A peripheral signature of Alzheimer’s disease featuring microbiota-gut-brain axis markers

ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy

(2023) Dong-oh Seo et al.   SCIENCE

Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation

(2022) Chun Chen et al.   GUT

Combination of gut microbiota and plasma amyloid-β as a potential index for identifying preclinical Alzheimer’s disease: a cross-sectional analysis from the SILCODE study

(2022) Can Sheng et al.   Alzheimers Research & Therapy

Crosstalk Between the Gut Microbiota and Epithelial Cells Under Physiological and Infectious Conditions

(2022) An Zhou et al.   Frontiers in Cellular and Infection Microbiology

Gut Microbiota Composition Is Related to AD Pathology

(2022) Barbara J. H. Verhaar et al.   Frontiers in Immunology

Relationship Between the Gut Microbiota and Alzheimer’s Disease: A Systematic Review

(2022) Elisa Marina González Cordero et al.   JOURNAL OF ALZHEIMERS DISEASE

Influence of the Microbiota-Gut-Brain Axis on Cognition in Alzheimer’s Disease

(2022) Yael-Natalie H. Escobar et al.   JOURNAL OF ALZHEIMERS DISEASE

Signature of Alzheimer’s Disease in Intestinal Microbiome: Results From the AlzBiom Study

(2022) Christoph Laske et al.   Frontiers in Neuroscience

Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer’s Disease or Mild Cognitive Impairment

(2021) Mingyan Guo et al.   JOURNAL OF ALZHEIMERS DISEASE

The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy

(2021) Nicolas Ricard et al.   Nature Reviews Cardiology

Structural and Functional Dysbiosis of Fecal Microbiota in Chinese Patients With Alzheimer's Disease

(2021) Zongxin Ling et al.   Frontiers in Cell and Developmental Biology

Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition

(2021) Alessio Vittorio Colombo et al.   eLife

Endothelium as a Source and Target of H2S to Improve Its Trophism and Function

(2021) Valerio Ciccone et al.   Antioxidants

Microbiota-derived acetate enables the metabolic fitness of the brain innate immune system during health and disease

(2021) Daniel Erny et al.   Cell Metabolism

Neuronal Mitochondria Modulation of LPS-Induced Neuroinflammation

(2020) Micah Harland et al.   JOURNAL OF NEUROSCIENCE

The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication

(2020) Ygor Parladore Silva et al.   Frontiers in Endocrinology

Comparison of Bioinformatics Pipelines and Operating Systems for the Analyses of 16S rRNA Gene Amplicon Sequences in Human Fecal Samples

(2020) Moira Marizzoni et al.   Frontiers in Microbiology

Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer’s Disease

(2020) Moira Marizzoni et al.   JOURNAL OF ALZHEIMERS DISEASE

Altered microbiomes distinguish Alzheimer’s disease from amnestic mild cognitive impairment and health in a Chinese cohort

(2019) Ping Liu et al.   BRAIN BEHAVIOR AND IMMUNITY

Alzheimer’s Disease Microbiome Is Associated with Dysregulation of the Anti-Inflammatory P-Glycoprotein Pathway

(2019) John P. Haran et al.   mBio

Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2

(2019) Evan Bolyen et al.   NATURE BIOTECHNOLOGY

Mild cognitive impairment has similar alterations as Alzheimer's disease in gut microbiota

(2019) Binyin Li et al.   Alzheimers & Dementia

The relationship between the gut microbiome and mild cognitive impairment in patients without dementia: a cross-sectional study conducted in Japan

(2019) Naoki Saji et al.   Scientific Reports

Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography

(2018) Michelle M. Mielke et al.   Alzheimers & Dementia

Gut Microbiota is Altered in Patients with Alzheimer’s Disease

(2018) Zhen-Qian Zhuang et al.   JOURNAL OF ALZHEIMERS DISEASE

Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer’s disease

(2018) Frederic Brosseron et al.   Alzheimers Research & Therapy

Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer’s Disease Brain: A Review

(2018) Xinhua Zhan et al.   Frontiers in Aging Neuroscience

Can a Bacterial Endotoxin be a Key Factor in the Kinetics of Amyloid Fibril Formation?

(2018) Annalia Asti et al.   JOURNAL OF ALZHEIMERS DISEASE

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression

(2017) Bruce R Stevens et al.   GUT

Microbiology: Gut microbes augment neurodegeneration

(2017) Daniel Erny et al.   NATURE

Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly

(2017) Annamaria Cattaneo et al.   NEUROBIOLOGY OF AGING

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer’s disease-type beta-amyloid neuropathological mechanisms

(2017) Lap Ho et al.   Expert Review of Neurotherapeutics

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease

(2017) Niklas Mattsson et al.   JAMA Neurology

Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

(2017) Laura Bonfili et al.   Scientific Reports

Gut microbiome alterations in Alzheimer’s disease

(2017) Nicholas M. Vogt et al.   Scientific Reports

Alzheimer’s Disease Assessment Scale–Cognitive subscale variants in mild cognitive impairment and mild Alzheimer’s disease: change over time and the effect of enrichment strategies

(2016) Jana Podhorna et al.   Alzheimers Research & Therapy

Assessment of the Incremental Diagnostic Value of Florbetapir F 18 Imaging in Patients With Cognitive Impairment

(2016) Marina Boccardi et al.   JAMA Neurology

Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans

(2016) Shu G. Chen et al.   Scientific Reports

Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling

(2015) Axel Haarmann et al.   ACTA NEUROPATHOLOGICA

A gut-vascular barrier controls the systemic dissemination of bacteria

(2015) Ilaria Spadoni et al.   SCIENCE

Clinical significance of circulating vascular cell adhesion molecule-1 to white matter disintegrity in Alzheimer’s dementia

(2015) Chi-Wei Huang et al.   THROMBOSIS AND HAEMOSTASIS

Sample storage conditions significantly influence faecal microbiome profiles

(2015) Jocelyn M Choo et al.   Scientific Reports

Molecular Links Between Endothelial Dysfunction and Neurodegeneration in Alzheimer's Disease

(2014) Epameinondas Lyros et al.   Current Alzheimer Research

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Impact of Different DNA Extraction Kits and Laboratories upon the Assessment of Human Gut Microbiota Composition by 16S rRNA Gene Sequencing

(2014) Nicholas A. Kennedy et al.   PLoS One

Biomarker Modeling of Alzheimer’s Disease

(2013) Clifford R. Jack et al.   NEURON

P-selectin paradox and dementia of the Alzheimer type: Circulating P-selectin is increased but platelet-bound P-selectin after agonist provocation is compromised

(2013) Petter Järemo et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Intestinal Commensal Microbes as Immune Modulators

(2012) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Inflammation Induced by Infection Potentiates Tau Pathological Features in Transgenic Mice

(2011) Michael Sy et al.   AMERICAN JOURNAL OF PATHOLOGY

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Circulating endotoxin and systemic immune activation in sporadic amyotrophic lateral sclerosis (sALS)

(2008) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

(2008) Jae Lee et al.   Journal of Neuroinflammation

Markers of endothelial dysfunction in older subjects with late onset Alzheimer's disease or vascular dementia

(2008) G. Zuliani et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES