Naphthalene Diimide-Functionalized Half-Sandwich Ru(II) Complexes as Mitochondria-Targeted Anticancer and Antimetastatic Agents

Synthesis, RNA-sequence and evaluation of anticancer efficacy of ruthenium(II) polypyridyl complexes toward HepG2 cells

(2023) Huiyan Hu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Mitochondria‐Targeting Phototheranostics by Aggregation‐Induced NIR‐II Emission Luminogens: Modulating Intramolecular Motion by Electron Acceptor Engineering for Multi‐Modal Synergistic Therapy

(2022) Tianfu Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

An osmium-peroxo complex for photoactive therapy of hypoxic tumors

(2022) Nong Lu et al.   Nature Communications

A supramolecular photosensitizer derived from an Arene-Ru(II) complex self-assembly for NIR activated photodynamic and photothermal therapy

(2022) Gang Xu et al.   Nature Communications

Synthesis, biological evaluation of novel iridium(III) complexes targeting mitochondria toward melanoma B16 cells

(2022) Yuhan Yuan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Disentangling the Structure–Activity Relationships of Naphthalene Diimides as Anticancer G-Quadruplex-Targeting Drugs

(2021) Chiara Platella et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antitumor Effect of Organometallic Half-Sandwich Ru(II)–Arene Complexes Bearing a Glutathione S-Transferase Inhibitor

(2021) Tianyu Han et al.   INORGANIC CHEMISTRY

What blocks more anticancer platinum complexes from experiment to clinic: Major problems and potential strategies from drug design perspectives

(2021) Kun Peng et al.   COORDINATION CHEMISTRY REVIEWS

Approaches towards understanding the mechanism-of-action of metallodrugs

(2021) Xiaolin Xiong et al.   COORDINATION CHEMISTRY REVIEWS

Synthesis and Structure of Arene Ru(II) N∧O-Chelating Complexes: In Vitro Cytotoxicity and Cancer Cell Death Mechanism

(2020) Sundarraman Balaji et al.   ORGANOMETALLICS

How promising is phototherapy for cancer?

(2020) Huayun Shi et al.   BRITISH JOURNAL OF CANCER

Dinuclear Organoruthenium Complexes Exhibiting Antiproliferative Activity through DNA Damage and a Reactive-Oxygen-Species-Mediated Endoplasmic Reticulum Stress Pathway

(2019) Jian Zhao et al.   INORGANIC CHEMISTRY

Targeted photoredox catalysis in cancer cells

(2019) Huaiyi Huang et al.   Nature Chemistry

Classification of Metal-Based Drugs according to Their Mechanisms of Action

(2019) Eszter Boros et al.   Chem

Effect of sulfonamidoethylenediamine substituents in RuII arene anticancer catalysts on transfer hydrogenation of coenzyme NAD+ by formate

(2018) Feng Chen et al.   DALTON TRANSACTIONS

Hypoxia-Targeting Organometallic Ru(II)–Arene Complexes with Enhanced Anticancer Activity in Hypoxic Cancer Cells

(2018) Jian Zhao et al.   INORGANIC CHEMISTRY

Transfer Hydrogenation and Antiproliferative Activity of Tethered Half-Sandwich Organoruthenium Catalysts

(2018) Feng Chen et al.   ORGANOMETALLICS

Anticancer Activity of Bifunctional Organometallic Ru(II) Arene Complexes Containing a 7-Hydroxycoumarin Group

(2018) Jian Zhao et al.   ORGANOMETALLICS

Imine-N-Heterocyclic Carbenes as Versatile Ligands in Ruthenium(II) p -Cymene Anticancer Complexes: A Structure-Activity Relationship Study

(2018) Yuliang Yang et al.   Chemistry-An Asian Journal

Novel and Versatile Imine-N-Heterocyclic Carbene Half-Sandwich Iridium(III) Complexes as Lysosome-Targeted Anticancer Agents

(2018) Yuliang Yang et al.   INORGANIC CHEMISTRY

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

(2018) Susan Monro et al.   CHEMICAL REVIEWS

Stimuli-Responsive Therapeutic Metallodrugs

(2018) Xiaohui Wang et al.   CHEMICAL REVIEWS

Ferrocenyl–Triphenyltin Complexes as Lysosome-Targeted Imaging and Anticancer Agents

(2018) Juanjuan Li et al.   INORGANIC CHEMISTRY

Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparities

(2016) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cytotoxicity of arene ruthenium metalla-rectangles incorporating bis-pyridyl diimide linkers

(2016) Ersin Orhan et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

A bimodal fluorescent and photocytotoxic naphthalene diimide for theranostic applications

(2016) Erica Salvati et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Core-Fluorinated Naphthalene Diimides: Synthesis, Characterization, and Application in n-Type Organic Field-Effect Transistors

(2016) Zhongyi Yuan et al.   ORGANIC LETTERS

Functionalization of Platinum Complexes for Biomedical Applications

(2015) Xiaoyong Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Antitumor and antiparasitic activity of novel ruthenium compounds with polycyclic aromatic ligands

(2015) Helena Guiset Miserachs et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

The Potent Oxidant Anticancer Activity of Organoiridium Catalysts

(2014) Zhe Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Metallodrugs in Medicinal Inorganic Chemistry

(2014) Katja Dralle Mjos et al.   CHEMICAL REVIEWS

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ambipolar charge-transport property for the D–A complex with naphthalene diimide motif

(2014) Xin Chen et al.   Journal of Materials Chemistry C

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Functionalized bipyridyl rhodium complex capable of electrode attachment for regeneration of NADH

(2013) Dharmalingam Sivanesan et al.   POLYHEDRON

Tumor microenvironment: a main actor in the metastasis process

(2012) Daniela Spano et al.   CLINICAL & EXPERIMENTAL METASTASIS

A Nonemissive Iridium(III) Complex That Specifically Lights-Up the Nuclei of Living Cells

(2011) Chunyan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Penetrative DNA intercalation and G-base selectivity of an organometallic tetrahydroanthracene RuII anticancer complex

(2010) Hong-Ke Liu et al.   Chemical Science

Redox Regulation of Cell Survival

(2008) Dunyaporn Trachootham et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanism of Cellular Uptake of a Ruthenium Polypyridyl Complex†

(2008) Cindy A. Puckett et al.   BIOCHEMISTRY

Catalytic organometallic anticancer complexes

(2008) S. J. Dougan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA