Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeted DNA integration in human cells without double-strand breaks using CRISPR-associated transposases
Authors
Keywords
-
Journal
NATURE BIOTECHNOLOGY
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-03-30
DOI
10.1038/s41587-023-01748-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Precise cut-and-paste DNA insertion using engineered type V-K CRISPR-associated transposases
- (2023) Connor J. Tou et al. NATURE BIOTECHNOLOGY
- Evolutionary and mechanistic diversity of Type I-F CRISPR-associated transposons
- (2022) Sanne E. Klompe et al. MOLECULAR CELL
- Structural basis for DNA targeting by the Tn7 transposon
- (2022) Yao Shen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Selective TnsC recruitment enhances the fidelity of RNA-guided transposition
- (2022) Florian T. Hoffmann et al. NATURE
- Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
- (2022) Matthew G. Durrant et al. NATURE BIOTECHNOLOGY
- Structural basis for the assembly of the type V CRISPR-associated transposon complex
- (2022) Michael Schmitz et al. CELL
- Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases
- (2022) Matthew T. N. Yarnall et al. NATURE BIOTECHNOLOGY
- Dual modes of CRISPR-associated transposon homing
- (2021) Makoto Saito et al. CELL
- Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing
- (2021) Mitchell L. Leibowitz et al. NATURE GENETICS
- Programmable RNA targeting with the single-protein CRISPR effector Cas7-11
- (2021) Ahsen Özcan et al. NATURE
- Structural basis for target site selection in RNA-guided DNA transposition systems
- (2021) Jung-Un Park et al. SCIENCE
- Unbiased profiling of CRISPR RNA-guided transposition products by long-read sequencing
- (2021) Phuc Leo H. Vo et al. Mobile DNA
- CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-seq Analysis
- (2021) Xintao Qiu et al. GENOMICS PROTEOMICS & BIOINFORMATICS
- The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair
- (2021) Richard O. Adeyemi et al. MOLECULAR CELL
- Target site selection and remodelling by type V CRISPR-transposon systems
- (2021) Irma Querques et al. NATURE
- Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing
- (2021) Andrew V. Anzalone et al. NATURE BIOTECHNOLOGY
- RNA-guided retargeting of Sleeping Beauty transposition in human cells
- (2020) Adrian Kovač et al. eLife
- Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
- (2020) Andrew V. Anzalone et al. NATURE BIOTECHNOLOGY
- Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
- (2020) Yuxi Chen et al. Nature Communications
- Targeted RNA Knockdown by a Type III CRISPR-Cas Complex in Zebrafish
- (2020) Thomas Fricke et al. CRISPR Journal
- Guide RNA Categorization Enables Target Site Choice in Tn7-CRISPR-Cas Transposons
- (2020) Michael T. Petassi et al. CELL
- Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos
- (2020) Michael V. Zuccaro et al. CELL
- CRISPR RNA-guided integrases for high-efficiency, multiplexed bacterial genome engineering
- (2020) Phuc Leo H. Vo et al. NATURE BIOTECHNOLOGY
- Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas
- (2019) Adam E. Dolan et al. MOLECULAR CELL
- The next generation of CRISPR–Cas technologies and applications
- (2019) Adrian Pickar-Oliver et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Approaches to study CRISPR RNA biogenesis and the key players involved
- (2019) Juliane Behler et al. METHODS
- Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration
- (2019) Sanne E. Klompe et al. NATURE
- RNA-guided DNA insertion with CRISPR-associated transposases
- (2019) Jonathan Strecker et al. SCIENCE
- The ENCODE Blacklist: Identification of Problematic Regions of the Genome
- (2019) Haley M. Amemiya et al. Scientific Reports
- The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
- (2019) Daniel N. Weinberg et al. NATURE
- Targeted transcriptional modulation with type I CRISPR–Cas systems in human cells
- (2019) Adrian Pickar-Oliver et al. NATURE BIOTECHNOLOGY
- Search-and-replace genome editing without double-strand breaks or donor DNA
- (2019) Andrew V. Anzalone et al. NATURE
- A highly soluble Sleeping Beauty transposase improves control of gene insertion
- (2019) Irma Querques et al. NATURE BIOTECHNOLOGY
- Harnessing type I CRISPR–Cas systems for genome engineering in human cells
- (2019) Peter Cameron et al. NATURE BIOTECHNOLOGY
- Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system
- (2019) Tyler S. Halpin-Healy et al. NATURE
- Advances in genome editing through control of DNA repair pathways
- (2019) Charles D. Yeh et al. NATURE CELL BIOLOGY
- Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- An enhanced CRISPR repressor for targeted mammalian gene regulation
- (2018) Nan Cher Yeo et al. NATURE METHODS
- A multi-landing pad DNA integration platform for mammalian cell engineering
- (2018) Leonid Gaidukov et al. NUCLEIC ACIDS RESEARCH
- Transcription-coupled changes in nuclear mobility of mammalian cis-regulatory elements
- (2018) Bo Gu et al. SCIENCE
- Large deletions induced by Cas9 cleavage
- (2018) Fatwa Adikusuma et al. NATURE
- CRISPR-Cas guides the future of genetic engineering
- (2018) Gavin J. Knott et al. SCIENCE
- Systematic Screening of Commonly Used Commercial Transfection Reagents towards Efficient Transfection of Single-Stranded Oligonucleotides
- (2018) Tao Wang et al. MOLECULES
- Transposons: Moving Forward from Preclinical Studies to Clinical Trials
- (2017) Jaitip Tipanee et al. HUMAN GENE THERAPY
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
- (2017) Y Bill Kim et al. NATURE BIOTECHNOLOGY
- Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells
- (2017) Wentian Luo et al. NUCLEIC ACIDS RESEARCH
- Imaging Specific Genomic DNA in Living Cells
- (2016) Baohui Chen et al. Annual Review of Biophysics
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- Lentiviral vectors, two decades later
- (2016) L. Naldini et al. SCIENCE
- Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
- (2015) Silvana Konermann et al. NATURE
- Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
- (2015) Van Trung Chu et al. NATURE BIOTECHNOLOGY
- Highly efficient Cas9-mediated transcriptional programming
- (2015) Alejandro Chavez et al. NATURE METHODS
- Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements
- (2015) Pratiksha I Thakore et al. NATURE METHODS
- A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
- (2014) Marvin E. Tanenbaum et al. CELL
- Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes
- (2014) Mark D. Szczelkun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microhomology-mediated end-joining-dependent integration of donor DNA in cells and animals using TALENs and CRISPR/Cas9
- (2014) Shota Nakade et al. Nature Communications
- Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
- (2014) Steven Lin et al. eLife
- CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
- (2013) Luke A. Gilbert et al. CELL
- CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering
- (2013) Prashant Mali et al. NATURE BIOTECHNOLOGY
- RNA-guided gene activation by CRISPR-Cas9–based transcription factors
- (2013) Pablo Perez-Pinera et al. NATURE METHODS
- AAA+ Proteases: ATP-Fueled Machines of Protein Destruction
- (2011) Robert T. Sauer et al. Annual Review of Biochemistry
- ClpXP, an ATP-powered unfolding and protein-degradation machine
- (2011) Tania A. Baker et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Integrative genomics viewer
- (2011) James T Robinson et al. NATURE BIOTECHNOLOGY
- A hyperactive piggyBac transposase for mammalian applications
- (2011) K. Yusa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of Homologous Recombination in Eukaryotes
- (2010) Wolf-Dietrich Heyer et al. Annual Review of Genetics
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Architecture of the Tn7 Posttransposition Complex: An Elaborate Nucleoprotein Structure
- (2010) Jason W. Holder et al. JOURNAL OF MOLECULAR BIOLOGY
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
- (2010) Mary Ellen Moynahan et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Sequence Alignment/Map format and SAMtools
- (2009) H. Li et al. BIOINFORMATICS
- Unique Contacts Direct High-Priority Recognition of the Tetrameric Mu Transposase-DNA Complex by the AAA+ Unfoldase ClpX
- (2008) Aliaa H. Abdelhakim et al. MOLECULAR CELL
- Model-based Analysis of ChIP-Seq (MACS)
- (2008) Yong Zhang et al. GENOME BIOLOGY
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started