Biological imaging of chemical bonds by stimulated Raman scattering microscopy

High-throughput label-free molecular fingerprinting flow cytometry

(2019) Kotaro Hiramatsu et al.   Science Advances

Saturated Stimulated-Raman-Scattering Microscopy for Far-Field Superresolution Vibrational Imaging

(2019) Li Gong et al.   Physical Review Applied

Phenazine production promotes antibiotic tolerance and metabolic heterogeneity in Pseudomonas aeruginosa biofilms

(2019) Konstanze T. Schiessl et al.   Nature Communications

Volumetric chemical imaging by clearing-enhanced stimulated Raman scattering microscopy

(2019) Mian Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death

(2019) Javier Garcia-Bermudez et al.   NATURE

Raman Imaging of Small Biomolecules

(2019) Yihui Shen et al.   Annual Review of Biophysics

Multicolor Raman Beads for Multiplexed Tumor Cell and Tissue Imaging and in Vivo Tumor Spectral Detection

(2019) QingQing Jin et al.   ANALYTICAL CHEMISTRY

Stimulated Raman excited fluorescence spectroscopy and imaging

(2019) Hanqing Xiong et al.   Nature Photonics

Spectral tracing of deuterium for imaging glucose metabolism

(2019) Luyuan Zhang et al.   Nature Biomedical Engineering

Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering

(2019) Yuta Suzuki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis

(2018) Michael M. Gaschler et al.   ACS Chemical Biology

Two-color vibrational imaging of glucose metabolism using stimulated Raman scattering

(2018) Rong Long et al.   CHEMICAL COMMUNICATIONS

Fingerprint Stimulated Raman Scattering Imaging Reveals Retinoid Coupling Lipid Metabolism and Survival

(2018) Andy Jing Chen et al.   CHEMPHYSCHEM

In situ chemically specific mapping of agrochemical seed coatings using stimulated Raman scattering microscopy

(2018) Chun-Chin Wang et al.   Journal of Biophotonics

Supermultiplexed optical imaging and barcoding with engineered polyynes

(2018) Fanghao Hu et al.   NATURE METHODS

A ratiometric Raman probe for live-cell imaging of hydrogen sulfide in mitochondria by stimulated Raman scattering

(2018) Chen Zeng et al.   ANALYST

Small Unnatural Amino Acid Carried Raman Tag for Molecular Imaging of Genetically Targeted Proteins

(2018) Jing Zhang et al.   Journal of Physical Chemistry Letters

In Situ Stimulated Raman Scattering (SRS) Microscopy Study of the Dissolution of Sustained-Release Implant Formulation

(2018) Andrew T. Francis et al.   MOLECULAR PHARMACEUTICS

Detecting stimulated Raman responses of molecules in plasmonic gap using photon induced forces

(2018) Venkata Ananth Tamma et al.   OPTICS EXPRESS

Broadband hyperspectral stimulated Raman scattering microscopy with a parabolic fiber amplifier source

(2018) Benjamin Figueroa et al.   Biomedical Optics Express

Label-free imaging of amyloid plaques in Alzheimer’s disease with stimulated Raman scattering microscopy

(2018) Minbiao Ji et al.   Science Advances

Selective Suppression of Stimulated Raman Scattering with Another Competing Stimulated Raman Scattering

(2017) Doyeon Kim et al.   Journal of Physical Chemistry Letters

Label-Free Vibrational Spectroscopic Imaging of Neuronal Membrane Potential

(2017) Hyeon Jeong Lee et al.   Journal of Physical Chemistry Letters

Super-multiplex vibrational imaging

(2017) Lu Wei et al.   NATURE

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

Stimulated Raman scattering microscopy and spectroscopy with a rapid scanning optical delay line

(2017) Ruoyu He et al.   OPTICS LETTERS

High-speed stimulated hyperspectral Raman imaging using rapid acousto-optic delay lines

(2017) Mohammed S. Alshaykh et al.   OPTICS LETTERS

Metabolic activity induces membrane phase separation in endoplasmic reticulum

(2017) Yihui Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging drug uptake by bioorthogonal stimulated Raman scattering microscopy

(2017) William J. Tipping et al.   Chemical Science

In Vivo and in Situ Spectroscopic Imaging by a Handheld Stimulated Raman Scattering Microscope

(2017) Chien-Sheng Liao et al.   ACS Photonics

Stimulated Raman scattering spectroscopic optical coherence tomography

(2017) Francisco E. Robles et al.   Optica

Stimulated Raman scattering flow cytometry for label-free single-particle analysis

(2017) Chi Zhang et al.   Optica

Rapid intraoperative histology of unprocessed surgical specimens via fibre-laser-based stimulated Raman scattering microscopy

