An overview of recent advancements in anticancer Pt(IV) prodrugs: New smart drug combinations, activation and delivery strategies
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Title
An overview of recent advancements in anticancer Pt(IV) prodrugs: New smart drug combinations, activation and delivery strategies
Authors
Keywords
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Journal
INORGANICA CHIMICA ACTA
Volume 548, Issue -, Pages 121388
Publisher
Elsevier BV
Online
2023-01-14
DOI
10.1016/j.ica.2023.121388
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Note: Only part of the references are listed.- Synthesis, Characterization and Photoactivation Studies on the Novel Pt(IV)-Based [Pt(OCOCH3)3(phterpy)] Complex
- (2023) Giovanni Canil et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Iodine Conjugated Pt(IV) Nanoparticles for Precise Chemotherapy with Iodine–Pt Guided Computed Tomography Imaging and Biotin-Mediated Tumor-Targeting
- (2022) Jie Yu et al. ACS Nano
- Comparison of irinotecan and oxaliplatin as the first-line therapies for metastatic colorectal cancer: a meta-analysis
- (2021) Sadayuki Kawai et al. BMC CANCER
- Anticancer effects against colorectal cancer models of chloro(triethylphosphine)gold(I) encapsulated in PLGA–PEG nanoparticles
- (2021) Alessio Menconi et al. BIOMETALS
- Are Pt(IV) Prodrugs That Release Combretastatin A4 True Multi-action Prodrugs?
- (2021) Claudia Schmidt et al. JOURNAL OF MEDICINAL CHEMISTRY
- Nanoparticle delivery of a triple-action Pt(iv) prodrug to overcome cisplatin resistance via synergistic effect
- (2021) Peng Xie et al. Biomaterials Science
- Combretastatins: An Overview of Structure, Probable Mechanisms of Action and Potential Applications
- (2020) Gökçe Şeker Karatoprak et al. MOLECULES
- Toward Multi-Targeted Platinum and Ruthenium Drugs—A New Paradigm in Cancer Drug Treatment Regimens?
- (2019) Reece G. Kenny et al. CHEMICAL REVIEWS
- A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton
- (2019) Hana Kostrhunova et al. JOURNAL OF MEDICINAL CHEMISTRY
- New designs for phototherapeutic transition metal complexes
- (2019) Peter J. Sadler et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cisplatin: The first metal based anticancer drug
- (2019) Sumit Ghosh BIOORGANIC CHEMISTRY
- Antiproliferative Activity of Pt(IV) Conjugates Containing the Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Ketoprofen and Naproxen †
- (2019) Mauro Ravera et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The cisplatin/serum albumin system: A reappraisal
- (2019) Lara Massai et al. INORGANICA CHIMICA ACTA
- Dual-targeting antitumor conjugates derived from platinum(IV) prodrugs and microtubule inhibitor CA-4 significantly exhibited potent ability to overcome cisplatin resistance
- (2019) Xiaochao Huang et al. BIOORGANIC CHEMISTRY
- The impact of whole human blood on the kinetic inertness of platinum(iv) prodrugs – an HPLC-ICP-MS study
- (2018) Sarah Theiner et al. DALTON TRANSACTIONS
- The cisplatin-based Pt(iv)-diclorofibrato multi-action anticancer prodrug exhibits excellent performances also under hypoxic conditions
- (2018) Elisabetta Gabano et al. DALTON TRANSACTIONS
- Pt(IV) complexes conjugating with chalcone analogue as inhibitors of microtubule polymerization exhibited selective inhibition in human cancer cells
- (2018) Xiaochao Huang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Pt(IV) prodrugs containing microtubule inhibitors displayed potent antitumor activity and ability to overcome cisplatin resistance
- (2018) Lingxue Li et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, characterization, and in vitro cytotoxicity of a Kiteplatin-Ibuprofen Pt(IV) prodrug
- (2018) Alessandra Curci et al. INORGANICA CHIMICA ACTA
- A Carrier-Free Nanostructure Based on Platinum(IV) Prodrug Enhances Cellular Uptake and Cytotoxicity
- (2018) Jingjie Tan et al. MOLECULAR PHARMACEUTICS
- A cancer vaccine-mediated postoperative immunotherapy for recurrent and metastatic tumors
- (2018) Tingting Wang et al. Nature Communications
- Light-driven transformable optical agent with adaptive functions for boosting cancer surgery outcomes
- (2018) Ji Qi et al. Nature Communications
- Bioconjugation with Maleimides: A useful Tool for Chemical Biology
- (2018) Pedro Miguel pimenta Gois et al. CHEMISTRY-A EUROPEAN JOURNAL
- Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands
- (2018) Xuejiao Li et al. BIOINORGANIC CHEMISTRY AND APPLICATIONS
- Comprehensive review on how platinum- and taxane-based chemotherapy of ovarian cancer affects biology of normal cells
- (2018) Justyna Mikuła-Pietrasik et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Metal Drugs and the Anticancer Immune Response
- (2018) Bernhard Englinger et al. CHEMICAL REVIEWS
- Multi-action Pt(IV) anticancer agents; do we understand how they work?
- (2018) Dan Gibson JOURNAL OF INORGANIC BIOCHEMISTRY
- May glutamine addiction drive the delivery of antitumor cisplatin-based Pt(IV) prodrugs?
- (2017) Mauro Ravera et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Folic Acid–Conjugated Pyropheophorbide a as the Photosensitizer Tested for In Vivo Targeted Photodynamic Therapy
- (2017) Jin Wang et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Nutrient acquisition strategies of mammalian cells
- (2017) Wilhelm Palm et al. NATURE
- Intracellular trafficking of new anticancer therapeutics: antibody–drug conjugates
- (2017) Muhammad Kalim et al. Drug Design Development and Therapy
- Light in diagnosis, therapy and surgery
- (2017) Seok Hyun Yun et al. Nature Biomedical Engineering
- Epigenetic and antitumor effects of platinum(IV)-octanoato conjugates
- (2017) Vojtech Novohradsky et al. Scientific Reports
- Tumor-Homing and Penetrating Peptide-Functionalized Photosensitizer-Conjugated PEG-PLA Nanoparticles for Chemo-Photodynamic Combination Therapy of Drug-Resistant Cancer
- (2016) Xingye Feng et al. ACS Applied Materials & Interfaces
- Activation of Platinum(IV) Prodrugs By Motexafin Gadolinium as a Redox Mediator
- (2016) Gregory Thiabaud et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action
- (2016) Xiaochao Huang et al. BIOCONJUGATE CHEMISTRY
- The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
- (2016) Timothy C. Johnstone et al. CHEMICAL REVIEWS
- Cisplatin versus carboplatin: comparative review of therapeutic management in solid malignancies
- (2016) Gwo Yaw Ho et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Platinum(iv) anticancer prodrugs – hypotheses and facts
- (2016) Dan Gibson DALTON TRANSACTIONS
- Toward overcoming cisplatin resistance via sterically hindered platinum(II) complexes
- (2016) Haiyan Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis, Evaluation, and Mechanism Study of Novel Indole-Chalcone Derivatives Exerting Effective Antitumor Activity Through Microtubule Destabilization in Vitro and in Vivo
- (2016) Jun Yan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Selective Photoactivation: From a Single Unit Monomer Insertion Reaction to Controlled Polymer Architectures
- (2016) Jiangtao Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Photodynamic Therapy Mediated by Nontoxic Core–Shell Nanoparticles Synergizes with Immune Checkpoint Blockade To Elicit Antitumor Immunity and Antimetastatic Effect on Breast Cancer
- (2016) Xiaopin Duan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Activation of Platinum(IV) Prodrugs by Cytochrome c and Characterization of the Protein Binding Sites
- (2016) Alessia Lasorsa et al. MOLECULAR PHARMACEUTICS
- Pt(iv) derivatives of cisplatin and oxaliplatin with phenylbutyrate axial ligands are potent cytotoxic agents that act by several mechanisms of action
- (2016) Raji Raveendran et al. Chemical Science
- Core-shell nanoscale coordination polymers combine chemotherapy and photodynamic therapy to potentiate checkpoint blockade cancer immunotherapy
- (2016) Chunbai He et al. Nature Communications
- New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells
- (2015) Vojtech Novohradsky et al. BIOCHEMICAL PHARMACOLOGY
- Cyclooxygenase inhibitors: From pharmacology to clinical read-outs
- (2015) Paola Patrignani et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Cytotoxicity profile of novel sterically hindered platinum(II) complexes with (1R,2R)-N1,N2-dibutyl-1,2-diaminocyclohexane
- (2015) Haiyan Zhang et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Recent Advances in Platinum (IV) Complex-Based Delivery Systems to Improve Platinum (II) Anticancer Therapy
- (2015) Xiaopeng Han et al. MEDICINAL RESEARCH REVIEWS
- Utilizing the electron transfer mechanism of chlorophyll a under light for controlled radical polymerization
- (2015) Sivaprakash Shanmugam et al. Chemical Science
- The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin
- (2014) Rakesh K. Pathak et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents
- (2014) Guangcheng Wang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- A novel naproxen derivative capable of displaying anti-cancer and anti-migratory properties against human breast cancer cells
- (2014) Jolly Deb et al. BMC CANCER
- Anti-tumor activity of non-steroidal anti-inflammatory drugs: Cyclooxygenase-independent targets
- (2014) Jason L. Liggett et al. CANCER LETTERS
- The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells
- (2014) Qinqin Cheng et al. CHEMICAL COMMUNICATIONS
- Conjugates of Cisplatin and Cyclooxygenase Inhibitors as Potent Antitumor Agents Overcoming Cisplatin Resistance
- (2014) Wilma Neumann et al. ChemMedChem
- Conjugation of Cisplatin Analogues and Cyclooxygenase Inhibitors to Overcome Cisplatin Resistance
- (2014) Wilma Neumann et al. ChemMedChem
- Recent developments in tubulin polymerization inhibitors: An overview
- (2014) Ramandeep Kaur et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Cisplatin in cancer therapy: Molecular mechanisms of action
- (2014) Shaloam Dasari et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Extending Serum Half-life of Albumin by Engineering Neonatal Fc Receptor (FcRn) Binding
- (2014) Jan Terje Andersen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands
- (2014) Vojtech Novohradsky et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Synthesis and Biological Evaluation of Furanoallocolchicinoids
- (2014) Yuliya V. Voitovich et al. JOURNAL OF MEDICINAL CHEMISTRY
- Synthesis and Biological Evaluation of Novel Millepachine Derivatives As a New Class of Tubulin Polymerization Inhibitors
- (2014) Zhuang Yang et al. JOURNAL OF MEDICINAL CHEMISTRY
- Understanding Intrinsically Irreversible, Non-Nernstian, Two-Electron Redox Processes: A Combined Experimental and Computational Study of the Electrochemical Activation of Platinum(IV) Antitumor Prodrugs
- (2014) Meghan C. McCormick et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cisplatin (CDDP) triggers cell death of MCF-7 cells following disruption of intracellular calcium ([Ca2+]i) homeostasis
- (2014) Nawaf Al-Taweel et al. JOURNAL OF TOXICOLOGICAL SCIENCES
- Unraveling the mysteries of serum albumin—more than just a serum protein
- (2014) Angelica M. Merlot et al. Frontiers in Physiology
- Physical energy for drug delivery; poration, concentration and activation
- (2013) Shanmugamurthy Lakshmanan et al. ADVANCED DRUG DELIVERY REVIEWS
- Synthesis and Characterization of Pt(IV) Fluorescein Conjugates to Investigate Pt(IV) Intracellular Transformations
- (2013) Ying Song et al. BIOCONJUGATE CHEMISTRY
- Maleimide-functionalised platinum(iv) complexes as a synthetic platform for targeted drug delivery
- (2013) Verena Pichler et al. CHEMICAL COMMUNICATIONS
- Conjugation of vitamin E analog α-TOS to Pt(iv) complexes for dual-targeting anticancer therapy
- (2013) Kogularamanan Suntharalingam et al. CHEMICAL COMMUNICATIONS
- New perspectives of valproic acid in clinical practice
- (2013) Lenka Činčárová et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Monofunctional and Higher-Valent Platinum Anticancer Agents
- (2013) Timothy C. Johnstone et al. INORGANIC CHEMISTRY
- Assessing the Dual Activity of a Chalcone–Phthalocyanine Conjugate: Design, Synthesis, and Antivascular and Photodynamic Properties
- (2013) Sinem Tuncel et al. MOLECULAR PHARMACEUTICS
- A Better Platinum-Based Anticancer Drug Yet to Come?
- (2012) Ulrike Olszewski et al. Anti-Cancer Agents in Medicinal Chemistry
- Facile Preparation of Mono-, Di- and Mixed-Carboxylato Platinum(IV) Complexes for Versatile Anticancer Prodrug Design
- (2012) Jenny Z. Zhang et al. CHEMISTRY-A EUROPEAN JOURNAL
- Novel tetracarboxylatoplatinum(iv) complexes as carboplatin prodrugs
- (2012) Hristo P. Varbanov et al. DALTON TRANSACTIONS
- Dinuclear Pt(ii)-bisphosphonate complexes: a scaffold for multinuclear or different oxidation state platinum drugs
- (2012) Sara Piccinonna et al. DALTON TRANSACTIONS
- What do we know about the reduction of Pt(IV) pro-drugs?
