The activity of the aryl hydrocarbon receptor in T cells tunes the gut microenvironment to sustain autoimmunity and neuroinflammation

Intestinal commensal microbiota and cytokines regulate Fut2+ Paneth cells for gut defense

(2022) Mariko Kamioka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The aryl hydrocarbon receptor and the gut–brain axis

(2021) Andreia Barroso et al.   Cellular & Molecular Immunology

Gut Microbiome in Progressive Multiple Sclerosis

(2021) Laura M. Cox et al.   ANNALS OF NEUROLOGY

POMAShiny: A user-friendly web-based workflow for metabolomics and proteomics data analysis

(2021) Pol Castellano-Escuder et al.   PLoS Computational Biology

The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota

(2021) Osama A. Abdulla et al.   Frontiers in Immunology

Aryl Hydrocarbon Receptor (AhR) Activation by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD) Dose-Dependently Shifts the Gut Microbiome Consistent with the Progression of Non-Alcoholic Fatty Liver Disease

(2021) Russell R. Fling et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The microbiome and inflammatory bowel disease

(2020) Kerri L. Glassner et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differentiation of Pathogenic Th17 Cells Is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis

(2020) Constance C. Angelou et al.   Frontiers in Immunology

The microbiome and rheumatoid arthritis

(2020) Anne-Sophie Bergot et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation

(2020) Pavan Bhargava et al.   JOURNAL OF CLINICAL INVESTIGATION

Selective AhR knockout in langerin-expressing cells abates Langerhans cells and polarizes Th2/Tr1 in epicutaneous protein sensitization

(2020) Chien-Hui Hong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental autoimmune encephalomyelitis is associated with changes of the microbiota composition in the gastrointestinal tract

(2020) David M. Johanson et al.   Scientific Reports

Myelin as a regulator of development of the microbiota-gut-brain axis

(2020) Ciara E. Keogh et al.   BRAIN BEHAVIOR AND IMMUNITY

Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles

(2020) Fang Yang et al.   Microbial Cell Factories

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Gut microbes and metabolites as modulators of blood-brain barrier integrity and brain health

(2019) Aimée Parker et al.   Gut Microbes

Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis

(2019) Donovan Duc et al.   Cell Reports

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

The Gut Microbiome and Multiple Sclerosis

(2018) Javier Ochoa-Repáraz et al.   Cold Spring Harbor Perspectives in Medicine

Cytokine Regulation in Human CD4 T Cells by the Aryl Hydrocarbon Receptor and Gq-Coupled Receptors

(2018) Jeremy P. McAleer et al.   Scientific Reports

Bile Acid Synthesis: From Nature to the Chemical Modification and Synthesis and Their Applications as Drugs and Nutrients

(2018) Tanja M. Šarenac et al.   Frontiers in Pharmacology

Regulation of autoimmune myocarditis by host responses to the microbiome

(2017) Jobert G. Barin et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Lineage-Specific Metabolic Properties and Vulnerabilities of T Cells in the Demyelinating Central Nervous System

(2017) Scott M. Seki et al.   JOURNAL OF IMMUNOLOGY

The regulation of gut mucosal IgA B-cell responses: recent developments

(2017) N Y Lycke et al.   Mucosal Immunology

Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice

(2017) Kerstin Berer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation

(2017) Allison K Ehrlich et al.   TOXICOLOGICAL SCIENCES

The aryl hydrocarbon receptor controls cell-fate decisions in B cells

(2016) Bharat Vaidyanathan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Obeticholic acid, a synthetic bile acid agonist of the farnesoid X receptor, attenuates experimental autoimmune encephalomyelitis

(2016) Peggy P. Ho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor

(2016) Joel Kaye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

LRP1 expression in microglia is protective during CNS autoimmunity

(2016) Tzu-Ying Chuang et al.   Acta Neuropathologica Communications

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism

(2016) Agata Korecka et al.   npj Biofilms and Microbiomes

The microbiome in asthma

(2015) Yvonne J. Huang et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

T cell mediated pathogenesis in EAE: Molecular mechanisms

(2015) FlorianC Kurschus   Biomedical Journal

Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

(2015) Sachiko Miyake et al.   PLoS One

Activation of the aryl hydrocarbon receptor affects activation and function of human monocyte-derived dendritic cells

(2014) C. Wang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

A GPBAR1 (TGR5) Small Molecule Agonist Shows Specific Inhibitory Effects on Myeloid Cell Activation In Vitro and Reduces Experimental Autoimmune Encephalitis (EAE) In Vivo

(2014) Nuruddeen D. Lewis et al.   PLoS One

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

(2013) Sama I. Sayin et al.   Cell Metabolism

phyloseq: An R Package for Reproducible Interactive Analysis and Graphics of Microbiome Census Data

(2013) Paul J. McMurdie et al.   PLoS One

Differential Influences of the Aryl Hydrocarbon Receptor on Th17 Mediated Responses in vitro and in vivo

(2013) João H. Duarte et al.   PLoS One

Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells

(2012) Mary A. Zimmerman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

MetaMapp: mapping and visualizing metabolomic data by integrating information from biochemical pathways and chemical and mass spectral similarity

(2012) Dinesh K Barupal et al.   BMC BIOINFORMATICS

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

(2010) F. J. Quintana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human gut microbiome adopts an alternative state following small bowel transplantation

(2009) A. L. Hartman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET