Precise integration of large DNA sequences in plant genomes using PrimeRoot editors

RicENN: Prediction of Rice Enhancers with Neural Network Based on DNA Sequences

(2022) Yujia Gao et al.   Interdisciplinary Sciences-Computational Life Sciences

An engineered prime editor with enhanced editing efficiency in plants

(2022) Yuan Zong et al.   NATURE BIOTECHNOLOGY

Efficient targeted insertion of large DNA fragments without DNA donors

(2022) Jinlin Wang et al.   NATURE METHODS

Target lines for recombinase-mediated gene stacking in soybean

(2022) Li Jiang et al.   THEORETICAL AND APPLIED GENETICS

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

(2022) Matthew T. N. Yarnall et al.   NATURE BIOTECHNOLOGY

Genome engineering for crop improvement and future agriculture

(2021) Caixia Gao   CELL

High-efficiency prime editing with optimized, paired pegRNAs in plants

(2021) Qiupeng Lin et al.   NATURE BIOTECHNOLOGY

Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing

(2021) Mitchell L. Leibowitz et al.   NATURE GENETICS

Poaceae-specific cell wall-derived oligosaccharides activate plant immunity via OsCERK1 during Magnaporthe oryzae infection in rice

(2021) Chao Yang et al.   Nature Communications

Engineered pegRNAs improve prime editing efficiency

(2021) James W. Nelson et al.   NATURE BIOTECHNOLOGY

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

(2021) Andrew V. Anzalone et al.   NATURE BIOTECHNOLOGY

Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9

(2020) Oliver Xiaoou Dong et al.   Nature Communications

Prime genome editing in rice and wheat

(2020) Qiupeng Lin et al.   NATURE BIOTECHNOLOGY

Complex Trait Loci in Maize Enabled by CRISPR-Cas9 Mediated Gene Insertion

(2020) Huirong Gao et al.   Frontiers in Plant Science

Efficient generation of mouse models with the prime editing system

(2020) Yao Liu et al.   Cell Discovery

Targeted, efficient sequence insertion and replacement in rice

(2020) Yuming Lu et al.   NATURE BIOTECHNOLOGY

High-Resolution Mapping of Multiway Enhancer-Promoter Interactions Regulating Pathogen Detection

(2020) Pranitha Vangala et al.   MOLECULAR CELL

CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering

(2020) Phuc Leo H. Vo et al.   NATURE BIOTECHNOLOGY

CRISPR-Cas9 genome editing induces megabase-scale chromosomal truncations

(2019) Grégoire Cullot et al.   Nature Communications

Long-range enhancer–promoter contacts in gene expression control

(2019) Stefan Schoenfelder et al.   NATURE REVIEWS GENETICS

RNA-guided DNA insertion with CRISPR-associated transposases

(2019) Jonathan Strecker et al.   SCIENCE

Global Quantitative Mapping of Enhancers in Rice by STARR-seq

(2019) Jialei Sun et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Transgene Stacking as Effective Tool for Enhanced Disease Resistance in Plants

(2019) Kashmala Shehryar et al.   MOLECULAR BIOTECHNOLOGY

Genome sequence of the model rice variety KitaakeX

(2019) Rashmi Jain et al.   BMC GENOMICS

Search-and-replace genome editing without double-strand breaks or donor DNA

(2019) Andrew V. Anzalone et al.   NATURE

CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing

(2019) Hakim Manghwar et al.   TRENDS IN PLANT SCIENCE

Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements

(2018) Michael Kosicki et al.   NATURE BIOTECHNOLOGY

Agrobacterium-mediated horizontal gene transfer: Mechanism, biotechnological application, potential risk and forestalling strategy

(2018) Minliang Guo et al.   BIOTECHNOLOGY ADVANCES

Options for keeping the food system within environmental limits

(2018) Marco Springmann et al.   NATURE

miRBase: from microRNA sequences to function

(2018) Ana Kozomara et al.   NUCLEIC ACIDS RESEARCH

Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion

(2017) Yuan Zong et al.   NATURE BIOTECHNOLOGY

The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis

(2017) Paul Schimmel   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance

(2017) Yiwen Deng et al.   SCIENCE

Pyramiding resistance-conferring gene sequences in crops

(2017) Marc Fuchs   Current Opinion in Virology

Cre Recombinase and Other Tyrosine Recombinases

(2016) Gretchen Meinke et al.   CHEMICAL REVIEWS

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

Creation of fragrant rice by targeted knockout of theOsBADH2gene using TALEN technology

(2015) Qiwei Shan et al.   PLANT BIOTECHNOLOGY JOURNAL

The long road to recombinase-mediated plant transformation

(2015) David W. Ow   PLANT BIOTECHNOLOGY JOURNAL

Epigenetic silencing in transgenic plants

(2015) Sarma Rajeevkumar et al.   Frontiers in Plant Science

Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew

(2014) Yanpeng Wang et al.   NATURE BIOTECHNOLOGY

Genome editing in rice and wheat using the CRISPR/Cas system

(2014) Qiwei Shan et al.   Nature Protocols

PNRD: a plant non-coding RNA database

(2014) Xin Yi et al.   NUCLEIC ACIDS RESEARCH

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Site-specific recombinases as tools for heterologous gene integration

(2011) Nobutaka Hirano et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Recombinase technology: applications and possibilities

(2010) Yueju Wang et al.   PLANT CELL REPORTS

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

(2009) Vipula K. Shukla et al.   NATURE

PMRD: plant microRNA database

(2009) Zhenhai Zhang et al.   NUCLEIC ACIDS RESEARCH