A high-dimensional microfluidic approach for selection of aptamers with programmable binding affinities

Wearable aptamer-field-effect transistor sensing system for noninvasive cortisol monitoring

(2022) Bo Wang et al.   Science Advances

Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples

(2022) Liqian Wang et al.   Nature Biomedical Engineering

Efficient recovery of potent tumour-infiltrating lymphocytes through quantitative immunomagnetic cell sorting

(2022) Zongjie Wang et al.   Nature Biomedical Engineering

Aptamers from random sequence space: Accomplishments, gaps and future considerations

(2022) Shuwen Qian et al.   ANALYTICA CHIMICA ACTA

Ultrasensitive Detection and Depletion of Rare Leukemic B Cells in T Cell Populations via Immunomagnetic Cell Ranking

(2021) Zongjie Wang et al.   ANALYTICAL CHEMISTRY

Recombinant Antibody Engineering Enables Reversible Binding for Continuous Protein Biosensing

(2021) Christian Fercher et al.   ACS Sensors

Seconds-Resolved, In Situ Measurements of Plasma Phenylalanine Disposition Kinetics in Living Rats

(2021) Andrea Idili et al.   ANALYTICAL CHEMISTRY

Reagentless biomolecular analysis using a molecular pendulum

(2021) Jagotamoy Das et al.   Nature Chemistry

High Affinity Dimeric Aptamers Enable Rapid Electrochemical Detection of Wild‐Type and B.1.1.7 SARS‐CoV‐2 in Unprocessed Saliva

(2021) Zijie Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diverse high-affinity DNA aptamers for wild-type and B.1.1.7 SARS-CoV-2 spike proteins from a pre-structured DNA library

(2021) Jiuxing Li et al.   NUCLEIC ACIDS RESEARCH

Implantable aptamer–field-effect transistor neuroprobes for in vivo neurotransmitter monitoring

(2021) Chuanzhen Zhao et al.   Science Advances

Re-Evaluating the Conventional Wisdom about Binding Assays

(2020) Brandon D. Wilson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Ultrasensitive and rapid quantification of rare tumorigenic stem cells in hPSC-derived cardiomyocyte populations

(2020) Zongjie Wang et al.   Science Advances

Tracking the expression of therapeutic protein targets in rare cells by antibody-mediated nanoparticle labelling and magnetic sorting

(2020) Mahmoud Labib et al.   Nature Biomedical Engineering

Solid-state nanopore sensors

(2020) Liang Xue et al.   Nature Reviews Materials

Beating the reaction limits of biosensor sensitivity with dynamic tracking of single binding events

(2019) Derin Sevenler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Click-Particle Display for Base-Modified Aptamer Discovery

(2019) Chelsea K.L. Gordon et al.   ACS Chemical Biology

The Era of Digital Health: A Review of Portable and Wearable Affinity Biosensors

(2019) Jiaobing Tu et al.   ADVANCED FUNCTIONAL MATERIALS

Single-cell mRNA cytometry via sequence-specific nanoparticle clustering and trapping

(2018) Mahmoud Labib et al.   Nature Chemistry

Identification and characterization of nucleobase-modified aptamers by click-SELEX

(2018) Franziska Pfeiffer et al.   Nature Protocols

Aptamer–field-effect transistors overcome Debye length limitations for small-molecule sensing

(2018) Nako Nakatsuka et al.   SCIENCE

Recognition-Enhanced Metastably Shielded Aptamer for Digital Quantification of Small Molecules

(2018) Ruijie Deng et al.   ANALYTICAL CHEMISTRY

Three decades of nucleic acid aptamer technologies: Lessons learned, progress and opportunities on aptamer development

(2018) Tao Wang et al.   BIOTECHNOLOGY ADVANCES

Selection of DNA aptamers with two modified bases

(2017) Bharat N. Gawande et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-time measurement of small molecules directly in awake, ambulatory animals

(2017) Netzahualcóyotl Arroyo-Currás et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Closed-loop control of circulating drug levels in live animals

(2017) P. L. Mage et al.   Nature Biomedical Engineering

Aptamers Facilitating Amplified Detection of Biomolecules

(2014) Feng Li et al.   ANALYTICAL CHEMISTRY

Particle Display: A Quantitative Screening Method for Generating High-Affinity Aptamers

(2014) Jinpeng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Real-Time, Aptamer-Based Tracking of Circulating Therapeutic Agents in Living Animals

(2013) B. S. Ferguson et al.   Science Translational Medicine

Engineering Biosensors with Extended, Narrowed, or Arbitrarily Edited Dynamic Range

(2011) Alexis Vallée-Bélisle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Usefulness of Myeloperoxidase Levels in Healthy Elderly Subjects to Predict Risk of Developing Heart Failure

(2009) W.H. Wilson Tang et al.   AMERICAN JOURNAL OF CARDIOLOGY

Functional Nucleic Acid Sensors

(2009) Juewen Liu et al.   CHEMICAL REVIEWS

Micromagnetic selection of aptamers in microfluidic channels

(2009) X. Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamer-based biosensors

(2007) Shiping Song et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY