How Single Site Mutations Can Help Understanding Structure Formation of Amyloid β1−40

Cryo-EM structures of amyloid-β 42 filaments from human brains

(2022) Yang Yang et al.   SCIENCE

Amyloid β interaction with model cell membranes – What are the toxicity-defining properties of amyloid β?

(2022) Dusan Mrdenovic et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

General Principles Underpinning Amyloid Structure

(2022) Alexander I. P. Taylor et al.   Frontiers in Neuroscience

Non-Proteinogenic Amino Acid β-N-Methylamino-L-Alanine (BMAA): Bioactivity and Ecological Significance

(2022) Olga A. Koksharova et al.   Toxins

Molecular structure of a prevalent amyloid-β fibril polymorph from Alzheimer's disease brain tissue

(2021) Ujjayini Ghosh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-Like Aggregation in Diseases and Biomaterials: Osmosis of Structural Information

(2021) Nicole Balasco et al.   Frontiers in Bioengineering and Biotechnology

SAXS/WAXS Investigation of Amyloid-β(16-22) Peptide Nanotubes

(2021) Theyencheri Narayanan et al.   Frontiers in Bioengineering and Biotechnology

Sensitivity-Enhanced Solid-State NMR Detection of Structural Differences and Unique Polymorphs in Pico- to Nanomolar Amounts of Brain-Derived and Synthetic 42-Residue Amyloid-β Fibrils

(2021) Ayesha Wickramasinghe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revisiting the grammar of Tau aggregation and pathology formation: how new insights from brain pathology are shaping how we study and target Tauopathies

(2021) Galina Limorenko et al.   CHEMICAL SOCIETY REVIEWS

Combination of the Glutaminyl Cyclase Inhibitor PQ912 (Varoglutamstat) and the Murine Monoclonal Antibody PBD-C06 (m6) Shows Additive Effects on Brain Aβ Pathology in Transgenic Mice

(2021) Torsten Hoffmann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Application of the Double-Mutant Cycle Strategy to Protein Aggregation Reveals Transient Interactions in Amyloid-β Oligomers

(2021) Anirban Das et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Amyloid β 42 fibril structure based on small-angle scattering

(2021) Veronica Lattanzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Peptide backbone modifications of amyloid β (1–40) impact fibrillation behavior and neuronal toxicity

(2021) Benedikt Schwarze et al.   Scientific Reports

Probing the Influence of Single-Site Mutations in the Central Cross-β Region of Amyloid β (1–40) Peptides

(2021) Jacob Fritzsch et al.   Biomolecules

Protofibrils of Amyloid-β are Important Targets of a Disease-Modifying Approach for Alzheimer’s Disease

(2020) Kenjiro Ono et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Incorporation of the Nonproteinogenic Amino Acid β-Methylamino-alanine Affects Amyloid β Fibril Properties and Toxicity

(2020) Alexander Korn et al.   ACS Chemical Neuroscience

A Spectroscopic Marker for Structural Transitions Associated with Amyloid-β Aggregation

(2020) Anirban Das et al.   BIOCHEMISTRY

Conformational Characterization of Native and L17A/F19A-Substituted Dutch-Type β-Amyloid Peptides

(2020) Kai-Cyuan He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure and Aggregation Mechanisms in Amyloids

(2020) Zaida L. Almeida et al.   MOLECULES

Complete aggregation pathway of amyloid β (1-40) and (1-42) resolved on an atomically clean interface

(2020) Peter Niraj Nirmalraj et al.   Science Advances

N-Terminal Modified Aβ Variants Enable Modulations to the Structures and Cytotoxicity Levels of Wild-Type Aβ Fibrils through Cross-Seeding

(2020) Zhi-Wen Hu et al.   ACS Chemical Neuroscience

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

(2020) Christine Röder et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage

(2020) Sonia Ciudad et al.   Nature Communications

Lipid-Chaperone Hypothesis: A Common Molecular Mechanism of Membrane Disruption by Intrinsically Disordered Proteins

