY

In vitro culture and characterization of duck primordial germ cells

(2018) Yi-Chen Chen et al.   POULTRY SCIENCE

Creating Disease Resistant Chickens: A Viable Solution to Avian Influenza?

(2018) Fong Looi et al.   Viruses-Basel

Genetic Resistance to Avian Leukosis Viruses Induced by CRISPR/Cas9 Editing of Specific Receptor Genes in Chicken Cells

(2018) Anna Koslová et al.   Viruses-Basel

Production of recombinant human acid α-glucosidase with high-mannose glycans in gnt1 rice for the treatment of Pompe disease

(2017) Jae-Wan Jung et al.   JOURNAL OF BIOTECHNOLOGY

Size-dependent isolation of primordial germ cells from avian species

(2017) Kyung M. Jung et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Isolation, Characterization, and In Vitro Culturing of Spermatogonial Stem Cells in Japanese Quail (Coturnix japonica)

(2017) Ravindran Kumar Pramod et al.   STEM CELLS AND DEVELOPMENT

Global poultry production: current state and future outlook and challenges

(2017) A. MOTTET et al.   WORLDS POULTRY SCIENCE JOURNAL

Male fertility restored by transplanting primordial germ cells into testes: a new way towards efficient transgenesis in chicken

(2017) Pavel Trefil et al.   Scientific Reports

Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring

(2016) Chao-Hui Li et al.   CELL RESEARCH

Site-specific recombination in the chicken genome using Flipase recombinase–mediated cassette exchange

(2016) Hong Jo Lee et al.   FASEB JOURNAL

Poultry genetic resource conservation using primordial germ cells

(2016) Yoshiaki NAKAMURA   JOURNAL OF REPRODUCTION AND DEVELOPMENT

Species difference in ANP32A underlies influenza A virus polymerase host restriction

(2016) Jason S. Long et al.   NATURE

FDA approves 'farmaceutical' drug from transgenic chickens

(2016) Cormac Sheridan   NATURE BIOTECHNOLOGY

DAZLExpression Explains Origin and Central Formation of Primordial Germ Cells in Chickens

(2016) Hyung Chul Lee et al.   STEM CELLS AND DEVELOPMENT

Wnt/β-catenin signaling pathway activation is required for proliferation of chicken primordial germ cells in vitro

(2016) Hyung Chul Lee et al.   Scientific Reports

Germline Gene Editing in Chickens by Efficient CRISPR-Mediated Homologous Recombination in Primordial Germ Cells

(2016) Lazar Dimitrov et al.   PLoS One

Targeted mutagenesis in chicken using CRISPR/Cas9 system

(2016) Isao Oishi et al.   Scientific Reports

Zebrafish germ cells: motility and guided migration

(2015) Azadeh Paksa et al.   CURRENT OPINION IN CELL BIOLOGY

Deposition of bioactive human epidermal growth factor in the egg white of transgenic hens using an oviduct-specific minisynthetic promoter

(2015) Tae Sub Park et al.   FASEB JOURNAL

Human mutant huntingtin disrupts vocal learning in transgenic songbirds

(2015) Wan-chun Liu et al.   NATURE NEUROSCIENCE

Transgenic songbirds with suppressed or enhanced activity of CREB transcription factor

(2015) Kentaro Abe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FGF, Insulin, and SMAD Signaling Cooperate for Avian Primordial Germ Cell Self-Renewal

(2015) Jemima Whyte et al.   Stem Cell Reports

Expression of Recombinant Human Lysozyme in Egg Whites of Transgenic Hens

(2015) Dainan Cao et al.   PLoS One

Germline-competent stem cell in avian species and its application

(2014) JaeYong Han et al.   ASIAN JOURNAL OF ANDROLOGY

A guide to genome engineering with programmable nucleases

(2014) Hyongbum Kim et al.   NATURE REVIEWS GENETICS

The potential for archiving and reconstituting valuable strains of turkey (Meleagris gallopavo) using primordial germ cells

(2014) Alexander J. Wade et al.   POULTRY SCIENCE

Targeted gene knockout in chickens mediated by TALENs

(2014) T. S. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development, differentiation and manipulation of chicken germ cells

(2013) Yoshiaki Nakamura et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Long-term, inducible gene loss-of-function in the chicken embryo

(2013) Olivier Serralbo et al.   GENESIS

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

(2013) Y. H. Sung et al.   GENOME RESEARCH

Applications of Avian Transgenesis

(2013) B. B. Scott et al.   ILAR JOURNAL

Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease

(2013) Seung Woo Cho et al.   NATURE BIOTECHNOLOGY

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Demonstration of CRISPR/Cas9/sgRNA-mediated targeted gene modification in Arabidopsis, tobacco, sorghum and rice

(2013) Wenzhi Jiang et al.   NUCLEIC ACIDS RESEARCH

Cleavage Events and Sperm Dynamics in Chick Intrauterine Embryos

(2013) Hyung Chul Lee et al.   PLoS One

Immunoglobulin knockout chickens via efficient homologous recombination in primordial germ cells

(2013) B. Schusser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

Mammalian genes induce partially reprogrammed pluripotent stem cells in non-mammalian vertebrate and invertebrate species

(2013) Ricardo Antonio Rosselló et al.   eLife

Interspecific Germline Transmission of Cultured Primordial Germ Cells

(2012) Marie-Cecile van de Lavoir et al.   PLoS One

piggyBac transposition into primordial germ cells is an efficient tool for transgenesis in chickens

(2012) T. S. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient genetic modification and germ-line transmission of primordial germ cells using piggyBac and Tol2 transposons

(2012) J. Macdonald et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Effects of different feeder layers on short-term culture of prepubertal bovine testicular germ cells In-vitro

(2012) Z. Nasiri et al.   THERIOGENOLOGY

Homologous Recombination in Rat Germline Stem Cells1

(2011) Mito Kanatsu-Shinohara et al.   BIOLOGY OF REPRODUCTION

Production of Chicken Progeny (Gallus gallus domesticus) from Interspecies Germline Chimeric Duck (Anas domesticus) by Primordial Germ Cell Transfer1

(2011) Chunhai Liu et al.   BIOLOGY OF REPRODUCTION

Avian-Induced Pluripotent Stem Cells Derived Using Human Reprogramming Factors

(2011) Yangqing Lu et al.   STEM CELLS AND DEVELOPMENT

Germline Replacement by Transfer of Primordial Germ Cells into Partially Sterilized Embryos in the Chicken1

(2010) Yoshiaki Nakamura et al.   BIOLOGY OF REPRODUCTION

Generating knockout rats by transposon mutagenesis in spermatogonial stem cells

(2010) Zsuzsanna Izsvák et al.   NATURE METHODS

Basic Fibroblast Growth Factor Activates MEK/ERK Cell Signaling Pathway and Stimulates the Proliferation of Chicken Primordial Germ Cells

(2010) Jin Won Choi et al.   PLoS One

Primordial Germ Cell-Mediated Chimera Technology Produces Viable Pure-Line Houbara Bustard Offspring: Potential for Repopulating an Endangered Species

(2010) Ulrich Wernery et al.   PLoS One

Characterisation and Germline Transmission of Cultured Avian Primordial Germ Cells

(2010) Joni Macdonald et al.   PLoS One

Association of RIG-I with innate immunity of ducks to influenza

(2010) M. R. W. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Generation of Nonhuman Primate Induced Pluripotent Stem Cells

(2010) Bonan Zhong et al.   STEM CELLS AND DEVELOPMENT

Ectopic expression of Cvh (Chicken Vasa homologue) mediates the reprogramming of chicken embryonic stem cells to a germ cell fate

(2009) Fabrice Lavial et al.   DEVELOPMENTAL BIOLOGY

Transposon-mediated genome manipulation in vertebrates

(2009) Zoltán Ivics et al.   NATURE METHODS

Mechanisms guiding primordial germ cell migration: strategies from different organisms

(2009) Brian E. Richardson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transgenic songbirds offer an opportunity to develop a genetic model for vocal learning

(2009) R. J. Agate et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effects of growth factors on in vitro-cultured porcine testicular cells

(2009) Ewart W Kuijk et al.   REPRODUCTION

Production of Transgenic Rats via Lentiviral Transduction and Xenogeneic Transplantation of Spermatogonial Stem Cells1

(2008) Mito Kanatsu-Shinohara et al.   BIOLOGY OF REPRODUCTION

Reproduction of Wild Birds via Interspecies Germ Cell Transplantation1

(2008) Seok Jin Kang et al.   BIOLOGY OF REPRODUCTION

Germ cells and transgenesis in chickens

(2008) Jae Yong Han   COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES

Generation of transgenic quail through germ cell-mediated germline transmission

(2008) Sang Su Shin et al.   FASEB JOURNAL

Isolation and Characterization of Pluripotent Human Spermatogonial Stem Cell-Derived Cells

(2008) Nina Kossack et al.   STEM CELLS