Expression of L1 retrotransposons in granulocytes from patients with active systemic lupus erythematosus

Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression

(2022) William Garland et al.   MOLECULAR CELL

RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs

(2021) Erica M. Briggs et al.   Mobile DNA

Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus

(2021) Kennedy C. Ukadike et al.   Journal of Clinical Medicine

Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation

(2020) Huipeng Jiao et al.   NATURE

L1 drives IFN in senescent cells and promotes age-associated inflammation

(2019) Marco De Cecco et al.   NATURE

SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina

(2019) Berta N Vazquez et al.   NUCLEIC ACIDS RESEARCH

High prevalence and disease correlation of autoantibodies against p40 encoded by long interspersed nuclear elements ( LINE ‐1) in systemic lupus erythematosus

(2019) Victoria Carter et al.   Arthritis & Rheumatology

Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function

(2019) Emily M. Adney et al.   GENETICS

The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes

(2018) Luisa Robbez-Masson et al.   GENOME RESEARCH

Defective regulation of L1 endogenous retroelements in primary Sjogren's syndrome and systemic lupus erythematosus: Role of methylating enzymes

(2018) Clio P. Mavragani et al.   JOURNAL OF AUTOIMMUNITY

ZBP1: Innate Sensor Regulating Cell Death and Inflammation

(2018) Teneema Kuriakose et al.   TRENDS IN IMMUNOLOGY

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p

(2018) Elena Khazina et al.   eLife

Dissection of affinity captured LINE-1 macromolecular complexes

(2018) Martin S Taylor et al.   eLife

ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response

(2018) Huan Lian et al.   Nature Communications

Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome

(2018) Gillian I. Rice et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aicardi–Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion

(2017) Peng Li et al.   NUCLEIC ACIDS RESEARCH

Decreased mRNA expression levels of DNA methyltransferases type 1 and 3A in systemic lupus erythematosus

(2017) Mariusz J. Nawrocki et al.   RHEUMATOLOGY INTERNATIONAL

Expression of Long Interspersed Nuclear Element 1 Retroelements and Induction of Type I Interferon in Patients With Systemic Autoimmune Disease

(2016) Clio P. Mavragani et al.   Arthritis & Rheumatology

TEtranscripts: a package for including transposable elements in differential expression analysis of RNA-seq datasets

(2015) Ying Jin et al.   BIOINFORMATICS

Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases

(2015) Daxing Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression

(2015) T. Hung et al.   SCIENCE

SAMHD1 Inhibits LINE-1 Retrotransposition by Promoting Stress Granule Formation

(2015) Siqi Hu et al.   PLoS Genetics

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi–Goutières syndrome

(2015) Yoong Wearn Lim et al.   eLife

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age

(2014) Michael Van Meter et al.   Nature Communications

LINE-1 retrotransposons and let-7 miRNA: partners in the pathogenesis of cancer?

(2014) Stephen Ohms et al.   Frontiers in Genetics

Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition

(2013) Martin S. Taylor et al.   CELL

Ultraviolet B enhances DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus via inhibiting DNMT1 catalytic activity

(2013) Zhouwei Wu et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

(2013) John L. Goodier et al.   NUCLEIC ACIDS RESEARCH

Common and Specific Associations of Anti-SSA/Ro60 and Anti-Ro52/TRIM21 Antibodies in Systemic Lupus Erythematosus

(2013) Aurora Menéndez et al.   TheScientificWorldJOURNAL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition

(2011) Lixin Dai et al.   BMC BIOCHEMISTRY

Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

(2011) Michal Lubas et al.   MOLECULAR CELL

Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition

(2011) Elena Khazina et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polymerization and nucleic acid-binding properties of human L1 ORF1 protein

(2011) Kathryn E. Callahan et al.   NUCLEIC ACIDS RESEARCH

Nucleic acid chaperone properties of ORF1p from the non-LTR retrotransposon, LINE-1

(2011) Sandra L. Martin   RNA Biology

Cytosolic DNA sensors regulating type I interferon induction

(2011) Sinead E. Keating et al.   TRENDS IN IMMUNOLOGY

Discrete subcellular partitioning of human retrotransposon RNAs despite a common mechanism of genome insertion

(2010) J. L. Goodier et al.   HUMAN MOLECULAR GENETICS

Characterization of LINE-1 Ribonucleoprotein Particles

(2010) Aurélien J. Doucet et al.   PLoS Genetics

Nucleoside Analogue Reverse Transcriptase Inhibitors Differentially Inhibit Human LINE-1 Retrotransposition

(2008) R. Brad Jones et al.   PLoS One