(2020) Michele F. Sciacca et al.   ACS Chemical Neuroscience

Vibrational Approach to the Dynamics and Structure of Protein Amyloids

(2019) Haoqian Li et al.   MOLECULES

Ordered and Disordered Segments of Amyloid-β Drive Sequential Steps of the Toxic Pathway

(2019) Barun Kumar Maity et al.   ACS Chemical Neuroscience

Molecular structure of an N-terminal phosphorylated β-amyloid fibril

(2019) Zhi-Wen Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Amyloids

(2019) Daniel Otzen et al.   Cold Spring Harbor Perspectives in Biology

Two decades of progress in structural and dynamic studies of amyloids by solid-state NMR

(2019) Christopher P. Jaroniec   JOURNAL OF MAGNETIC RESONANCE

Thermophoretic trap for single amyloid fibril and protein aggregation studies

(2019) Martin Fränzl et al.   NATURE METHODS

Effect of Post-Translational Modifications and Mutations on Amyloid-β Fibrils Dynamics at N-Terminus

(2019) Liliya Vugmeyster et al.   BIOPHYSICAL JOURNAL

The Cyanotoxin and Non-protein Amino Acid β-Methylamino-L-Alanine (L-BMAA) in the Food Chain: Incorporation into Proteins and Its Impact on Human Health

(2019) Rachael A. Dunlop et al.   NEUROTOXICITY RESEARCH

Kinetic Transition in Amyloid Assembly as a Screening Assay for Oligomer-Selective Dyes

(2019) Jeremy Barton et al.   Biomolecules

Cryo-EM of amyloid fibrils and cellular aggregates

(2019) Anthony WP Fitzpatrick et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Synthesis and Aggregation of Polymer‐Amyloid β Conjugates

(2019) Zhanna Evgrafova et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer’s brain tissue

(2019) Marius Kollmer et al.   Nature Communications

Invited Review: The role of prion‐like mechanisms in neurodegenerative diseases

(2019) Z. Jaunmuktane et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Elucidating the Structures of Amyloid Oligomers with Macrocyclic β-Hairpin Peptides: Insights into Alzheimer’s Disease and Other Amyloid Diseases

(2018) Adam G. Kreutzer et al.   ACCOUNTS OF CHEMICAL RESEARCH

Stabilization and characterization of cytotoxic Aβ40 oligomers isolated from an aggregation reaction in the presence of zinc ions

(2018) Benedetta Mannini et al.   ACS Chemical Neuroscience

Amyloid Polymorphism in the Protein Folding and Aggregation Energy Landscape

(2018) Jozef Adamcik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ring structure modifications of phenylalanine 19 increase fibrillation kinetics and reduce toxicity of amyloid β (1–40)

(2018) Alexander Korn et al.   CHEMICAL COMMUNICATIONS

Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies

(2018) Hong Jiang et al.   CHEMICAL REVIEWS

N-Terminal Charged Residues of Amyloid-β Peptide Modulate Amyloidogenesis and Interaction with Lipid Membrane

(2018) Clifford Morris et al.   CHEMISTRY-A EUROPEAN JOURNAL

Protein aggregation in cell biology: An aggregomics perspective of health and disease

(2018) Dezerae Cox et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Origin of metastable oligomers and their effects on amyloid fibril self-assembly

(2018) Filip Hasecke et al.   Chemical Science

Physical basis of amyloid fibril polymorphism

(2018) William Close et al.   Nature Communications

Probing and Trapping a Sensitive Conformation: Amyloid-β Fibrils, Oligomers, and Dimers

(2018) Janelle N. Fawver et al.   JOURNAL OF ALZHEIMERS DISEASE

Glutaminyl Cyclase in Human Cortex: Correlation with (pGlu)-Amyloid-β Load and Cognitive Decline in Alzheimer's Disease

(2018) Markus Morawski et al.   JOURNAL OF ALZHEIMERS DISEASE

Molecular insights into the effect L17A/F19A double mutation on the structure and dynamics of Aβ40 : A molecular dynamics simulation study

(2018) Rajneet Kaur Saini et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Side-chain moieties from the N-terminal region of Aβ are Involved in an oligomer-stabilizing network of interactions

(2018) Kaja Przygońska et al.   PLoS One

Congo Red and amyloids: history and relationship

(2018) Elmira I. Yakupova et al.   BIOSCIENCE REPORTS

Familial Alzheimer's Disease Mutations within the Amyloid Precursor Protein Alter the Aggregation and Conformation of the Amyloid-β Peptide

(2017) Asa Hatami et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spectroscopic Signature for Stable β-Amyloid Fibrils versus β-Sheet-Rich Oligomers

(2017) Justin P. Lomont et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Stereoisomers Probe Steric Zippers in Amyloid-β

(2017) Bappaditya Chandra et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Perturbation of the F19-L34 Contact in Amyloid β (1-40) Fibrils Induces Only Local Structural Changes but Abolishes Cytotoxicity

(2017) Felix Hoffmann et al.   Journal of Physical Chemistry Letters

N-terminal lipid conjugation of amyloid β(1–40) leads to the formation of highly ordered N-terminally extended fibrils

(2017) Juliane Adler et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Fibril structure of amyloid-β(1–42) by cryo–electron microscopy

(2017) Lothar Gremer et al.   SCIENCE

Emerging Structural Understanding of Amyloid Fibrils by Solid-State NMR

(2017) Beat H. Meier et al.   TRENDS IN BIOCHEMICAL SCIENCES

Pre-plaque conformational changes in Alzheimer’s disease-linked Aβ and APP

(2017) O. Klementieva et al.   Nature Communications

Cellular Regulation of Amyloid Formation in Aging and Disease

(2017) Esther Stroo et al.   Frontiers in Neuroscience

Enhanced Fibril Fragmentation of N-Terminally Truncated and Pyroglutamyl-Modified Aβ Peptides

(2016) Melanie Wulff et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Solid-state NMR sequential assignment of an Amyloid-β(1–42) fibril polymorph

(2016) Francesco Ravotti et al.   Biomolecular NMR Assignments

A Detailed Analysis of the Morphology of Fibrils of Selectively Mutated Amyloid β (1-40)

(2016) Juliane Adler et al.   CHEMPHYSCHEM

Membrane Damage Induced by Amyloid Beta and a Potential Link with Neuroinflammation

(2016) Eduardo J. Fernandez-Perez et al.   CURRENT PHARMACEUTICAL DESIGN

X-ray Crystallographic Structure of Oligomers Formed by a Toxic β-Hairpin Derived from α-Synuclein: Trimers and Higher-Order Oligomers

(2016) Patrick J. Salveson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atomic-resolution structure of a disease-relevant Aβ(1–42) amyloid fibril

(2016) Marielle Aulikki Wälti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation modifies the molecular stability of β-amyloid deposits

(2016) Nasrollah Rezaei-Ghaleh et al.   Nature Communications

Solid-state NMR structure of a pathogenic fibril of full-length human α-synuclein

(2016) Marcus D Tuttle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

β-methylamino-L-alanine (BMAA) is not found in the brains of patients with confirmed Alzheimer’s disease

(2016) Julie P. Meneely et al.   Scientific Reports

Molecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic Resonance

(2016) Robert Tycko   Cold Spring Harbor Perspectives in Medicine

Combined Solution- and Magic Angle Spinning NMR Reveals Regions of Distinct Dynamics in Amyloid β Protofibrils

(2016) Christofer Lendel et al.   ChemistrySelect

L17A/F19A Substitutions Augment the α-Helicity of β-Amyloid Peptide Discordant Segment

(2016) Chu-Ting Liang et al.   PLoS One

Fibrils of Truncated Pyroglutamyl-Modified Aβ Peptide Exhibit a Similar Structure as Wildtype Mature Aβ Fibrils

(2016) Holger A. Scheidt et al.   Scientific Reports

An Early Folding Contact between Phe19 and Leu34 is Critical for Amyloid-β Oligomer Toxicity

(2015) Anand K. Das et al.   ACS Chemical Neuroscience

Hydrogen/Deuterium Exchange and Molecular Dynamics Analysis of Amyloid Fibrils Formed by a D69K Charge-Pair Mutant of Human Apolipoprotein C-II

(2015) Yu Mao et al.   BIOCHEMISTRY

Charge and Charge-Pair Mutations Alter the Rate of Assembly and Structural Properties of Apolipoprotein C-II Amyloid Fibrils

(2015) Yu Mao et al.   BIOCHEMISTRY

Alzheimer’s Protective A2T Mutation Changes the Conformational Landscape of the Aβ1–42 Monomer Differently Than Does the A2V Mutation

(2015) Payel Das et al.   BIOPHYSICAL JOURNAL

The route to protein aggregate superstructures: Particulates and amyloid-like spherulites

(2015) Valeria Vetri et al.   FEBS LETTERS

Steric Crowding of the Turn Region Alters the Tertiary Fold of Amyloid-β18–35and Makes It Soluble

(2015) Muralidharan Chandrakesan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid-β Peptide Aβ3pE-42 Induces Lipid Peroxidation, Membrane Permeabilization, and Calcium Influx in Neurons

(2015) Adam P. Gunn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Surviving protein quality control catastrophes - from cells to organisms

(2015) K. Schneider et al.   JOURNAL OF CELL SCIENCE

Successive Stages of Amyloid-β Self-Assembly Characterized by Solid-State Nuclear Magnetic Resonance with Dynamic Nuclear Polarization

(2015) Alexey Potapov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High Resolution Structural Characterization of Aβ42 Amyloid Fibrils by Magic Angle Spinning NMR

(2015) Michael T. Colvin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of amyloid formation revealed by solution NMR

(2015) Theodoros K. Karamanos et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

The path of no return-Truncated protein N-termini and current ignorance of their genesis

(2015) Nikolaus Fortelny et al.   PROTEOMICS

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Golgi fragmentation in Alzheimer's disease

(2015) Gunjan Joshi et al.   Frontiers in Neuroscience

Significant Structural Differences between Transient Amyloid-β Oligomers and Less-Toxic Fibrils in Regions Known To Harbor Familial Alzheimer′s Mutations

(2014) Bidyut Sarkar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils

(2014) Christofer Lendel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Molecular Mechanisms of Alzheimer Disease Protection by the A673T Allele of Amyloid Precursor Protein

(2014) Janice A. Maloney et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Alzheimer Disease Protective Mutation A2T Modulates Kinetic and Thermodynamic Properties of Amyloid-β (Aβ) Aggregation

(2014) Iryna Benilova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyroglutamylated Amyloid-β Peptide Reverses Cross β-Sheets by a Prion-Like Mechanism

(2014) Jason O. Matos et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Turn Plasticity Distinguishes Different Modes of Amyloid-β Aggregation

(2014) Nasrollah Rezaei-Ghaleh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid, Cell-Free Assay for Membrane-Active Forms of Amyloid-β

(2014) Debanjan Bhowmik et al.   LANGMUIR

Characterization of biometal profiles in neurological disorders

(2014) Stefanie Pfaender et al.   Metallomics

Local interactions influence the fibrillation kinetics, structure and dynamics of Aβ(1–40) but leave the general fibril structure unchanged

(2014) Juliane Adler et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Truncated and modified amyloid-beta species

(2014) Markus P Kummer et al.   Alzheimers Research & Therapy

Molecular Structures of Amyloid and Prion Fibrils: Consensus versus Controversy

(2013) Robert Tycko et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular Structure of β-Amyloid Fibrils in Alzheimer’s Disease Brain Tissue

(2013) Jun-Xia Lu et al.   CELL

Biophysical Studies of the Amyloid β-Peptide: Interactions with Metal Ions and Small Molecules

(2013) Sebastian Wärmländer et al.   CHEMBIOCHEM

The basic structural motif and major biophysical properties of Amyloid-β are encoded in the fragment 18–35

(2013) Muralidharan Chandrakesan et al.   CHEMICAL PHYSICS

The benzazole scaffold: a SWAT to combat Alzheimer's disease

(2013) Sabrina Noël et al.   CHEMICAL SOCIETY REVIEWS

Role of Metal Ions in the Self-assembly of the Alzheimer’s Amyloid-β Peptide

(2013) Peter Faller et al.   INORGANIC CHEMISTRY

The role of amyloidogenic protein oligomerization in neurodegenerative disease

(2013) Gregor P. Lotz et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The Non-Protein Amino Acid BMAA Is Misincorporated into Human Proteins in Place of l-Serine Causing Protein Misfolding and Aggregation

(2013) Rachael Anne Dunlop et al.   PLoS One

A Structure-Toxicity Study of Aß42 Reveals a New Anti-Parallel Aggregation Pathway

(2013) Hélène Vignaud et al.   PLoS One

Atomic structure and hierarchical assembly of a cross-  amyloid fibril

(2013) A. W. P. Fitzpatrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

What does make an amyloid toxic: Morphology, structure or interaction with membrane?

(2012) Karine Berthelot et al.   BIOCHIMIE

Altering Peptide Fibrillization by Polymer Conjugation

(2012) Sabrina Dehn et al.   BIOMACROMOLECULES

Bioinorganic Chemistry of Alzheimer’s Disease

(2012) Kasper P. Kepp   CHEMICAL REVIEWS

Breaking the amyloidogenicity code: Methods to predict amyloids from amino acid sequence

(2012) Abdullah B. Ahmed et al.   FEBS LETTERS

Solid-state NMR Reveals a Close Structural Relationship between Amyloid-β Protofibrils and Oligomers

(2012) Holger A. Scheidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Regulation of Amyloid-β Endocytic Trafficking and Lysosomal Degradation by Apolipoprotein E Isoforms

(2012) Jie Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fiber Diffraction Data Indicate a Hollow Core for the Alzheimer's Aβ 3-Fold Symmetric Fibril

(2012) Michele McDonald et al.   JOURNAL OF MOLECULAR BIOLOGY

N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation

(2012) Dagmar Schlenzig et al.   JOURNAL OF NEUROCHEMISTRY

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

(2012) Thorlakur Jonsson et al.   NATURE

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Antiparallel  -sheet architecture in Iowa-mutant  -amyloid fibrils

(2012) W. Qiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Good gene, bad gene: New APP variant may be both

(2012) Giuseppe Di Fede et al.   PROGRESS IN NEUROBIOLOGY

Solid-State NMR Spectroscopic Investigation of Aβ Protofibrils: Implication of a β-Sheet Remodeling upon Maturation into Terminal Amyloid Fibrils

(2011) Holger A. Scheidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aβ40(L17A/F19A) mutant diminishes the aggregation and neurotoxicity of Aβ40

(2011) Yi-Ru Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A method for probing the mutational landscape of amyloid structure

(2011) Charles W. O'Donnell et al.   BIOINFORMATICS

Zn++ Binding Disrupts the Asp23-Lys28 Salt Bridge without Altering the Hairpin-Shaped Cross-β Structure of Aβ42 Amyloid Aggregates

(2011) Venus Singh Mithu et al.   BIOPHYSICAL JOURNAL

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease

(2011) Sathish Kumar et al.   EMBO JOURNAL

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: Characterizing a new regulatory motif

(2011) Bryan Maloney et al.   GENE

Dynamics of Amyloid β Fibrils Revealed by Solid-state NMR

(2011) Holger A. Scheidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular-Level Examination of Cu2+Binding Structure for Amyloid Fibrils of 40-Residue Alzheimer’s β by Solid-State NMR Spectroscopy

(2011) Sudhakar Parthasarathy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Structural Model of Aβ40Fibrils

