In Vitro and In Situ Evaluation of pH-Dependence of Atazanavir Intestinal Permeability and Interactions with Acid-Reducing Agents

Pregnane X Receptor (PXR) at the Crossroads of Human Metabolism and Disease

(2013) Ioannis Koutsounas et al.   CURRENT DRUG METABOLISM

Pharmacokinetics and Pharmacodynamics of the Proton Pump Inhibitors

(2013) Jai Moo Shin et al.   Journal of Neurogastroenterology and Motility

Divalent Metals and pH Alter Raltegravir DispositionIn Vitro

(2012) Darren M. Moss et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Lipid Bilayer Properties Control Membrane Partitioning, Binding, and Transport of P-Glycoprotein Substrates

(2012) Adam T. Clay et al.   BIOCHEMISTRY

Role of Drug Efflux and Uptake Transporters in Atazanavir Intestinal Permeability and Drug-Drug Interactions

(2012) Olena Kis et al.   PHARMACEUTICAL RESEARCH

Effects of the H2-Receptor Antagonist Famotidine on the Pharmacokinetics of Atazanavir-Ritonavir With or Without Tenofovir in HIV-Infected Patients

(2011) Xiaodong Wang et al.   AIDS PATIENT CARE AND STDS

Application of Method Suitability for Drug Permeability Classification

(2010) Donna A. Volpe   AAPS Journal

The Use of Biorelevant Dissolution Media to Forecast the In Vivo Performance of a Drug

(2010) Sandra Klein   AAPS Journal

Predicting Drug Disposition via Application of a Biopharmaceutics Drug Disposition Classification System

(2010) Leslie Z. Benet   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer

(2010) Oliver Thews et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

(2010) W. F. W. Bierman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Effect of Low-Dose Omeprazole (20 mg Daily) on the Pharmacokinetics of Multiple-Dose Atazanavir With Ritonavir in Healthy Subjects

(2010) Li Zhu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

pH Dependence of Organic Anion-Transporting Polypeptide 2B1 in Caco-2 Cells: Potential Role in Antiretroviral Drug Oral Bioavailability and Drug-Drug Interactions

(2010) O. Kis et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Prediction of Solubility and Permeability Class Membership: Provisional BCS Classification of the World’s Top Oral Drugs

(2009) Arik Dahan et al.   AAPS Journal

P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir

(2009) Omar Janneh et al.   ANTIVIRAL THERAPY

The utility of rat jejunal permeability for biopharmaceutics classification system

(2009) Parvin Zakeri-Milani et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

The complexities of antiretroviral drug–drug interactions: role of ABC and SLC transporters

(2009) Olena Kis et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Closing the Gaps: A Full Scan of the Intestinal Expression of P-Glycoprotein, Breast Cancer Resistance Protein, and Multidrug Resistance-Associated Protein 2 in Male and Female Rats

(2008) C. MacLean et al.   DRUG METABOLISM AND DISPOSITION

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

(2008) Jason A. Zastre et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Segmental Dependent Transport of Low Permeability Compounds along the Small Intestine Due to P-Glycoprotein: The Role of Efflux Transport in the Oral Absorption of BCS Class III Drugs

(2008) Arik Dahan et al.   MOLECULAR PHARMACEUTICS