A druggable copper-signalling pathway that drives inflammation

Copper induces cell death by targeting lipoylated TCA cycle proteins

(2022) Peter Tsvetkov et al.   SCIENCE

Macrophages in health and disease

(2022) Matthew D. Park et al.   CELL

Does tissue imprinting restrict macrophage plasticity?

(2021) Martin Guilliams et al.   NATURE IMMUNOLOGY

Hallmarks of health

(2021) Carlos López-Otín et al.   CELL

A mild and straightforward one-pot hyaluronic acid functionalization through termination of poly-(2-alkyl-2-oxazoline)

(2021) Mathieu Madau et al.   POLYMER

Persister cancer cells: Iron addiction and vulnerability to ferroptosis

(2021) Raphaël Rodriguez et al.   MOLECULAR CELL

The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences

(2021) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study

(2020) Kristina E Rudd et al.   LANCET

Benefits of Metformin in Attenuating the Hallmarks of Aging

(2020) Ameya S. Kulkarni et al.   Cell Metabolism

Metformin Enhances Autophagy and Normalizes Mitochondrial Function to Alleviate Aging-Associated Inflammation

(2020) Leena P. Bharath et al.   Cell Metabolism

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Cytokine release syndrome in severe COVID-19

(2020) John B. Moore et al.   SCIENCE

Phagosomal removal of fungal melanin reprograms macrophage metabolism to promote antifungal immunity

(2020) Samuel M. Gonçalves et al.   Nature Communications

COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

(2020) Robert Lorenz Chua et al.   NATURE BIOTECHNOLOGY

CD44 regulates epigenetic plasticity by mediating iron endocytosis

(2020) Sebastian Müller et al.   Nature Chemistry

Dexamethasone in Hospitalized Patients with Covid-19 — Preliminary Report

(2020)   NEW ENGLAND JOURNAL OF MEDICINE

Mitochondrial copper depletion suppresses triple-negative breast cancer in mice

(2020) Liyang Cui et al.   NATURE BIOTECHNOLOGY

The evolving metabolic landscape of chromatin biology and epigenetics

(2020) Ziwei Dai et al.   NATURE REVIEWS GENETICS

The metabolomic signature of extreme longevity: naked mole rats versus mice

(2019) Mélanie Viltard et al.   Aging-US

Hydrocortisone plus Fludrocortisone for Adults with Septic Shock

(2018) Djillali Annane et al.   NEW ENGLAND JOURNAL OF MEDICINE

Visualizing biologically active small molecules in cells using click chemistry

(2018) Tatiana Cañeque et al.   Nature Reviews Chemistry

[Cu(H2O) n ]2+ (n = 1–6) complexes in solution phase: a DFT hierarchical study

(2017) Emir A. Galván-García et al.   THEORETICAL CHEMISTRY ACCOUNTS

Software update: the ORCA program system, version 4.0

(2017) Frank Neese   Wiley Interdisciplinary Reviews-Computational Molecular Science

Fast and Accurate Protein False Discovery Rates on Large-Scale Proteomics Data Sets with Percolator 3.0

(2016) Matthew The et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

Dual Transcriptome Profiling of Leishmania -Infected Human Macrophages Reveals Distinct Reprogramming Signatures

(2016) Maria Cecilia Fernandes et al.   mBio

First-in-human phase I clinical trial of RG7356, an anti-CD44 humanized antibody, in patients with advanced, CD44-expressing solid tumors

(2016) C. Willemien Menke-van der Houven van Oordt et al.   Oncotarget

Widespread Shortening of 3’ Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection

(2016) Athma A. Pai et al.   PLoS Genetics

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

A dual-emission fluorescence-enhanced probe for imaging copper(ii) ions in lysosomes

(2015) Mingguang Ren et al.   Journal of Materials Chemistry B

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity

(2014) S. Saeed et al.   SCIENCE

Oral Disinfectants Inhibit Protein-Protein Interactions Mediated by the Anti-Apoptotic Protein Bcl-xLand Induce Apoptosis in Human Oral Tumor Cells

(2013) Martin Gräber et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Optimization of parameters for semiempirical methods VI: more modifications to the NDDO approximations and re-optimization of parameters

(2012) James J. P. Stewart   JOURNAL OF MOLECULAR MODELING

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

(2012) Laurens Kruidenier et al.   NATURE

Effect of the damping function in dispersion corrected density functional theory

(2011) Stefan Grimme et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Use of Solution-Phase Vibrational Frequencies in Continuum Models for the Free Energy of Solvation

(2011) Raphael F. Ribeiro et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MassChroQ: A versatile tool for mass spectrometry quantification

(2011) Benoît Valot et al.   PROTEOMICS

Gabedit-A graphical user interface for computational chemistry softwares

(2010) Abdul-Rahman Allouche   JOURNAL OF COMPUTATIONAL CHEMISTRY

Improved side-chain torsion potentials for the Amber ff99SB protein force field

(2010) Kresten Lindorff-Larsen et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Universal Solvation Model Based on Solute Electron Density and on a Continuum Model of the Solvent Defined by the Bulk Dielectric Constant and Atomic Surface Tensions

(2009) Aleksandr V. Marenich et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Synthesis of [2]- and [3]rotaxanes through Sonogashira coupling

(2009) Jean-Benoît Giguère et al.   TETRAHEDRON LETTERS