Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells

Iron accumulation in skeletal muscles of old mice is associated with impaired regeneration after ischaemia–reperfusion damage

(2021) Francesca M. Alves et al.   Journal of Cachexia Sarcopenia and Muscle

Mitochondrial Antioxidant SkQ1 Improves Hypothermic Preservation of the Cornea

(2021) Galina S. Baturina et al.   BIOCHEMISTRY-MOSCOW

SIRT1-autophagy axis inhibits excess iron-induced ferroptosis of foam cells and subsequently increases IL-1Β and IL-18

(2021) Guangming Su et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diflubenzuron leads to apoptotic cell death through ROS generation and mitochondrial dysfunction in bovine mammary epithelial cells

(2021) Woonghee Lee et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Metabolic Syndrome and Sarcopenia

(2021) Hiroki Nishikawa et al.   Nutrients

The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review

(2021) Angelo Armandi et al.   Frontiers in Endocrinology

PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells

(2020) Huan-huan Lv et al.   ACTA PHARMACOLOGICA SINICA

Dysmetabolic iron overload in metabolic syndrome

(2020) Alexandros Sachinidis et al.   CURRENT PHARMACEUTICAL DESIGN

Regulatory Connections between Iron and Glucose Metabolism

(2020) Carine Fillebeen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ROS-Mediated Necroptosis Is Involved in Iron Overload-Induced Osteoblastic Cell Death

(2020) Qing Tian et al.   Oxidative Medicine and Cellular Longevity

Inhibition of JNK-Mediated Autophagy Promotes Proscillaridin A- Induced Apoptosis via ROS Generation, Intracellular Ca+2 Oscillation and Inhibiting STAT3 Signaling in Breast Cancer Cells

(2020) Muhammad Zubair Saleem et al.   Frontiers in Pharmacology

Iron-Induced Apoptotic Cell Death and Autophagy Dysfunction in Human Neuroblastoma Cell Line SH-SY5Y

(2019) Jyotirmoy Rakshit et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Suppression of Alzheimer’s Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study

(2019) Natalia A. Stefanova et al.   Oxidative Medicine and Cellular Longevity

Iron homeostasis and iron-regulated ROS in cell death, senescence and human diseases

(2019) Toshitaka Nakamura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Iron overload inhibits late stage autophagic flux leading to insulin resistance

(2019) James Won Suk Jahng et al.   EMBO REPORTS

Iron Overload Impairs Autophagy: Effects of Rapamycin in Ameliorating Iron-Related Memory Deficits

(2019) Vanise Hallas Uberti et al.   MOLECULAR NEUROBIOLOGY

Iron homeostasis and oxidative stress: An intimate relationship

(2019) Dimitrios Galaris et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ironing the mitochondria: Relevance to its dynamics

(2019) Mamta Upadhyay et al.   MITOCHONDRION

Is Iron Accumulation a Possible Risk Factor for Sarcopenia?

(2018) Guoyang Zhao   BIOLOGICAL TRACE ELEMENT RESEARCH

Apoptosis Induction by Iron Radiation via Inhibition of Autophagy in Trp53+/- Mouse Testes: Is Chronic Restraint-Induced Stress a Modifying Factor?

(2018) Hongyan Li et al.   International Journal of Biological Sciences

Iron deficiency as energetic insult to skeletal muscle in chronic diseases

(2018) Magdalena Dziegala et al.   Journal of Cachexia Sarcopenia and Muscle

Deferasirox selectively induces cell death in the clinically relevant population of leukemic CD34+CD38– cells through iron chelation, induction of ROS, and inhibition of HIF1α expression

(2018) Saar Shapira et al.   EXPERIMENTAL HEMATOLOGY

Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome

(2017) Evgeni Yu. Zernii et al.   Oxidative Medicine and Cellular Longevity

Iron-sulfur clusters in mitochondrial metabolism: Multifaceted roles of a simple cofactor

(2016) Johnny Stiban et al.   BIOCHEMISTRY-MOSCOW

An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells

(2016) Allegra T. Aron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-induced skeletal muscle atrophy involves an Akt-forkhead box O3–E3 ubiquitin ligase-dependent pathway

(2016) Yasumasa Ikeda et al.   JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY

Adiponectin Stimulates Autophagy and Reduces Oxidative Stress to Enhance Insulin Sensitivity During High-Fat Diet Feeding in Mice

(2014) Ying Liu et al.   DIABETES

Aging-related changes in the iron status of skeletal muscle

(2013) Keith C. DeRuisseau et al.   EXPERIMENTAL GERONTOLOGY

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Importance of Iron Chelation in Free Radical-Induced Oxidative Stress and Human Disease

(2011) Klaudia Jomova et al.   CURRENT PHARMACEUTICAL DESIGN

A novel quantitative flow cytometry-based assay for autophagy

(2010) Kai Er Eng et al.   Autophagy

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

(2009) Emanuele Marzetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy

(2008) Tim Hofer et al.   EXPERIMENTAL GERONTOLOGY