Advances and challenges in PBPK modeling – Analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base

Title
Advances and challenges in PBPK modeling – Analysis of factors contributing to the oral absorption of atazanavir, a poorly soluble weak base
Authors
Keywords
Physiologically based pharmacokinetic model, Pharmacokinetics, Atazanavir, Gastric emptying, Absorption, Dissolution, Supersaturation, Precipitation, Formulation development
Journal
Publisher
Elsevier BV
Online
2015-04-12
DOI
10.1016/j.ejpb.2015.03.031

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