Recent Advances in Platinum (IV) Complex-Based Delivery Systems to Improve Platinum (II) Anticancer Therapy

Randomized, open label, phase III trial of figitumumab in combination with paclitaxel and carboplatin versus paclitaxel and carboplatin in patients with non-small cell lung cancer (NSCLC).

(2017) J. Jassem et al.   JOURNAL OF CLINICAL ONCOLOGY

Integrin-targeted delivery into cancer cells of a Pt(iv) pro-drug through conjugation to RGD-containing peptides

(2015) Anna Massaguer et al.   DALTON TRANSACTIONS

Dual-drug delivery of curcumin and platinum drugs in polymeric micelles enhances the synergistic effects: a double act for the treatment of multidrug-resistant cancer

(2015) Wei Scarano et al.   Biomaterials Science

Neuropilin-1-Targeted Gold Nanoparticles Enhance Therapeutic Efficacy of Platinum(IV) Drug for Prostate Cancer Treatment

(2014) Anil Kumar et al.   ACS Nano

Anticancer and DNA Binding Activities of Platinum (IV) Complexes; Importance of Leaving Group Departure Rate

(2014) Zahra Pouryasin et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Delivery of platinum(IV) drug to subcutaneous tumor and lung metastasis using bradykinin-potentiating peptide-decorated chitosan nanoparticles

(2014) Xin Wang et al.   BIOMATERIALS

Gelatin-encapsulated iron oxide nanoparticles for platinum (IV) prodrug delivery, enzyme-stimulated release and MRI

(2014) Ziyong Cheng et al.   BIOMATERIALS

A randomised, phase II trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent, partially platinum-sensitive ovarian cancer

(2014) R M Glasspool et al.   BRITISH JOURNAL OF CANCER

Phase 2 trial of erlotinib combined with cisplatin and radiotherapy in patients with locally advanced cervical cancer

(2014) Angelica Nogueira-Rodrigues et al.   CANCER

A targeted theranostic platinum(iv) prodrug containing a luminogen with aggregation-induced emission (AIE) characteristics for in situ monitoring of drug activation

(2014) Youyong Yuan et al.   CHEMICAL COMMUNICATIONS

Metal-based anticancer chemotherapeutic agents

(2014) Nafees Muhammad et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Pros and cons of bifunctional platinum(iv) antitumor prodrugs: two are (not always) better than one

(2014) Elisabetta Gabano et al.   DALTON TRANSACTIONS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A phase II trial of oxaliplatin, docetaxel, and bevacizumab as first-line therapy of advanced cancer of the ovary, peritoneum, and fallopian tube

(2014) Thomas J. Herzog et al.   GYNECOLOGIC ONCOLOGY

A New Entry to Asymmetric Platinum(IV) Complexes via Oxidative Chlorination

(2014) Mauro Ravera et al.   INORGANIC CHEMISTRY

Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application

(2014) Sarah Theiner et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Randomized, Phase III Trial of First-Line Figitumumab in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Patients With Advanced Non–Small-Cell Lung Cancer

(2014) Corey J. Langer et al.   JOURNAL OF CLINICAL ONCOLOGY

A clinical update of using albumin as a drug vehicle — A commentary

(2014) Felix Kratz   JOURNAL OF CONTROLLED RELEASE

Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands

(2014) Vojtech Novohradsky et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Platinum drugs binding to human serum albumin: Effect of non-steroidal anti-inflammatory drugs

(2014) Katarzyna Wiglusz et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY

Pt(IV) Prodrugs Designed to Bind Non-Covalently to Human Serum Albumin for Drug Delivery

(2014) Yao-Rong Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin

(2014) Longyan Liao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of EGFR-Targeted Nanoemulsion for Imaging and Novel Platinum Therapy of Ovarian Cancer

(2014) Srinivas Ganta et al.   PHARMACEUTICAL RESEARCH

Polymers with platinum drugs and other macromolecular metal complexes for cancer treatment

(2014) Manuela Callari et al.   PROGRESS IN POLYMER SCIENCE

Ratiometric delivery of cisplatin and doxorubicin using tumour-targeting carbon-nanotubes entrapping platinum(iv) prodrugs

(2014) Chee Fei Chin et al.   Chemical Science

Dual endogenous stimuli-responsive polyplex micelles as smart two-step delivery nanocarriers for deep tumor tissue penetration and combating drug resistance of cisplatin

(2014) Junjie Li et al.   Journal of Materials Chemistry B

Novel Pt-loaded layered double hydroxide nanoparticles for efficient and cancer-cell specific delivery of a cisplatin prodrug

(2014) Rong Ma et al.   Journal of Materials Chemistry B

Nanoscale Drug Delivery Platforms Overcome Platinum-Based Resistance in Cancer Cells Due to Abnormal Membrane Protein Trafficking

(2013) Xue Xue et al.   ACS Nano

Nanoparticle Encapsulation of Mitaplatin and the Effect Thereof on In Vivo Properties

(2013) Timothy C. Johnstone et al.   ACS Nano

Challenges for Metals in Medicine: How Nanotechnology May Help To Shape the Future

(2013) Nicolas P. E. Barry et al.   ACS Nano

Nanocarriers for delivery of platinum anticancer drugs

(2013) Hardeep S. Oberoi et al.   ADVANCED DRUG DELIVERY REVIEWS

Platinum Compounds: A Hope for Future Cancer Chemotherapy

(2013) Imran Ali et al.   Anti-Cancer Agents in Medicinal Chemistry

Phase II Trial of Loubo®(Lobaplatin) and Pemetrexed for Patients with Metastatic Breast Cancer not Responding to Anthracycline or Taxanes

(2013) Qian-Qian Deng et al.   Asian Pacific Journal of Cancer Prevention

ERK-mediated suppression of cilia in cisplatin-induced tubular cell apoptosis and acute kidney injury

(2013) Shixuan Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Folate Conjugation to Polymeric Micelles via Boronic Acid Ester to Deliver Platinum Drugs to Ovarian Cancer Cell Lines

(2013) Wei Scarano et al.   BIOMACROMOLECULES

Enhanced cytotoxicity to cancer cells by mitochondria-targeting MWCNTs containing platinum(IV) prodrug of cisplatin

(2013) Sia Lee Yoong et al.   BIOMATERIALS

Phase I drug-interaction study of effects of calcium and magnesium infusions on oxaliplatin pharmacokinetics and acute neurotoxicity in colorectal cancer patients

(2013) Catherine H Han et al.   BMC CANCER

Phase 1 study of cetuximab in combination with 5-fluorouracil, cisplatin, and radiotherapy in patients with locally advanced anal canal carcinoma

(2013) Luis O. Olivatto et al.   CANCER

A phase II study of intra-arterial cisplatin with concurrent radiation and erlotinib for locally advanced head and neck cancer

(2013) Krishna Rao et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Multicenter phase II study of capecitabine combined with nedaplatin for recurrent and metastatic nasopharyngeal carcinoma patients after failure of cisplatin-based chemotherapy

(2013) Pei-Jian Peng et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Oxidation of anticancer Pt(ii) complexes with monodentate phosphane ligands: towards stable but active Pt(iv) prodrugs

(2013) María Ángeles Medrano et al.   CHEMICAL COMMUNICATIONS

Conjugation of vitamin E analog α-TOS to Pt(iv) complexes for dual-targeting anticancer therapy

(2013) Kogularamanan Suntharalingam et al.   CHEMICAL COMMUNICATIONS

Synthetic Methods for the Preparation of Platinum Anticancer Complexes

(2013) Justin J. Wilson et al.   CHEMICAL REVIEWS

Phase II Study of Satraplatin and Prednisone in Patients With Metastatic Castration-Resistant Prostate Cancer: A Pharmacogenetic Assessment of Outcome and Toxicity

(2013) William D. Figg et al.   Clinical Genitourinary Cancer

Coordination polymer nanoparticles in medicine

(2013) F. Novio et al.   COORDINATION CHEMISTRY REVIEWS

Deep Penetration of Nanoparticulate Drug Delivery Systems into Tumors: Challenges and Solutions

(2013) L. Li et al.   CURRENT MEDICINAL CHEMISTRY

Targeted delivery of platinum-based anticancer complexes

(2013) Jennifer S Butler et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Liposomes, a promising strategy for clinical application of platinum derivatives

(2013) Sara Zalba et al.   Expert Opinion on Drug Delivery

Picoplatin pharmacokinetics and chemotherapy of non-small cell lung cancer

(2013) Gerhard Hamilton et al.   Expert Opinion on Drug Metabolism & Toxicology

Monomeric cisplatin complexes with glutathione: Coordination modes and binding affinities

(2013) Tamer Shoeib et al.   INORGANICA CHIMICA ACTA

Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

(2013) Rakesh K. Jain   JOURNAL OF CLINICAL ONCOLOGY

Phase III Randomized, Placebo-Controlled, Double-Blind Study of Intravenous Calcium and Magnesium to Prevent Oxaliplatin-Induced Sensory Neurotoxicity (N08CB/Alliance)

(2013) Charles L. Loprinzi et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeted co-delivery of docetaxel, cisplatin and herceptin by vitamin E TPGS-cisplatin prodrug nanoparticles for multimodality treatment of cancer

(2013) Yu Mi et al.   JOURNAL OF CONTROLLED RELEASE

Photosensitive Pt(IV)–azide prodrug-loaded nanoparticles exhibit controlled drug release and enhanced efficacy in vivo

(2013) Haihua Xiao et al.   JOURNAL OF CONTROLLED RELEASE

Influence of Equatorial and Axial Carboxylato Ligands on the Kinetic Inertness of Platinum(IV) Complexes in the Presence of Ascorbate and Cysteine and within DLD-1 Cancer Cells

(2013) Catherine K. J. Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis and In-Vitro Cytotoxicity of Novel Platinum (II) Complexes with Phthalate as the Leaving Group

(2013) Rajiv Sharma et al.   Letters in Drug Design & Discovery

Phase II study of oral S-1 and cisplatin with concurrent radiotherapy for locally advanced non-small-cell lung cancer

(2013) Kyoichi Kaira et al.   LUNG CANCER

A Core Cross-Linked Polymeric Micellar Platium(IV) Prodrug with Enhanced Anticancer Efficiency

(2013) Jie Hou et al.   MACROMOLECULAR BIOSCIENCE

Nonporous silica nanoparticles for nanomedicine application

(2013) Li Tang et al.   Nano Today

Macromolecular platinum-drugs based on statistical and block copolymer structures and their DNA binding ability

(2013) Khairil Juhanni Abd Karim et al.   Polymer Chemistry

Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug

(2013) X. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biodegradable Polysilsesquioxane Nanoparticles as Efficient Contrast Agents for Magnetic Resonance Imaging

(2013) Juan L. Vivero-Escoto et al.   Small

Phase II trial of bevacizumab and satraplatin in docetaxel-pretreated metastatic castrate-resistant prostate cancer

(2013) Ulka N. Vaishampayan et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Clinical developments of chemotherapeutic nanomedicines: polymers and liposomes for delivery of camptothecins and platinum (II) drugs

(2013) Heidi M. Kieler-Ferguson et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

A Polymer-(Tandem Drugs) Conjugate for Enhanced Cancer Treatment

(2013) Dongfang Zhou et al.   Advanced Healthcare Materials

Nedaplatin: a cisplatin derivative in cancer chemotherapy

(2013) Muneaki Shimada et al.   Cancer Management and Research

αVβ3 Integrin-Targeted PLGA-PEG Nanoparticles for Enhanced Anti-tumor Efficacy of a Pt(IV) Prodrug

(2012) Nora Graf et al.   ACS Nano

Layer-by-Layer Assembled Polypeptide Capsules for Platinum-Based Pro-Drug Delivery

(2012) Dongfang Zhou et al.   BIOCONJUGATE CHEMISTRY

A prodrug strategy to deliver cisplatin(IV) and paclitaxel in nanomicelles to improve efficacy and tolerance

(2012) Haihua Xiao et al.   BIOMATERIALS

Long-term bresults of radiotherapy combined with nedaplatin and 5-fluorouracil for postoperative loco-regional recurrent esophageal cancer: update on a phase II study

(2012) Keiichi Jingu et al.   BMC CANCER

A dual-targeting hybrid platinum(iv) prodrug for enhancing efficacy

(2012) Haihua Xiao et al.   CHEMICAL COMMUNICATIONS

Targeted polymeric therapeutic nanoparticles: design, development and clinical translation

(2012) Nazila Kamaly et al.   CHEMICAL SOCIETY REVIEWS

Targeting and delivery of platinum-based anticancer drugs

(2012) Xiaoyong Wang et al.   CHEMICAL SOCIETY REVIEWS

Novel tetracarboxylatoplatinum(iv) complexes as carboplatin prodrugs

(2012) Hristo P. Varbanov et al.   DALTON TRANSACTIONS

Synthesis, characterization and antiproliferative activity on mesothelioma cell lines of bis(carboxylato)platinum(iv) complexes based on picoplatin

(2012) Mauro Ravera et al.   DALTON TRANSACTIONS

Vitamin E TPGS prodrug micelles for hydrophilic drug delivery with neuroprotective effects

(2012) Yu Mi et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

What do we know about the reduction of Pt(IV) pro-drugs?

(2012) Ezequiel Wexselblatt et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The effect of sodium thiosulfate on the metabolism of cis-platin in human plasma in vitro

(2012) Melani Sooriyaarachchi et al.   Metallomics

Synthesis and in vitro cytotoxicity of cis,cis,trans-diamminedichloridodisuccinatoplatinum(iv)–peptide bioconjugates

(2012) Luca Gaviglio et al.   Metallomics

Conjugate of Pt(IV)–Histone Deacetylase Inhibitor as a Prodrug for Cancer Chemotherapy

(2012) Jun Yang et al.   MOLECULAR PHARMACEUTICS

Nanoparticles: the future for platinum drugs or a research red herring?

(2012) Nial J Wheate   Nanomedicine

The holistic 3M modality of drug delivery nanosystems for cancer therapy

(2012) Jin Sun et al.   Nanoscale

Subcellular targets of cisplatin cytotoxicity: An integrated view

(2012) Sandra M. Sancho-Martínez et al.   PHARMACOLOGY & THERAPEUTICS

Platinum(iv) prodrugs entrapped within multiwalled carbon nanotubes: Selective release by chemical reduction and hydrophobicity reversal

(2012) Jian Li et al.   Chemical Science

Platinum (IV) Pro-Drug Conjugated NaYF4:Yb3+/Er3+Nanoparticles for Targeted Drug Delivery and Up-Conversion Cell Imaging

(2012) Yunlu Dai et al.   Advanced Healthcare Materials

Multifunctional Pt(iv) pro-drug and its micellar platform: to kill two birds with one stone

(2012) Haiqin Song et al.   Journal of Materials Chemistry B

Theranostic Nanoshells: From Probe Design to Imaging and Treatment of Cancer

(2011) Rizia Bardhan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Platinum-(IV)-derivative satraplatin induced G2/M cell cycle perturbation via p53-p21waf1/cip1-independent pathway in human colorectal cancer cells

(2011) Murugan Kalimutho et al.   ACTA PHARMACOLOGICA SINICA

Platinum (IV)-coordinate polymers as intracellular reduction-responsive backbone-type conjugates for cancer drug delivery

(2011) Jun Yang et al.   BIOMATERIALS

Biodegradable polymer − cisplatin(IV) conjugate as a pro-drug of cisplatin(II)

(2011) Haihua Xiao et al.   BIOMATERIALS

Evaluation of a formula for individual dosage of nedaplatin based on renal function

(2011) Shinya Sato et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

A Decade of Advances in Cytotoxic Chemotherapy for Metastatic Colorectal Cancer

(2011) Amy S. Lucas et al.   Clinical Colorectal Cancer

Platinum Formulations as Anticancer Drugs Clinical and Pre-Clinical Studies

(2011) Nicholas P. Farrell   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Mono-carboxylated diaminedichloridoplatinum(iv) complexes – selective synthesis, characterization, and cytotoxicity

(2011) Verena Pichler et al.   DALTON TRANSACTIONS

Drug transporters of platinum-based anticancer agents and their clinical significance

(2011) Herman Burger et al.   DRUG RESISTANCE UPDATES

Clinical and pharmacokinetic evaluation of satraplatin

(2011) Gury Doshi et al.   Expert Opinion on Drug Metabolism & Toxicology

Synthesis, Characterization, and Cytotoxicity of Platinum(IV) Carbamate Complexes

(2011) Justin J. Wilson et al.   INORGANIC CHEMISTRY

A Novel Water-Soluble Heptaplatin Analogue with Improved Antitumor Activity and Reduced Toxicity

(2011) Weiping Liu et al.   INORGANIC CHEMISTRY

Pt(IV) complexes as prodrugs for cisplatin

(2011) Yi Shi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo

(2011) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A phase 1/1b study of satraplatin (JM-216) in combination with docetaxel in patients with advanced solid tumors and metastatic castrate-resistant prostate cancer