- (2012) Ezequiel Wexselblatt et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Discovery and Optimization of a Series of 2-Aryl-4-Amino-5-(3′,4′,5′-trimethoxybenzoyl)Thiazoles as Novel Anticancer Agents
- (2012) Romeo Romagnoli et al. JOURNAL OF MEDICINAL CHEMISTRY
- In Vitro Anticancer Activity of cis-Diammineplatinum(II) Complexes with β-Diketonate Leaving Group Ligands
- (2012) Justin J. Wilson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Theoretical Investigations and Density Functional Theory Based Quantitative Structure–Activity Relationships Model for Novel Cytotoxic Platinum(IV) Complexes
- (2012) Hristo P. Varbanov et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pyropheophorbide A and c(RGDyK) Comodified Chitosan-Wrapped Upconversion Nanoparticle for Targeted Near-Infrared Photodynamic Therapy
- (2012) Aiguo Zhou et al. MOLECULAR PHARMACEUTICS
- Whole cell microtubule analysis by flow cytometry
- (2011) Karen C. Morrison et al. ANALYTICAL BIOCHEMISTRY
- Anticancer Activity of Metal Complexes: Involvement of Redox Processes
- (2011) Ute Jungwirth et al. ANTIOXIDANTS & REDOX SIGNALING
- Pt(iv) analogs of oxaliplatin that do not follow the expected correlation between electrochemical reduction potential and rate of reduction by ascorbate
- (2011) Jenny Z. Zhang et al. CHEMICAL COMMUNICATIONS
- Trastuzumab Emtansine: A Unique Antibody-Drug Conjugate in Development for Human Epidermal Growth Factor Receptor 2-Positive Cancer
- (2011) P. M. LoRusso et al. CLINICAL CANCER RESEARCH
- Synthesis, Characterization, and Cytotoxicity of Platinum(IV) Carbamate Complexes
- (2011) Justin J. Wilson et al. INORGANIC CHEMISTRY
- Platinum resistance in breast and ovarian cancer cell lines
- (2011) Niels Eckstein JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Pt(IV) complexes as prodrugs for cisplatin
- (2011) Yi Shi et al. JOURNAL OF INORGANIC BIOCHEMISTRY
- Drugs that target dynamic microtubules: A new molecular perspective
- (2011) Richard A. Stanton et al. MEDICINAL RESEARCH REVIEWS
- Molecular mechanisms of cisplatin resistance
- (2011) L Galluzzi et al. ONCOGENE
- Albumin binding ligands and albumin conjugate uptake by cancer cells
- (2011) Eva Frei Diabetology & Metabolic Syndrome
- Cisplatin as an Anti-Tumor Drug: Cellular Mechanisms of Activity, Drug Resistance and Induced Side Effects
- (2011) Ana-Maria Florea et al. Cancers
- Synthesis and biological evaluation of indolyl chalcones as antitumor agents
- (2010) Dalip Kumar et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- New reduction pathways for ctc-[PtCl2(CH3CO2)2(NH3)(Am)] anticancer prodrugs
- (2010) Alina Nemirovski et al. CHEMICAL COMMUNICATIONS
- The role of porphyrin chemistry in tumor imaging and photodynamic therapy
- (2010) Manivannan Ethirajan et al. CHEMICAL SOCIETY REVIEWS
- Advances in Platinum Chemotherapeutics
- (2010) Benjamin W. Harper et al. CHEMISTRY-A EUROPEAN JOURNAL
- Redox metabolism and malignancy
- (2010) Christina L Grek et al. CURRENT OPINION IN PHARMACOLOGY
- The status of platinum anticancer drugs in the clinic and in clinical trials
- (2010) Nial J. Wheate et al. DALTON TRANSACTIONS
- Native albumin for targeted drug delivery
- (2010) Elena Neumann et al. Expert Opinion on Drug Delivery
- Studies on Cellular Accumulation of Satraplatin and Its Major Metabolite JM118 and Their Interactions with Glutathione
- (2010) Hana Kostrhunova et al. MOLECULAR PHARMACEUTICS
- Novel photosensitisers derived from pyropheophorbide-a: uptake by cells and photodynamic efficiency in vitro
- (2010) Ioanna Stamati et al. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
- Combretastatin-like chalcones as inhibitors of microtubule polymerization. Part 1: Synthesis and biological evaluation of antivascular activity
- (2009) Sylvie Ducki et al. BIOORGANIC & MEDICINAL CHEMISTRY
- A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2
- (2009) Genzo Iguchi et al. CANCER LETTERS
- Satraplatin: leading the new generation of oral platinum agents
- (2009) Ashish Bhargava et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Multinational, Double-Blind, Phase III Study of Prednisone and Either Satraplatin or Placebo in Patients With Castrate-Refractory Prostate Cancer Progressing After Prior Chemotherapy: The SPARC Trial
- (2009) Cora N. Sternberg et al. JOURNAL OF CLINICAL ONCOLOGY
- Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate
- (2009) Shanta Dhar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue
- (2008) H. Choy et al. CLINICAL CANCER RESEARCH
- Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles
- (2008) Felix Kratz JOURNAL OF CONTROLLED RELEASE
- Pt(II) Complexes of a Combretastatin A-4 Analogous Chalcone: Effects of Conjugation on Cytotoxicity, Tumor Specificity, and Long-Term Tumor Growth Suppression
- (2008) Rainer Schobert et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cisplatin nephrotoxicity: Mechanisms and renoprotective strategies
- (2008) N. Pabla et al. KIDNEY INTERNATIONAL
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