DMRT1 gene disruption alone induces incomplete gonad feminization in chicken

Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics

(2021) Jason Ioannidis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oestrogen in the chick embryo can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex that can support oogenesis

(2020) Silvana Guioli et al.   DEVELOPMENT

Insights into Gonadal Sex Differentiation Provided by Single-Cell Transcriptomics in the Chicken Embryo

(2020) Martin Andres Estermann et al.   Cell Reports

Prediction-based highly sensitive CRISPR off-target validation using target-specific DNA enrichment

(2020) Seung-Hun Kang et al.   Nature Communications

GOTI, a method to identify genome-wide off-target effects of genome editing in mouse embryos

(2020) Erwei Zuo et al.   Nature Protocols

Targeted gene insertion into Z chromosome of chicken primordial germ cells for avian sexing model development

(2019) Hong Jo Lee et al.   FASEB JOURNAL

Xist RNA in action: Past, present, and future

(2019) Agnese Loda et al.   PLoS Genetics

Regulation of gene expression by cis-acting long non-coding RNAs

(2019) Noa Gil et al.   NATURE REVIEWS GENETICS

Coherent apoptotic and autophagic activities involved in regression of chicken postovulatory follicles

(2018) Xin Lin et al.   Aging-US

Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements

(2018) Michael Kosicki et al.   NATURE BIOTECHNOLOGY

RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation

(2018) Maria Kim et al.   PLoS Genetics

Distinct and Cooperative Roles ofamhanddmrt1in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish

(2017) Qiaohong Lin et al.   GENETICS

Technical note: Induction of pluripotent stem cell-like cells from chicken feather follicle cells1

(2017) Y. M. Kim et al.   JOURNAL OF ANIMAL SCIENCE

Distinct and Cooperative Roles ofamhanddmrt1in Self-Renewal and Differentiation of Male Germ Cells in Zebrafish

(2017) Qiaohong Lin et al.   GENETICS

The genetic make-up of ovarian development and function: the focus on the transcription factor FOXL2

(2016) M. Elzaiat et al.   CLINICAL GENETICS

Site-specific recombination in the chicken genome using Flipase recombinase–mediated cassette exchange

(2016) Hong Jo Lee et al.   FASEB JOURNAL

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

DAZLExpression Explains Origin and Central Formation of Primordial Germ Cells in Chickens

(2016) Hyung Chul Lee et al.   STEM CELLS AND DEVELOPMENT

DMRT1 is required for Müllerian duct formation in the chicken embryo

(2015) K.L. Ayers et al.   DEVELOPMENTAL BIOLOGY

Bioinformatics Annotation of Human Y Chromosome-Encoded Protein Pathways and Interactions

(2015) Deivendran Rengaraj et al.   JOURNAL OF PROTEOME RESEARCH

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

An ancient protein-DNA interaction underlying metazoan sex determination

(2015) Mark W Murphy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

(2014) S. Bae et al.   BIOINFORMATICS

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads

(2014) Luke S. Lambeth et al.   DEVELOPMENTAL BIOLOGY

Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system

(2014) Tetsushi Sakuma et al.   Scientific Reports

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Molecular antagonism between X-chromosome and autosome signals determines nematode sex

(2013) B. Farboud et al.   GENES & DEVELOPMENT

Regulation of pluripotency in male germline stem cells by Dmrt1

(2013) S. Takashima et al.   GENES & DEVELOPMENT

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

The long non-coding RNA, MHM, plays a role in chicken embryonic development, including gonadogenesis

(2012) Kelly N. Roeszler et al.   DEVELOPMENTAL BIOLOGY

Analysis of meiosis regulators in human gonads: a sexually dimorphic spatio-temporal expression pattern suggests involvement of DMRT1 in meiotic entry

(2012) A. Jorgensen et al.   MOLECULAR HUMAN REPRODUCTION

Dosage compensation in Drosophila melanogaster: epigenetic fine-tuning of chromosome-wide transcription

(2012) Thomas Conrad et al.   NATURE REVIEWS GENETICS

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary

(2011) Anthony D. Krentz et al.   DEVELOPMENTAL BIOLOGY

DMRT1 prevents female reprogramming in the postnatal mammalian testis

(2011) Clinton K. Matson et al.   NATURE

The maturation of photoreceptors in the avian retina is stimulated by thyroid hormone

(2011) A.J. Fischer et al.   NEUROSCIENCE

Opposite roles of DMRT1 and its W-linked paralogue, DM-W, in sexual dimorphism of Xenopus laevis: implications of a ZZ/ZW-type sex-determining system

(2010) S. Yoshimoto et al.   DEVELOPMENT

The Mammalian Doublesex Homolog DMRT1 Is a Transcriptional Gatekeeper that Controls the Mitosis versus Meiosis Decision in Male Germ Cells

(2010) Clinton K. Matson et al.   DEVELOPMENTAL CELL

Somatic sex identity is cell autonomous in the chicken

(2010) D. Zhao et al.   NATURE

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

(2010) M. W. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dosage compensation and the global re-balancing of aneuploid genomes

(2010) Matthias Prestel et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The avian Z-linked gene DMRT1 is required for male sex determination in the chicken

(2009) Craig A. Smith et al.   NATURE

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS