Tumor microenvironment: a main actor in the metastasis process

Proinflammatory S100 Proteins Regulate the Accumulation of Myeloid-Derived Suppressor Cells

(2014) P. Sinha et al.   JOURNAL OF IMMUNOLOGY

Myeloid-derived suppressor cells - their role in haemato-oncological malignancies and other cancers and possible implications for therapy

(2011) Tamar Tadmor et al.   BRITISH JOURNAL OF HAEMATOLOGY

Camouflage and sabotage: tumor escape from the immune system

(2011) Isabel Poschke et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs

(2011) Robert R. Langley et al.   INTERNATIONAL JOURNAL OF CANCER

Role of Fibulin-5 in Metastatic Organ Colonization

(2011) H. Devitt Moller et al.   MOLECULAR CANCER RESEARCH

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

(2011) Thordur Oskarsson et al.   NATURE MEDICINE

Elusive Identities and Overlapping Phenotypes of Proangiogenic Myeloid Cells in Tumors

(2010) Seth B. Coffelt et al.   AMERICAN JOURNAL OF PATHOLOGY

Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity

(2010) David G. DeNardo et al.   CANCER AND METASTASIS REVIEWS

Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity

(2010) Suzanne Ostrand-Rosenberg   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-Derived Suppressor Cells in Human Cancer

(2010) Srinivas Nagaraj et al.   CANCER JOURNAL

Lung Metastasis Fails in MMTV-PyMT Oncomice Lacking S100A4 Due to a T-Cell Deficiency in Primary Tumors

(2010) B. Grum-Schwensen et al.   CANCER RESEARCH

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Crosstalk between Mast Cells and Pancreatic Cancer Cells Contributes to Pancreatic Tumor Progression

(2010) M. J. Strouch et al.   CLINICAL CANCER RESEARCH

Molecular Pathways Linking Inflammation and Cancer

(2010) A. Mantovani   CURRENT MOLECULAR MEDICINE

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy

(2010) Pravin Mishra et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mast cells have a protumorigenic role in human thyroid cancer

(2010) R M Melillo et al.   ONCOGENE

Metastasis-Inducing S100A4 and RANTES Cooperate in Promoting Tumor Progression in Mice

(2010) Birgitte Forst et al.   PLoS One

S100A4 and Metastasis

(2009) Kjetil Boye et al.   AMERICAN JOURNAL OF PATHOLOGY

T-regulatory cell modulation: the future of cancer immunotherapy?

(2009) S Nizar et al.   BRITISH JOURNAL OF CANCER

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

The EGF/CSF-1 Paracrine Invasion Loop Can Be Triggered by Heregulin  1 and CXCL12

(2009) L. Hernandez et al.   CANCER RESEARCH

Mast Cells as Target in Cancer Therapy

(2009) Tom Kormelink et al.   CURRENT PHARMACEUTICAL DESIGN

Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein

(2009) Jörg Klingelhöfer et al.   FEBS Journal

Establishment of cancer cell lines from rat hepatocholangiocarcinoma and assessment of the role of granulocyte-colony stimulating factor and hepatocyte growth factor in their growth, motility and survival

(2009) Anna C. Piscaglia et al.   JOURNAL OF HEPATOLOGY

Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer

(2009) S. Ostrand-Rosenberg et al.   JOURNAL OF IMMUNOLOGY

Gene Expression Analysis of Macrophages That Facilitate Tumor Invasion Supports a Role for Wnt-Signaling in Mediating Their Activity in Primary Mammary Tumors

(2009) L. S. Ojalvo et al.   JOURNAL OF IMMUNOLOGY

Myeloid-Derived Suppressor Cells Down-Regulate L-Selectin Expression on CD4+ and CD8+ T Cells

(2009) E. M. Hanson et al.   JOURNAL OF IMMUNOLOGY

Mechanism Regulating Reactive Oxygen Species in Tumor-Induced Myeloid-Derived Suppressor Cells

(2009) C. A. Corzo et al.   JOURNAL OF IMMUNOLOGY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

(2009) Sunhwa Kim et al.   NATURE

A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth

(2009) Binzhi Qian et al.   PLoS One

G-CSF-initiated myeloid cell mobilization and angiogenesis mediate tumor refractoriness to anti-VEGF therapy in mouse models

(2009) F. Shojaei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?

(2009) Tamas A. Gonda et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

SCF-mediated mast cell infiltration and activation exacerbate the inflammation and immunosuppression in tumor microenvironment

(2008) B. Huang et al.   BLOOD

Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice

(2008) Y. Sawanobori et al.   BLOOD

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

(2008) Li Yang et al.   CANCER CELL

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Mast cells and tumour angiogenesis: New insight from experimental carcinogenesis

(2008) Enrico Crivellato et al.   CANCER LETTERS

Tumor Escape Mechanism Governed by Myeloid-Derived Suppressor Cells

(2008) S. Nagaraj et al.   CANCER RESEARCH

Myeloid-Derived Suppressor Cells Promote Cross-Tolerance in B-Cell Lymphoma by Expanding Regulatory T Cells

(2008) P. Serafini et al.   CANCER RESEARCH

Transforming Growth Factor  : Tumor Suppressor or Promoter? Are Host Immune Cells the Answer?

(2008) L. Yang et al.   CANCER RESEARCH

The Yin-Yang of tumor-associated macrophages in neoplastic progression and immune surveillance

(2008) Paola Allavena et al.   IMMUNOLOGICAL REVIEWS

Activation of NF-κB by extracellular S100A4: Analysis of signal transduction mechanisms and identification of target genes

(2008) Kjetil Boye et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophages define the invasive microenvironment in breast cancer

(2008) Jeffrey W. Pollard   JOURNAL OF LEUKOCYTE BIOLOGY

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

(2008) Sachie Hiratsuka et al.   NATURE CELL BIOLOGY