Pyroptosis Remodeling Tumor Microenvironment to Enhance Pancreatic Cancer Immunotherapy Driven by Membrane Anchoring Photosensitizer

Activation of Pyroptosis by Membrane‐Anchoring AIE Photosensitizer Design: New Prospect for Photodynamic Cancer Cell Ablation

(2021) Min Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Promises and challenges of adoptive T-cell therapies for solid tumours

(2021) Matteo Morotti et al.   BRITISH JOURNAL OF CANCER

Charge‐Reversal Polymer Nano‐modulators for Photodynamic Immunotherapy of Cancer

(2021) Shasha He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An NIR‐Fluorophore‐Based Theranostic for Selective Initiation of Tumor Pyroptosis‐Induced Immunotherapy

(2021) Kewei Wang et al.   Small

Pyroptosis, metabolism, and tumor immune microenvironment

(2021) Tiantian Du et al.   Clinical and Translational Medicine

A bioorthogonal system reveals antitumour immune function of pyroptosis

(2020) Qinyang Wang et al.   NATURE

In-vitro analysis of free radical scavenging activities and suppression of LPS-induced ROS production in macrophage cells by Solanum sisymbriifolium extracts

(2020) Garland K. More et al.   Scientific Reports

Immunotherapy for pancreatic cancer: A 2020 update

(2020) Dimitrios Schizas et al.   CANCER TREATMENT REVIEWS

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity

(2020) Rong Tang et al.   Journal of Hematology & Oncology

Pancreatic cancer

(2020) Jonathan D Mizrahi et al.   LANCET

Clinical development and potential of photothermal and photodynamic therapies for cancer

(2020) Xingshu Li et al.   Nature Reviews Clinical Oncology

Resistance Mechanisms of Anti-PD1/PDL1 Therapy in Solid Tumors

(2020) Qingyang Lei et al.   Frontiers in Cell and Developmental Biology

A DNA nanodevice-based vaccine for cancer immunotherapy

(2020) Shaoli Liu et al.   NATURE MATERIALS

Activatable Polymer Nanoenzymes for Photodynamic Immunometabolic Cancer Therapy

(2020) Ziling Zeng et al.   ADVANCED MATERIALS

Extracellular vesicle activities regulating macrophage- and tissue-mediated injury and repair responses

(2020) Qian Hu et al.   Acta Pharmaceutica Sinica B

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers

(2019) Jin-Xuan Fan et al.   NANO LETTERS

Smart Nanovesicle-Mediated Immunogenic Cell Death through Tumor Microenvironment Modulation for Effective Photodynamic Immunotherapy

(2019) Weijing Yang et al.   ACS Nano

Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization

(2018) Binghe Tan et al.   CANCER RESEARCH

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis 

(2018) Bo Zhou et al.   CELL RESEARCH

Tumor-associated macrophages: from basic research to clinical application

(2017) Li Yang et al.   Journal of Hematology & Oncology

Inflammation, Immunity, and Cancer

(2017) Rajesh Singh et al.   MEDIATORS OF INFLAMMATION

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

(2017) Yupeng Wang et al.   NATURE

Stromal biology and therapy in pancreatic cancer: a changing paradigm

(2015) Albrecht Neesse et al.   GUT

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

(2014) Miranda L. Broz et al.   CANCER CELL

Vaccine cure for prostate cancer?

(2011) Alexandra Flemming   NATURE REVIEWS DRUG DISCOVERY

The effects of β-glucan on human immune and cancer cells

(2009) Godfrey Chan et al.   Journal of Hematology & Oncology

Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance

(2009) Michael R. Elliott et al.   NATURE