A Mitochondria‐Targeted NIR‐II AIEgen Induced Pyroptosis for Enhanced Tumor Immunotherapy

Pyroptosis Remodeling Tumor Microenvironment to Enhance Pancreatic Cancer Immunotherapy Driven by Membrane Anchoring Photosensitizer

(2022) Meng Wang et al.   Advanced Science

Activation of Pyroptosis by Membrane‐Anchoring AIE Photosensitizer Design: New Prospect for Photodynamic Cancer Cell Ablation

(2021) Min Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tetraarsenic hexoxide enhances generation of mitochondrial ROS to promote pyroptosis by inducing the activation of caspase-3/GSDME in triple-negative breast cancer cells

(2021) Haein An et al.   Cell Death & Disease

An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway

(2021) Xiaomeng Ren et al.   Acta Biomaterialia

Reinforcing the Induction of Immunogenic Cell Death Via Artificial Engineered Cascade Bioreactor‐Enhanced Chemo‐Immunotherapy for Optimizing Cancer Immunotherapy

(2021) Kai Sun et al.   Small

Good Steel Used in the Blade: Well‐Tailored Type‐I Photosensitizers with Aggregation‐Induced Emission Characteristics for Precise Nuclear Targeting Photodynamic Therapy

(2021) Miaomiao Kang et al.   Advanced Science

A Mitochondria‐targeted AIEgen Labelled with 18 F for Breast Cancer Cell Imaging and Therapy

(2021) Kaiwu Yu et al.   Chemistry-An Asian Journal

Aggregation-Induced Emission Photosensitizers: From Molecular Design to Photodynamic Therapy

(2020) Jun Dai et al.   JOURNAL OF MEDICINAL CHEMISTRY

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

(2020) Zhibin Zhang et al.   NATURE

Molecular Engineering to Boost AIE-Active Free Radical Photogenerators and Enable High-Performance Photodynamic Therapy under Hypoxia

(2020) Qing Wan et al.   ADVANCED FUNCTIONAL MATERIALS

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

(2020) Rong Tang et al.   Journal of Hematology & Oncology

Aggregation‐induced Emission Based Fluorogens for Mitochondria‐targeted Tumor Imaging and Theranostics

(2020) Kaiwu Yu et al.   Chemistry-An Asian Journal

Endoplasmic reticulum targeted AIE bioprobe as a highly efficient inducer of immunogenic cell death

(2020) Jun Li et al.   Science China-Chemistry

Acceptor Engineering for Optimized ROS Generation Facilitates Reprogramming Macrophages to M1 Phenotype in Photodynamic Immunotherapy

(2020) Guang Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoparticle-Enhanced Radiotherapy to Trigger Robust Cancer Immunotherapy

(2019) Qian Chen et al.   ADVANCED MATERIALS

Tumor Microenvironment‐Triggered Aggregated Magnetic Nanoparticles for Reinforced Image‐Guided Immunogenic Chemotherapy

(2019) Qinjun Chen et al.   Advanced Science

In Situ Dendritic Cell Vaccine for Effective Cancer Immunotherapy

(2019) Weijing Yang et al.   ACS Nano

Molecular Imaging in the Second Near‐Infrared Window

(2019) Hao Wan et al.   ADVANCED FUNCTIONAL MATERIALS

Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation

(2019) Corey Rogers et al.   Nature Communications

Precise Molecular Engineering of Photosensitizers with Aggregation‐Induced Emission over 800 nm for Photodynamic Therapy

(2019) Wenbo Wu et al.   ADVANCED FUNCTIONAL MATERIALS

Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure

(2019) Chao Chen et al.   ADVANCED MATERIALS

Repurposing Cyanine NIR-I Dyes Accelerates Clinical Translation of Near-Infrared-II (NIR-II) Bioimaging

(2018) Shoujun Zhu et al.   ADVANCED MATERIALS

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging

(2018) Feng Ding et al.   Chemical Science

Bright Near-Infrared Aggregation-Induced Emission Luminogens with Strong Two-Photon Absorption, Excellent Organelle Specificity, and Efficient Photodynamic Therapy Potential

(2018) Zheng Zheng et al.   ACS Nano

Photosensitizers with Aggregation-Induced Emission: Materials and Biomedical Applications

(2018) Fang Hu et al.   ADVANCED MATERIALS

Roles of Caspases in Necrotic Cell Death

(2016) Junying Yuan et al.   CELL

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Substituent Group Variations Directing the Molecular Packing, Electronic Structure, and Aggregation-Induced Emission Property of Isophorone Derivatives

(2013) Zheng Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Pyroptosis: host cell death and inflammation

(2009) Tessa Bergsbaken et al.   NATURE REVIEWS MICROBIOLOGY

New Carbazole-Based Fluorophores: Synthesis, Characterization, and Aggregation-Induced Emission Enhancement

(2008) Shoucheng Dong et al.   JOURNAL OF PHYSICAL CHEMISTRY B