Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH

Tryptophan mutations in G3BP1 tune the stability of a cellular signaling hub by weakening transient interactions with Caprin1 and USP10

(2022) Colin T. Sheehan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yin and yang regulation of stress granules by Caprin-1

(2022) Dan Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De novo variants in genes regulating stress granule assembly associate with neurodevelopmental disorders

(2022) Xiangbin Jia et al.   Science Advances

High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate

(2021) Brian D. Freibaum et al.   JOURNAL OF CELL BIOLOGY

Biomolecular condensates at the nexus of cellular stress, protein aggregation disease and ageing

(2021) Simon Alberti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stress granule formation, disassembly, and composition are regulated by alphavirus ADP-ribosylhydrolase activity

(2021) Aravinth Kumar Jayabalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ligand effects on phase separation of multivalent macromolecules

(2021) Kiersten M. Ruff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FoldAffinity: binding affinities from nDSF experiments

(2021) Stephan Niebling et al.   Scientific Reports

Generic nature of the condensed states of proteins

(2021) Monika Fuxreiter et al.   NATURE CELL BIOLOGY

Higher-order organization of biomolecular condensates

(2021) Charlotte M. Fare et al.   Open Biology

eSPC: an online data-analysis platform for molecular biophysics

(2021) Osvaldo Burastero et al.   Acta Crystallographica Section D-Structural Biology

Distinct features of stress granule proteins predict localization in membraneless organelle

(2020) Erich R. Kuechler et al.   JOURNAL OF MOLECULAR BIOLOGY

Competing Protein-RNA Interaction Networks Control Multiphase Intracellular Organization

(2020) David W. Sanders et al.   CELL

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

(2020) Jordina Guillén-Boixet et al.   CELL

Composition-dependent thermodynamics of intracellular phase separation

(2020) Joshua A. Riback et al.   NATURE

Liquid-liquid phase separation drives skin barrier formation

(2020) Felipe Garcia Quiroz et al.   SCIENCE

Stress granule subtypes: an emerging link to neurodegeneration

(2020) Vivek M. Advani et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular mechanisms of stress granule assembly and disassembly

(2020) Sarah Hofmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Single-Molecule Imaging Reveals Translation of mRNAs Localized to Stress Granules

(2020) Daniel Mateju et al.   CELL

The multi‐functional RNA‐binding protein G3BP1 and its potential implication in neurodegenerative disease

(2020) Hadjara Sidibé et al.   JOURNAL OF NEUROCHEMISTRY

Stress granule: a promising target for cancer treatment

(2019) Xiaomeng Gao et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phosphorylation of G3BP1-S149 does not influence stress granule assembly

(2019) Marc D. Panas et al.   JOURNAL OF CELL BIOLOGY

Separate domains of G3BP promote efficient clustering of alphavirus replication complexes and recruitment of the translation initiation machinery

(2019) Benjamin Götte et al.   PLoS Pathogens

Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation

(2019) Tae Hun Kim et al.   SCIENCE

Properties of Stress Granule and P-Body Proteomes

(2019) Ji-Young Youn et al.   MOLECULAR CELL

Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules

(2018) Sebastian Markmiller et al.   CELL

The Enigmatic Alphavirus Non-Structural Protein 3 (nsP3) Revealing Its Secrets at Last

(2018) Benjamin Götte et al.   Viruses-Basel

CellProfiler 3.0: Next-generation image processing for biology

(2018) Claire McQuin et al.   PLOS BIOLOGY

The roles and mechanisms of G3BP1 in tumour promotion

(2018) Cong-Hui Zhang et al.   JOURNAL OF DRUG TARGETING

Multiple Modes of Protein–Protein Interactions Promote RNP Granule Assembly

(2018) Tanja Mittag et al.   JOURNAL OF MOLECULAR BIOLOGY

Affinity and specificity of motif-based protein–protein interactions

(2018) Ylva Ivarsson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Local pH and effective pKA of weak polyelectrolytes – insights from computer simulations

(2017) Lucie Nová et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Mechanistic insights into mammalian stress granule dynamics

(2016) Marc D. Panas et al.   JOURNAL OF CELL BIOLOGY

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Integration and global analysis of isothermal titration calorimetry data for studying macromolecular interactions

(2016) Chad A Brautigam et al.   Nature Protocols

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication

(2016) Tim Schulte et al.   Open Biology

A pH-driven transition of the cytoplasm from a fluid- to a solid-like state promotes entry into dormancy

(2016) Matthias Christoph Munder et al.   eLife

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

Crystal structure of a dimerization domain of human Caprin-1: insights into the assembly of an evolutionarily conserved ribonucleoprotein complex consisting of Caprin-1, FMRP and G3BP1

(2016) Yuhong Wu et al.   Acta Crystallographica Section D-Structural Biology

Crystal structure of the G3BP2 NTF2-like domain in complex with a canonical FGDF motif peptide

(2015) Ole Kristensen   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase

(2015) Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-precision, automated integration of multiple isothermal titration calorimetric thermograms: New features of NITPIC

(2015) Thomas H. Scheuermann et al.   METHODS

Atomic view of the histidine environment stabilizing higher-pH conformations of pH-dependent proteins

(2015) Céline Valéry et al.   Nature Communications

Viral and Cellular Proteins Containing FGDF Motifs Bind G3BP to Block Stress Granule Formation

(2015) Marc D. Panas et al.   PLoS Pathogens

Dose-Response Analysis Using R

(2015) Christian Ritz et al.   PLoS One

A Million Peptide Motifs for the Molecular Biologist

(2014) Peter Tompa et al.   MOLECULAR CELL

Considering Protonation as a Posttranslational Modification Regulating Protein Structure and Function

(2013) André Schönichen et al.   Annual Review of Biophysics

IMAAAGINE: a webserver for searching hypothetical 3D amino acid side chain arrangements in the Protein Data Bank

(2013) Nurul Nadzirin et al.   NUCLEIC ACIDS RESEARCH

Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)

(2013) Sergey Lyskov et al.   PLoS One

Stress granules and cell signaling: more than just a passing phase?

(2013) Nancy Kedersha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rapid Calculation of Protein pKa Values Using Rosetta

(2012) Krishna Praneeth Kilambi et al.   BIOPHYSICAL JOURNAL

XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS

(2012) Michael Krug et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Sequestration of G3BP coupled with efficient translation inhibits stress granules in Semliki Forest virus infection

(2012) Marc D. Panas et al.   MOLECULAR BIOLOGY OF THE CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Fragile Mental Retardation Protein Interacts with the RNA-Binding Protein Caprin1 in Neuronal RiboNucleoProtein Complexes

(2012) Rachid El Fatimy et al.   PLoS One

Macromolecular complexes in crystals and solutions

(2011) Evgeny Krissinel   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Poly(ADP-Ribose) Regulates Stress Responses and MicroRNA Activity in the Cytoplasm

(2011) Anthony K.L. Leung et al.   MOLECULAR CELL

Predicting the Tolerated Sequences for Proteins and Protein Interfaces Using RosettaBackrub Flexible Backbone Design

(2011) Colin A. Smith et al.   PLoS One

USP10 Regulates p53 Localization and Stability by Deubiquitinating p53

(2010) Jian Yuan et al.   CELL

Stress granules

(2009) Paul Anderson et al.   CURRENT BIOLOGY

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Modulation of protein properties in living cells using nanobodies

(2009) Axel Kirchhofer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL