Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming

Nuclear positioning and pairing of X-chromosome inactivation centers are not primary determinants during initiation of random X-inactivation

(2019) Tim Pollex et al.   NATURE GENETICS

X-Chromosome Dosage Modulates Multiple Molecular and Cellular Properties of Mouse Pluripotent Stem Cells Independently of Global DNA Methylation Levels

(2019) Juan Song et al.   Stem Cell Reports

Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming

(2019) Geoffrey Schiebinger et al.   CELL

Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation

(2019) Irene Talon et al.   Frontiers in Cell and Developmental Biology

Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming

(2018) Benjamin A. Schwarz et al.   Cell Stem Cell

X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs

(2018) Vincent Pasque et al.   Stem Cell Reports

X-Chromosome Inactivation: A Crossroads Between Chromosome Architecture and Gene Regulation

(2018) Rafael Galupa et al.   Annual Review of Genetics

The Implication of Early Chromatin Changes in X Chromosome Inactivation

(2018) Jan Jakub Żylicz et al.   CELL

The non-canonical SMC protein SmcHD1 antagonises TAD formation and compartmentalisation on the inactive X chromosome

(2018) Michal R. Gdula et al.   Nature Communications

Insights into the Establishment of Chromatin States in Pluripotent Cells from Studies of X Inactivation

(2017) Andreas Postlmayr et al.   JOURNAL OF MOLECULAR BIOLOGY

Single-cell mRNA quantification and differential analysis with Census

(2017) Xiaojie Qiu et al.   NATURE METHODS

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

The X chromosome in space

(2017) Teddy Jégu et al.   NATURE REVIEWS GENETICS

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

(2017) Maud Borensztein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease

(2017) Irene Cantone et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A mixed modality approach towards Xi reactivation for Rett syndrome and other X-linked disorders

(2017) Lieselot L. G. Carrette et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic plasticity and the hallmarks of cancer

(2017) William A. Flavahan et al.   SCIENCE

Contribution of epigenetic landscapes and transcription factors to X-chromosome reactivation in the inner cell mass

(2017) Maud Borensztein et al.   Nature Communications

Xist-dependent imprinted X inactivation and the early developmental consequences of its failure

(2017) Maud Borensztein et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Gender Differences in Global but Not Targeted Demethylation in iPSC Reprogramming

(2017) Inês Milagre et al.   Cell Reports

Structural organization of the inactive X chromosome in the mouse

(2016) Luca Giorgetti et al.   NATURE

Random monoallelic expression of genes on autosomes: Parallels with X-chromosome inactivation

(2016) Anne-Valerie Gendrel et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Escape Artists of the X Chromosome

(2016) Bradley P. Balaton et al.   TRENDS IN GENETICS

Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

(2016) Irene Cantone et al.   Nature Communications

X chromosome reactivation in reprogramming and in development

(2015) Vincent Pasque et al.   CURRENT OPINION IN CELL BIOLOGY

A high-throughput screen of inactive X chromosome reactivation identifies the enhancement of DNA demethylation by 5-aza-2′-dC upon inhibition of ribonucleotide reductase

(2015) Alissa Minkovsky et al.   Epigenetics & Chromatin

X Chromosome Reactivation Dynamics Reveal Stages of Reprogramming to Pluripotency

(2014) Vincent Pasque et al.   CELL

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

Full-length RNA-seq from single cells using Smart-seq2

(2014) Simone Picelli et al.   Nature Protocols

Genetic and pharmacological reactivation of the mammalian inactive X chromosome

(2014) S. Bhatnagar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections

(2014) Rekin's Janky et al.   PLoS Computational Biology

Tsix RNA and the Germline Factor, PRDM14, Link X Reactivation and Stem Cell Reprogramming

(2013) Bernhard Payer et al.   MOLECULAR CELL

Genomic imprinting is variably lost during reprogramming of mouse iPS cells

(2013) Sachiko Takikawa et al.   Stem Cell Research

ZBTB33 binds unmethylated regions of the genome associated with actively expressed genes

(2013) Adam Blattler et al.   Epigenetics & Chromatin

The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo

(2013) Alissa Minkovsky et al.   Cell Reports

Single-Cell Expression Analyses during Cellular Reprogramming Reveal an Early Stochastic and a Late Hierarchic Phase

(2012) Yosef Buganim et al.   CELL

Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations

(2012) S. F. Pinter et al.   GENOME RESEARCH

Advances in understanding chromosome silencing by the long non-coding RNA Xist

(2012) T. Sado et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Coupling of X-Chromosome Inactivation to Pluripotency

(2011) Jane Lynda Deuve et al.   Annual Review of Cell and Developmental Biology

YY1 Tethers Xist RNA to the Inactive X Nucleation Center

(2011) Yesu Jeon et al.   CELL

Histone variant macroH2A confers resistance to nuclear reprogramming

(2011) Vincent Pasque et al.   EMBO JOURNAL

The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA

(2011) E. Splinter et al.   GENES & DEVELOPMENT

LINE-1 Activity in Facultative Heterochromatin Formation during X Chromosome Inactivation

(2010) Jennifer C. Chow et al.   CELL

Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

(2010) Alessia Peserico et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

(2010) Ziyang Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

High-resolution analysis of epigenetic changes associated with X inactivation

(2009) H. Marks et al.   GENOME RESEARCH

The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting

(2009) Mary E. Donohoe et al.   NATURE

Defining Molecular Cornerstones during Fibroblast to iPS Cell Reprogramming in Mouse

(2008) Matthias Stadtfeld et al.   Cell Stem Cell

X Chromosome Activity in Mouse XX Primordial Germ Cells

(2008) Susana M. Chuva de Sousa Lopes et al.   PLoS Genetics

Molecular Coupling of Xist Regulation and Pluripotency

(2008) P. Navarro et al.   SCIENCE

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE