Activatable Raman Probes Utilizing Enzyme-Induced Aggregate Formation for Selective Ex Vivo Imaging

Live-Cell Fluorescence Lifetime Multiplexing Using Synthetic Fluorescent Probes

(2022) Michelle S. Frei et al.   ACS Chemical Biology

Super-multiplexed vibrational probes: Being colorful makes a difference

(2022) Naixin Qian et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Bringing Vibrational Imaging to Chemical Biology with Molecular Probes

(2022) Jiajun Du et al.   ACS Chemical Biology

Raman Spectroscopy for Chemical Biology Research

(2022) Kosuke Dodo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Frequency Changes in Terminal Alkynes Provide Strong, Sensitive, and Solvatochromic Raman Probes of Biochemical Environments

(2022) Matthew G. Romei et al.   Journal of Physical Chemistry B

Ultra-bright Raman dots for multiplexed optical imaging

(2021) Zhilun Zhao et al.   Nature Communications

9-Cyanopyronin probe palette for super-multiplexed vibrational imaging

(2021) Yupeng Miao et al.   Nature Communications

Switchable stimulated Raman scattering microscopy with photochromic vibrational probes

(2021) Jianpeng Ao et al.   Nature Communications

Super-multiplex imaging of cellular dynamics and heterogeneity by integrated stimulated Raman and fluorescence microscopy

(2021) Jingwen Shou et al.   iScience

Multicolor Photoactivatable Raman Probes for Subcellular Imaging and Tracking by Cyclopropenone Caging

(2021) Jiajun Du et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters

(2021) Lei Dong et al.   Chemical Science

Activatable Formation of Emissive Excimers for Highly Selective Detection of β-Galactosidase

(2020) Yang Li et al.   ANALYTICAL CHEMISTRY

An Activatable AIEgen Probe for High‐Fidelity Monitoring of Overexpressed Tumor Enzyme Activity and Its Application to Surgical Tumor Excision

(2020) Haidong Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicolor Activatable Raman Probes for Simultaneous Detection of Plural Enzyme Activities

(2020) Hiroyoshi Fujioka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Red Fluorescence Probe Targeted to Dipeptidylpeptidase-IV for Highly Sensitive Detection of Esophageal Cancer

(2019) Akira Ogasawara et al.   BIOCONJUGATE CHEMISTRY

Near-Infrared Aggregation-Induced Emission-Active Probe Enables in situ and Long-Term Tracking of Endogenous β-Galactosidase Activity

(2019) Wei Fu et al.   Frontiers in Chemistry

Biological imaging of chemical bonds by stimulated Raman scattering microscopy

(2019) Fanghao Hu et al.   NATURE METHODS

Optical mapping of biological water in single live cells by stimulated Raman excited fluorescence microscopy

(2019) Lixue Shi et al.   Nature Communications

Electronic Pre-resonance Stimulated Raman Scattering Microscopy

(2018) Lu Wei et al.   Journal of Physical Chemistry Letters

A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering

(2018) Chen Zeng et al.   ANALYST

Multicolor Stimulated Raman Scattering Microscopy With Fast Wavelength-Tunable Yb Fiber Laser

(2018) Yasuyuki Ozeki et al.   IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS

Super-multiplex vibrational imaging

(2017) Lu Wei et al.   NATURE

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Hyperspectral phasor analysis enables multiplexed 5D in vivo imaging

(2017) Francesco Cutrale et al.   NATURE METHODS

Threshold concentration in the nonlinear absorbance law

(2017) Alexander Yu. Tolbin et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Detection of LacZ -Positive Cells in Living Tissue with Single-Cell Resolution

(2016) Tomohiro Doura et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Rhodamine-Based Fluorescent Probe for Multicolour In Vivo Imaging

(2016) Ryu J. Iwatate et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multi-target spectrally resolved fluorescence lifetime imaging microscopy

(2016) Thomas Niehörster et al.   NATURE METHODS

Why measure enzyme activities in the era of systems biology?

(2013) Mark Stitt et al.   TRENDS IN PLANT SCIENCE

Alkyne-Tag Raman Imaging for Visualization of Mobile Small Molecules in Live Cells

(2012) Hiroyuki Yamakoshi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-speed molecular spectral imaging of tissue with stimulated Raman scattering

(2012) Yasuyuki Ozeki et al.   Nature Photonics

The molecular aggregation of pyronin Y in natural bentonite clay suspension

(2011) Kadem Meral et al.   JOURNAL OF LUMINESCENCE

β-Galactosidase Fluorescence Probe with Improved Cellular Accumulation Based on a Spirocyclized Rhodol Scaffold

(2011) Mako Kamiya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid Cancer Detection by Topically Spraying a  -Glutamyltranspeptidase-Activated Fluorescent Probe

(2011) Y. Urano et al.   Science Translational Medicine

Effect of surfactants on the aggregation of pyronin B and pyronin Y in aqueous solution

(2009) Mustafa Arık et al.   JOURNAL OF LUMINESCENCE

Vibrational imaging based on stimulated Raman scattering microscopy

(2009) P Nandakumar et al.   NEW JOURNAL OF PHYSICS

Analysis and experimental assessment of the sensitivity of stimulated Raman scattering microscopy

(2009) Yasuyuki Ozeki et al.   OPTICS EXPRESS

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

(2008) Christian W. Freudiger et al.   SCIENCE