(2011) Jeremy Cetnar et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

A phase I study of the oral platinum agent satraplatin in sequential combination with capecitabine in the treatment of patients with advanced solid malignancies

(2010) Elisa Gallerani et al.   ACTA ONCOLOGICA

Imaging and drug delivery using theranostic nanoparticles

(2010) Siti M. Janib et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoparticle-based theranostic agents

(2010) Jin Xie et al.   ADVANCED DRUG DELIVERY REVIEWS

Platinum(II)−Dendrimer Conjugates: Synthesis and Investigations on Cytotoxicity, Cellular Distribution, Platinum Release, DNA, and Protein Binding

(2010) Timo Kapp et al.   BIOCONJUGATE CHEMISTRY

Core-Cross-Linked Micelles Synthesized by Clicking Bifunctional Pt(IV) Anticancer Drugs to Isocyanates

(2010) Hien T. T. Duong et al.   BIOMACROMOLECULES

Different Features of the DNA Binding Mode of Antitumorcis-Amminedichlorido(cyclohexylamine)platinum(II) (JM118) and Cisplatin in Vitro

(2010) Hana Kostrhunova et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The status of platinum anticancer drugs in the clinic and in clinical trials

(2010) Nial J. Wheate et al.   DALTON TRANSACTIONS

Intravenous Calcium and Magnesium for Oxaliplatin-Induced Sensory Neurotoxicity in Adjuvant Colon Cancer: NCCTG N04C7

(2010) Axel Grothey et al.   JOURNAL OF CLINICAL ONCOLOGY

Tuning of lipophilicity and cytotoxic potency by structural variation of anticancer platinum(IV) complexes

(2010) Michael R. Reithofer et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Comparative hydrolysis and plasma protein binding of cis-platin and carboplatin in human plasma in vitro

(2010) Melani Sooriyaarachchi et al.   Metallomics

Studies on Cellular Accumulation of Satraplatin and Its Major Metabolite JM118 and Their Interactions with Glutathione

(2010) Hana Kostrhunova et al.   MOLECULAR PHARMACEUTICS

Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy

(2010) N. Kolishetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymer nanocomposites based on functionalized carbon nanotubes

(2010) Nanda Gopal Sahoo et al.   PROGRESS IN POLYMER SCIENCE

Mechanisms of Cisplatin Nephrotoxicity

(2010) Ronald P. Miller et al.   Toxins

Polymer−Cisplatin Conjugate Nanoparticles for Acid-Responsive Drug Delivery

(2009) Santosh Aryal et al.   ACS Nano

The novel platinum(IV) complex LA-12 induces p53 and p53/47 responses that differ from the related drug, cisplatin

(2009) Roman Hrstka et al.   ANTI-CANCER DRUGS

Unusual DNA binding modes for metal anticancer complexes

(2009) Ana M. Pizarro et al.   BIOCHIMIE

Results of a phase II open-label, nonrandomized trial of oral satraplatin in patients with metastatic breast cancer

(2009) John W. Smith et al.   BREAST CANCER RESEARCH AND TREATMENT

Mechanistic insight into the cellular uptake and processing of cisplatin 30 years after its approval by FDA

(2009) Fabio Arnesano et al.   COORDINATION CHEMISTRY REVIEWS

Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting

(2009) Katherine S. Lovejoy et al.   DALTON TRANSACTIONS

Satraplatin: leading the new generation of oral platinum agents

(2009) Ashish Bhargava et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The effect of cellular environment and p53 status on the mode of action of the platinum derivative LA-12

(2009) Eva Roubalová et al.   INVESTIGATIONAL NEW DRUGS

Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate

(2009) Shanta Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Current Status and Future Prospects for Satraplatin, an Oral Platinum Analogue

(2008) H. Choy et al.   CLINICAL CANCER RESEARCH

Albumin as a drug carrier: Design of prodrugs, drug conjugates and nanoparticles

(2008) Felix Kratz   JOURNAL OF CONTROLLED RELEASE

Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles

(2008) S. Dhar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytotoxicity, mutagenicity, cellular uptake, DNA and glutathione interactions of lipophilic trans-platinum complexes tethered to 1-adamantylamine

(2007) Anna Halámiková et al.   JOURNAL OF INORGANIC BIOCHEMISTRY