(2011) Ivano Bertini et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Diversity of Assembly Mechanisms of a Generic Amyloid Fold

(2011) Timo Eichner et al.   MOLECULAR CELL

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Nitration of Tyrosine 10 Critically Enhances Amyloid β Aggregation and Plaque Formation

(2011) Markus P. Kummer et al.   NEURON

Polymorphic Structures of Alzheimer's β-Amyloid Globulomers

(2011) Xiang Yu et al.   PLoS One

Neuropathology of the recessive A673V APP mutation: Alzheimer disease with distinctive features

(2010) Giorgio Giaccone et al.   ACTA NEUROPATHOLOGICA

Molecular mechanism of Thioflavin-T binding to amyloid fibrils

(2010) Matthew Biancalana et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

CD measurements of β-amyloid (1-40) and (1-42) in the condensed phase

(2010) Takunori Harada et al.   BIOPOLYMERS

Transformation of amyloid β(1–40) oligomers into fibrils is characterized by a major change in secondary structure

(2010) Rabia Sarroukh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Aβ(1–40) Forms Five Distinct Amyloid Structures whose β-Sheet Contents and Fibril Stabilities Are Correlated

(2010) Ravindra Kodali et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Variations in the Cross-β Core of Amyloid β Fibrils Revealed by Deep UV Resonance Raman Spectroscopy

(2010) Ludmila A. Popova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembly of PEGylated Peptide Conjugates Containing a Modified Amyloid β-Peptide Fragment

(2010) V. Castelletto et al.   LANGMUIR

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fibril fragmentation in amyloid assembly and cytotoxicity

(2010) Wei-Feng Xue et al.   Prion

Stabilization of neurotoxic Alzheimer amyloid-  oligomers by protein engineering

(2010) A. Sandberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neighbor-Dependent Ramachandran Probability Distributions of Amino Acids Developed from a Hierarchical Dirichlet Process Model

(2010) Daniel Ting et al.   PLoS Computational Biology

Cyanobacterial neurotoxin BMAA in ALS and Alzheimer’s disease

(2009) J. Pablo et al.   ACTA NEUROLOGICA SCANDINAVICA

Identification of Aspartic and Isoaspartic Acid Residues in Amyloid β Peptides, Including Aβ1−42, Using Electron−Ion Reactions

(2009) Nadezda P. Sargaeva et al.   ANALYTICAL CHEMISTRY

Protein aggregation: more than just fibrils

(2009) Mark R.H. Krebs et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Copper Enhances Amyloid-β Peptide Neurotoxicity and non β-Aggregation: A Series of Experiments Conducted upon Copper-Bound and Copper-Free Amyloid-β Peptide

(2009) Xueling Dai et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

An Analytical Solution to the Kinetics of Breakable Filament Assembly

(2009) T. P. J. Knowles et al.   SCIENCE

Aggregation structure of Alzheimer amyloid-β(1–40) peptide with sodium dodecyl sulfate as revealed by small-angle X-ray and neutron scattering

(2009) Jhih-Min Lin et al.   Soft Matter

BETASCAN: Probable β-amyloids Identified by Pairwise Probabilistic Analysis

(2009) Allen W. Bryan et al.   PLoS Computational Biology

Membrane binding of lipidated Ras peptides and proteins — The structural point of view

(2008) Luc Brunsveld et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of PEG Crystallization on the Self-Assembly of PEG/Peptide Copolymers Containing Amyloid Peptide Fragments

(2008) Ian W. Hamley et al.   LANGMUIR

Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

(2008) Stephan Schilling et al.   NATURE MEDICINE

Extrinsic Fluorescent Dyes as Tools for Protein Characterization

(2008) Andrea Hawe et al.   PHARMACEUTICAL RESEARCH

Stabilization of a β-hairpin in monomeric Alzheimer's amyloid-β peptide inhibits amyloid formation

(2008) Wolfgang Hoyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular structural basis for polymorphism in Alzheimer's  -amyloid fibrils

(2008) A. K. Paravastu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA