Supersaturating lipid-based solid dispersion of atazanavir provides enhanced solubilization and supersaturation in the digestive aqueous phase

Supersaturable self-emulsifying drug delivery system: A strategy for improving the loading and oral bioavailability of quercetin

(2022) Arvind Sirvi et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Hydroxypropyl methylcellulose acetate succinate as an exceptional polymer for amorphous solid dispersion formulations: A review from bench to clinic

(2022) Arun Butreddy   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Biorelevant dissolution testing and physiologically based absorption modeling to predict in vivo performance of supersaturating drug delivery systems

(2021) Samarth D Thakore et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Supersaturated lipid-based drug delivery systems – exploring impact of lipid composition type and drug properties on supersaturability and physical stability

(2020) Alexandra-Roxana Ilie et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

The Effect of Medium Chain and Long Chain Triglycerides Incorporated in Self-Nano Emulsifying Drug Delivery Systems on Oral Absorption of Cannabinoids in Rats

(2020) Dvora Izgelov et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Quantifying In Vivo Luminal Drug Solubilization -Supersaturation-Precipitation Profiles to Explain the Performance of Lipid Based Formulations

(2020) Yusuke Tanaka et al.   PHARMACEUTICAL RESEARCH

Atazanavir, alone or in combination with ritonavir, inhibits SARS-CoV-2 replication and pro-inflammatory cytokine production

(2020) Natalia Fintelman-Rodrigues et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax

(2020) Niklas J. Koehl et al.   Pharmaceutics

Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across PermeapadⓇ membrane and in vivo absorption

(2020) Alexandra-Roxana Ilie et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Applying Computational Predictions of Biorelevant Solubility Ratio Upon Self-Emulsifying Lipid-Based Formulations Dispersion to Predict Dose Number

(2020) Harriet Bennett-Lenane et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Influence of Solidification on the in vitro Solubilisation of Blonanserin Loaded Supersaturated Lipid-Based Oral Formulations

(2020) Amalie Møller et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Supersaturated silica-lipid hybrids (super-SLH): An improved solid-state lipid-based oral drug delivery system with enhanced drug loading

(2018) Hayley B. Schultz et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Montmorillonite and Laponite Clay Materials for the Solidification of Lipid-Based Formulations for the Basic Drug Blonanserin: In Vitro and in Vivo Investigations

(2018) Tahnee J. Dening et al.   MOLECULAR PHARMACEUTICS

Solidification to improve the biopharmaceutical performance of SEDDS: Opportunities and challenges

(2018) Paul Joyce et al.   ADVANCED DRUG DELIVERY REVIEWS

Supersaturated silica-lipid hybrid (super-SLH) oral drug delivery systems: Balancing drug loading and in vivo performance

(2018) Hayley B Schultz et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery

(2017) Michael Morgen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Montmorillonite-lipid hybrid carriers for ionizable and neutral poorly water-soluble drugs: Formulation, characterization and in vitro lipolysis studies

(2017) Tahnee J. Dening et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Comparison across Three Hybrid Lipid-Based Drug Delivery Systems for Improving the Oral Absorption of the Poorly Water-Soluble Weak Base Cinnarizine

(2017) Paul Joyce et al.   MOLECULAR PHARMACEUTICS

Transient Supersaturation Supports Drug Absorption from Lipid-Based Formulations for Short Periods of Time, but Ongoing Solubilization Is Required for Longer Absorption Periods

(2017) Matthew F. Crum et al.   MOLECULAR PHARMACEUTICS

Nanostructured Montmorillonite Clay for Controlling the Lipase-Mediated Digestion of Medium Chain Triglycerides

(2016) Tahnee J. Dening et al.   ACS Applied Materials & Interfaces

Enhanced oral delivery of celecoxib via the development of a supersaturable amorphous formulation utilising mesoporous silica and co-loaded HPMCAS

(2016) A.-L. Lainé et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Novel Nanostructured Solid Materials for Modulating Oral Drug Delivery from Solid-State Lipid-Based Drug Delivery Systems

(2015) Tahnee J. Dening et al.   AAPS Journal

Advances and challenges in PBPK modeling – Analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base

(2015) Mark Berlin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

pH-Dependent Liquid–Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs

(2015) Anura S. Indulkar et al.   MOLECULAR PHARMACEUTICS

Pluronic-Functionalized Silica–Lipid Hybrid Microparticles: Improving the Oral Delivery of Poorly Water-Soluble Weak Bases

(2015) Shasha Rao et al.   MOLECULAR PHARMACEUTICS

In Vitro Lipolysis Data Does Not Adequately Predict the In Vivo Performance of Lipid-Based Drug Delivery Systems Containing Fenofibrate

(2014) Nicky Thomas et al.   AAPS Journal

Lipid-Based Formulations Solidified Via Adsorption onto the Mesoporous Carrier Neusilin® US2: Effect of Drug Type and Formulation Composition on In Vitro Pharmaceutical Performance

(2014) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Role of Porous Nanostructure in Controlling Lipase-Mediated Digestion of Lipid Loaded into Silica Particles

(2014) Paul Joyce et al.   LANGMUIR

In Vitro and In Situ Evaluation of pH-Dependence of Atazanavir Intestinal Permeability and Interactions with Acid-Reducing Agents

(2014) Olena Kis et al.   PHARMACEUTICAL RESEARCH

Enhanced dissolution of celecoxib by supersaturating self-emulsifying drug delivery system (S-SEDDS) formulation

(2013) Woo Heon Song et al.   ARCHIVES OF PHARMACAL RESEARCH

In vitro assessment of drug-free and fenofibrate-containing lipid formulations using dispersion and digestion testing gives detailed insights into the likely fate of formulations in the intestine

(2013) Ravi Devraj et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

(2013) Hywel D. Williams et al.   PHARMACEUTICAL RESEARCH

Development of Solid SEDDS, V: Compaction and Drug Release Properties of Tablets Prepared by Adsorbing Lipid-Based Formulations onto Neusilin® US2

(2013) Suhas G. Gumaste et al.   PHARMACEUTICAL RESEARCH

Supersaturated Self-Nanoemulsifying Drug Delivery Systems (Super-SNEDDS) Enhance the Bioavailability of the Poorly Water-Soluble Drug Simvastatin in Dogs

(2012) Nicky Thomas et al.   AAPS Journal

Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations

(2012) Hywel D. Williams et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Lipid Digestion as a Trigger for Supersaturation: Evaluation of the Impact of Supersaturation Stabilization on the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems

(2012) Mette U. Anby et al.   MOLECULAR PHARMACEUTICS

Incomplete Desorption of Liquid Excipients Reduces the in Vitro and in Vivo Performance of Self-Emulsifying Drug Delivery Systems Solidified by Adsorption onto an Inorganic Mesoporous Carrier

(2012) Michiel Van Speybroeck et al.   MOLECULAR PHARMACEUTICS

Development of Solid Self-Emulsifying Drug Delivery System (SEDDS) I: Use of Poloxamer 188 as Both Solidifying and Emulsifying Agent for Lipids

(2012) Ankita V. Shah et al.   PHARMACEUTICAL RESEARCH

Effects of solid carriers on the crystalline properties, dissolution and bioavailability of flurbiprofen in solid self-nanoemulsifying drug delivery system (solid SNEDDS)

(2011) Jun Hyeok Kang et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Enhanced oral bioavailability of dexibuprofen by a novel solid Self-emulsifying drug delivery system (SEDDS)

(2009) Prabagar Balakrishnan et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Controlled poorly soluble drug release from solid self-microemulsifying formulations with high viscosity hydroxypropylmethylcellulose

(2008) Tao Yi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES