Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects
Authors
Keywords
-
Journal
NEURON
Volume 111, Issue 8, Pages 1191-1204.e5
Publisher
Elsevier BV
Online
2023-02-09
DOI
10.1016/j.neuron.2023.01.010
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation
- (2022) Elisa Giacomelli et al. Cell Stem Cell
- iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders
- (2022) Hideyuki Okano et al. Cell Stem Cell
- Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines
- (2022) Emily G. Baxi et al. NATURE NEUROSCIENCE
- TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
- (2022) Anna-Leigh Brown et al. NATURE
- TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A
- (2022) X. Rosa Ma et al. NATURE
- Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome
- (2021) Alejandro J. Brenes et al. Cell Reports
- Addressing heterogeneity in amyotrophic lateral sclerosis CLINICAL TRIALS
- (2020) Namita A. Goyal et al. MUSCLE & NERVE
- ALS phenotype is influenced by age, sex, and genetics
- (2020) Adriano Chiò et al. NEUROLOGY
- Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936
- (2020) Jamie Toombs et al. Stem Cell Research
- A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis
- (2020) Ryoichi Nakamura et al. Communications Biology
- Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures
- (2020) Ritchie Ho et al. Cell Systems
- ALS-implicated protein TDP-43 sustains levels of STMN2, a mediator of motor neuron growth and repair
- (2019) Joseph R. Klim et al. NATURE NEUROSCIENCE
- Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration
- (2019) Ze’ev Melamed et al. NATURE NEUROSCIENCE
- Global Characterization of X Chromosome Inactivation in Human Pluripotent Stem Cells
- (2019) Shiran Bar et al. Cell Reports
- Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming
- (2019) Adrian Janiszewski et al. GENOME RESEARCH
- Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
- (2018) Yingxiao Shi et al. NATURE MEDICINE
- The S100B story: From biomarker to active factor in neural injury
- (2018) Fabrizio Michetti et al. JOURNAL OF NEUROCHEMISTRY
- Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent
- (2018) Koki Fujimori et al. NATURE MEDICINE
- Landscape of X chromosome inactivation across human tissues
- (2017) Taru Tukiainen et al. NATURE
- Secular Trends of Amyotrophic Lateral Sclerosis
- (2017) Adriano Chiò et al. JAMA Neurology
- variancePartition: interpreting drivers of variation in complex gene expression studies
- (2016) Gabriel E. Hoffman et al. BMC BIOINFORMATICS
- A rapid functional decline type of amyotrophic lateral sclerosis is linked to low expression ofTTN
- (2016) Hazuki Watanabe et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Modeling ALS with motor neurons derived from human induced pluripotent stem cells
- (2016) Samuel Sances et al. NATURE NEUROSCIENCE
- Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential
- (2016) Aija Kyttälä et al. Stem Cell Reports
- Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS
- (2016) Daniel Cacabelos et al. Acta Neuropathologica Communications
- Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS
- (2015) Mercedes Prudencio et al. NATURE NEUROSCIENCE
- Derivation of Ethnically Diverse Human Induced Pluripotent Stem Cell Lines
- (2015) Eun Ah Chang et al. Scientific Reports
- Reduced C9orf72 protein levels in frontal cortex of amyotrophic lateral sclerosis and frontotemporal degeneration brain with the C9ORF72 hexanucleotide repeat expansion
- (2014) Adrian J. Waite et al. NEUROBIOLOGY OF AGING
- RNA Toxicity from the ALS/FTD C9ORF72 Expansion Is Mitigated by Antisense Intervention
- (2013) Christopher J. Donnelly et al. NEURON
- SERE: Single-parameter quality control and sample comparison for RNA-Seq
- (2012) Stefan K Schulze et al. BMC GENOMICS
- An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
- (2012) Keisuke Okita et al. STEM CELLS
- A functional variant in ZNF512B is associated with susceptibility to amyotrophic lateral sclerosis in Japanese
- (2011) Aritoshi Iida et al. HUMAN MOLECULAR GENETICS
- A more efficient method to generate integration-free human iPS cells
- (2011) Keisuke Okita et al. NATURE METHODS
- Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS
- (2011) Mariely DeJesus-Hernandez et al. NEURON
- Generation of Induced Pluripotent Stem Cells from CD34+ Cells across Blood Drawn from Multiple Donors with Non-Integrating Episomal Vectors
- (2011) Amanda A. Mack et al. PLoS One
- The sex ratio in amyotrophic lateral sclerosis: A population based study
- (2010) Zita R. Manjaly et al. Amyotrophic Lateral Sclerosis
- Female Human iPSCs Retain an Inactive X Chromosome
- (2010) Jason Tchieu et al. Cell Stem Cell
- Effects of gender in amyotrophic lateral sclerosis
- (2010) Pamela A. McCombe et al. Gender Medicine
- Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients
- (2009) Christiaan GJ Saris et al. BMC GENOMICS
- Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
- (2009) J. Yu et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now