(2017) Daniel A. Orringer et al.   Nature Biomedical Engineering

Live-Cell Bioorthogonal Chemical Imaging: Stimulated Raman Scattering Microscopy of Vibrational Probes

(2016) Lu Wei et al.   ACCOUNTS OF CHEMICAL RESEARCH

Hepatitis C Virus Selectively Alters the Intracellular Localization of Desmosterol

(2016) Valerie A. Villareal et al.   ACS Chemical Biology

Stimulated Raman Scattering: From Bulk to Nano

(2016) Richard C. Prince et al.   CHEMICAL REVIEWS

Stimulated Raman scattering microscopy: an emerging tool for drug discovery

(2016) W. J. Tipping et al.   CHEMICAL SOCIETY REVIEWS

Label-free Imaging of Neurotransmitter Acetylcholine at Neuromuscular Junctions with Stimulated Raman Scattering

(2016) Dan Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Broadband stimulated Raman scattering spectroscopy by a photonic time stretcher

(2016) Francesco Saltarelli et al.   OPTICS EXPRESS

Stimulated Raman spectroscopic imaging by microsecond delay-line tuning

(2016) Chien-Sheng Liao et al.   Optica

Dual-phase stimulated Raman scattering microscopy for real-time two-color imaging

(2016) Ruoyu He et al.   Optica

Probing the metabolic heterogeneity of live Euglena gracilis with stimulated Raman scattering microscopy

(2016) Yoshifumi Wakisaka et al.   Nature Microbiology

Depth-resolved mid-infrared photothermal imaging of living cells and organisms with submicrometer spatial resolution

(2016) D. Zhang et al.   Science Advances

Imaging Complex Protein Metabolism in Live Organisms by Stimulated Raman Scattering Microscopy with Isotope Labeling

(2015) Lu Wei et al.   ACS Chemical Biology

Vibrational Imaging of Glucose Uptake Activity in Live Cells and Tissues by Stimulated Raman Scattering

(2015) Fanghao Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage

(2015) Alba Alfonso-García et al.   JOURNAL OF BIOMEDICAL OPTICS

Chemically sensitive bioimaging with coherent Raman scattering

(2015) Charles H. Camp Jr et al.   Nature Photonics

Suppression of stimulated Raman scattering by an electromagnetically-induced-transparency–like scheme and its application for super-resolution microscopy

(2015) Li Gong et al.   PHYSICAL REVIEW A

Molecular diffusion in the human nail measured by stimulated Raman scattering microscopy

(2015) Wing Sin Chiu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Label-free DNA imaging in vivo with stimulated Raman scattering microscopy

(2015) Fa-Ke Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine

(2015) J.-X. Cheng et al.   SCIENCE

Detection of human brain tumor infiltration with quantitative stimulated Raman scattering microscopy

(2015) Minbiao Ji et al.   Science Translational Medicine

Toward Label-Free Super-Resolution Microscopy

(2015) W. Ruchira Silva et al.   ACS Photonics

Spectrometer-free vibrational imaging by retrieving stimulated Raman signal from highly scattered photons

(2015) C.-S. Liao et al.   Science Advances

Live-cell vibrational imaging of choline metabolites by stimulated Raman scattering coupled with isotope-based metabolic labeling

(2014) Fanghao Hu et al.   ANALYST

Live-Cell Quantitative Imaging of Proteome Degradation by Stimulated Raman Scattering

(2014) Yihui Shen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Live-Cell Stimulated Raman Scattering Imaging of Alkyne-Tagged Biomolecules

(2014) Senlian Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

(2014) Shuhua Yue et al.   Cell Metabolism

In Vivo Metabolic Fingerprinting of Neutral Lipids with Hyperspectral Stimulated Raman Scattering Microscopy

(2014) Dan Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolor Live-Cell Chemical Imaging by Isotopically Edited Alkyne Vibrational Palette

(2014) Zhixing Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging the intracellular distribution of tyrosine kinase inhibitors in living cells with quantitative hyperspectral stimulated Raman scattering

(2014) Dan Fu et al.   Nature Chemistry

Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering

(2014) Lu Wei et al.   NATURE METHODS

Seeing a single molecule vibrate through time-resolved coherent anti-Stokes Raman scattering

(2014) Steven Yampolsky et al.   Nature Photonics

Stimulated Raman scattering microscopy with a robust fibre laser source

(2014) Christian W. Freudiger et al.   Nature Photonics

Breaking the diffraction limit by saturation in stimulated-Raman-scattering microscopy: A theoretical study

(2014) Li Gong et al.   PHYSICAL REVIEW A

Label-free Chemically Specific Imaging in Planta with Stimulated Raman Scattering Microscopy

(2013) Jessica C. Mansfield et al.   ANALYTICAL CHEMISTRY

Label-Free Quantitative Imaging of Cholesterol in Intact Tissues by Hyperspectral Stimulated Raman Scattering Microscopy

(2013) Ping Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical reporters for biological discovery

(2013) Markus Grammel et al.   Nature Chemical Biology

Near shot-noise limited hyperspectral stimulated Raman scattering spectroscopy using low energy lasers and a fast CMOS array

(2013) William Rock et al.   OPTICS EXPRESS

Multicolor stimulated Raman scattering microscopy with a rapidly tunable optical parametric oscillator

(2013) Lingjie Kong et al.   OPTICS LETTERS

Vibrational imaging of newly synthesized proteins in live cells by stimulated Raman scattering microscopy

(2013) L. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a multiplex stimulated Raman microscope for spectral imaging through multi-channel lock-in detection

(2013) Keisuke Seto et al.   REVIEW OF SCIENTIFIC INSTRUMENTS

Quantitative Vibrational Imaging by Hyperspectral Stimulated Raman Scattering Microscopy and Multivariate Curve Resolution Analysis

(2012) Delong Zhang et al.   ANALYTICAL CHEMISTRY

Characterization of Cholesterol Crystals in Atherosclerotic Plaques Using Stimulated Raman Scattering and Second-Harmonic Generation Microscopy

(2012) Jeffrey L. Suhalim et al.   BIOPHYSICAL JOURNAL

Hyperspectral Imaging with Stimulated Raman Scattering by Chirped Femtosecond Lasers

(2012) Dan Fu et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Quantitative Chemical Imaging with Multiplex Stimulated Raman Scattering Microscopy

(2012) Dan Fu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Alkyne-Tag Raman Imaging for Visualization of Mobile Small Molecules in Live Cells

(2012) Hiroyuki Yamakoshi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multicolored stain-free histopathology with coherent Raman imaging

(2012) Christian W Freudiger et al.   LABORATORY INVESTIGATION

Multicolor stimulated Raman scattering microscopy

(2012) Fa-Ke Lu et al.   MOLECULAR PHYSICS

High-speed molecular spectral imaging of tissue with stimulated Raman scattering

(2012) Yasuyuki Ozeki et al.   Nature Photonics

Small molecule perimeter defense in entomopathogenic bacteria

(2012) J. M. Crawford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Does Plant Cell Wall Nanoscale Architecture Correlate with Enzymatic Digestibility?

(2012) S.-Y. Ding et al.   SCIENCE

Coherent Nonlinear Optical Imaging: Beyond Fluorescence Microscopy

(2011) Wei Min et al.   Annual Review of Physical Chemistry

Surface-Enhanced Femtosecond Stimulated Raman Spectroscopy

(2011) Renee R. Frontiera et al.   Journal of Physical Chemistry Letters

Highly Sensitive Vibrational Imaging by Femtosecond Pulse Stimulated Raman Loss

(2011) Delong Zhang et al.   Journal of Physical Chemistry Letters

Imaging of EdU, an Alkyne-Tagged Cell Proliferation Probe, by Raman Microscopy

(2011) Hiroyuki Yamakoshi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging Drug Delivery to Skin with Stimulated Raman Scattering Microscopy

(2011) Brian G. Saar et al.   MOLECULAR PHARMACEUTICS

RNAi screening for fat regulatory genes with SRS microscopy

(2011) Meng C Wang et al.   NATURE METHODS

Highly specific label-free molecular imaging with spectrally tailored excitation-stimulated Raman scattering (STE-SRS) microscopy

(2011) Christian W. Freudiger et al.   Nature Photonics

Stimulated Raman scattering microscopy by spectral focusing and fiber-generated soliton as Stokes pulse

(2011) Esben Ravn Andresen et al.   OPTICS LETTERS

Vibrational imaging of tablets by epi-detected stimulated Raman scattering microscopy

(2010) Mikhail N. Slipchenko et al.   ANALYST

Label-Free, Real-Time Monitoring of Biomass Processing with Stimulated Raman Scattering Microscopy

(2010) Brian G. Saar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Video-Rate Molecular Imaging in Vivo with Stimulated Raman Scattering

(2010) B. G. Saar et al.   SCIENCE

Room-Temperature Detection of a Single Molecule's Absorption by Photothermal Contrast

(2010) A. Gaiduk et al.   SCIENCE

Vibrational imaging based on stimulated Raman scattering microscopy

(2009) P Nandakumar et al.   NEW JOURNAL OF PHYSICS

Analysis and experimental assessment of the sensitivity of stimulated Raman scattering microscopy

(2009) Yasuyuki Ozeki et al.   OPTICS EXPRESS

Label-Free Biomedical Imaging with High Sensitivity by Stimulated Raman Scattering Microscopy

(2008) Christian W. Freudiger et al.   SCIENCE