Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

(2014) Hiroshi Nishimasu et al.   CELL

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9

(2014) Samuel H. Sternberg et al.   NATURE

In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus

(2013) Tomas Sinkunas et al.   EMBO JOURNAL

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

crRNA and tracrRNA guide Cas9-mediated DNA interference inStreptococcus thermophilus

(2013) Tautvydas Karvelis et al.   RNA Biology

The Helicase-Like Domains of Type III Restriction Enzymes Trigger Long-Range Diffusion Along DNA

(2013) F. W. Schwarz et al.   SCIENCE

Transcription Under Torsion

(2013) J. Ma et al.   SCIENCE

Probing the Elasticity of DNA on Short Length Scales by Modeling Supercoiling under Tension

(2012) Robert Schöpflin et al.   BIOPHYSICAL JOURNAL

Structure and Mechanism of the CMR Complex for CRISPR-Mediated Antiviral Immunity

(2012) Jing Zhang et al.   MOLECULAR CELL

CRISPR Immunity Relies on the Consecutive Binding and Degradation of Negatively Supercoiled Invader DNA by Cascade and Cas3

(2012) Edze R. Westra et al.   MOLECULAR CELL

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

(2012) Dipali G. Sashital et al.   MOLECULAR CELL

Initiation of transcription-coupled repair characterized at single-molecule resolution

(2012) Kévin Howan et al.   NATURE

Nicking enzyme–based internal labeling of DNA at multiple loci

(2012) Nicholas Luzzietti et al.   Nature Protocols

Torque measurements reveal sequence-specific cooperative transitions in supercoiled DNA

(2012) F. C. Oberstrass et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system

(2011) Tomas Sinkunas et al.   EMBO JOURNAL

Direct Mechanical Measurements Reveal the Material Properties of Three-Dimensional DNA Origami

(2011) Dominik J. Kauert et al.   NANO LETTERS

Structures of the RNA-guided surveillance complex from a bacterial immune system

(2011) Blake Wiedenheft et al.   NATURE

Evolution and classification of the CRISPR–Cas systems

(2011) Kira S. Makarova et al.   NATURE REVIEWS MICROBIOLOGY

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

(2011) Matthijs M Jore et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions

(2011) B. Wiedenheft et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

(2011) E. Semenova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energetics at the DNA Supercoiling Transition

(2010) Hergen Brutzer et al.   BIOPHYSICAL JOURNAL

The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

(2010) Josiane E. Garneau et al.   NATURE

Torsional sensing of small-molecule binding using magnetic tweezers

(2010) J. Lipfert et al.   NUCLEIC ACIDS RESEARCH

Mechanical and structural properties of YOYO-1 complexed DNA

(2010) K. Gunther et al.   NUCLEIC ACIDS RESEARCH

DNA–DNA Interactions in Tight Supercoils Are Described by a Small Effective Charge Density

(2010) Christopher Maffeo et al.   PHYSICAL REVIEW LETTERS

RNA-Guided RNA Cleavage by a CRISPR RNA-Cas Protein Complex

(2009) Caryn R. Hale et al.   CELL

Torsional Stiffness of Single Superparamagnetic Microspheres in an External Magnetic Field

(2009) Daniel Klaue et al.   PHYSICAL REVIEW LETTERS

Measurement of the Torque on a Single Stretched and Twisted DNA Using Magnetic Tweezers

(2009) Francesco Mosconi et al.   PHYSICAL REVIEW LETTERS

Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes

(2008) J. Carte et al.   GENES & DEVELOPMENT

Abrupt Buckling Transition Observed during the Plectoneme Formation of Individual DNA Molecules

(2008) Scott Forth et al.   PHYSICAL REVIEW LETTERS

Small CRISPR RNAs Guide Antiviral Defense in Prokaryotes

(2008) S. J. J. Brouns et al.   SCIENCE