Lymphatic Invasion of Plakoglobin-Dependent Tumor Cell Clusters Drives Formation of Polyclonal Lung Metastases in Colon Cancer

Predicting 10-year survival after resection of colorectal liver metastases; an international study including biomarkers and perioperative treatment

(2022) Florian E. Buisman et al.   EUROPEAN JOURNAL OF CANCER

Genomic evolution and diverse models of systemic metastases in colorectal cancer

(2021) Hai-Ning Chen et al.   GUT

Collective metastasis: coordinating the multicellular voyage

(2021) Emma Wrenn et al.   CLINICAL & EXPERIMENTAL METASTASIS

Cooperation between melanoma cell states promotes metastasis through heterotypic cluster formation

(2021) Nathaniel R. Campbell et al.   DEVELOPMENTAL CELL

Hepatectomy Followed by mFOLFOX6 Versus Hepatectomy Alone for Liver-Only Metastatic Colorectal Cancer (JCOG0603): A Phase II or III Randomized Controlled Trial

(2021) Yukihide Kanemitsu et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-Lived Human Lymphatic Endothelial Cells to Study Lymphatic Biology and Lymphatic Vessel/Tumor Coculture in a 3D Microfluidic Model

(2021) Nicola Frenkel et al.   ACS Biomaterials-Science & Engineering

Mismatch Repair Status in Patient-Derived Colorectal Cancer Organoids Does Not Affect Intrinsic Tumor Cell Sensitivity to Systemic Therapy

(2021) Emre Küçükköse et al.   Cancers

Organoid models of gastrointestinal cancers in basic and translational research

(2020) Harry Cheuk Hay Lau et al.   Nature Reviews Gastroenterology & Hepatology

Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases

(2020) Johannes G. Reiter et al.   NATURE GENETICS

Genomic profiling of colorectal cancer with isolated lung metastasis

(2020) Nan Zhang et al.   Cancer Cell International

Modern therapeutic approaches for the treatment of malignant liver tumours

(2020) Henrik Petrowsky et al.   Nature Reviews Gastroenterology & Hepatology

Regulation of Collective Metastasis by Nanolumenal Signaling

(2020) Emma D. Wrenn et al.   CELL

Multi-color clonal tracking reveals intra-stage proliferative heterogeneity during mammary tumor progression

(2020) Stefanie Tiede et al.   ONCOGENE

Quantitative evidence for early metastatic seeding in colorectal cancer

(2019) Zheng Hu et al.   NATURE GENETICS

Collective cell migration and metastases induced by an epithelial-to-mesenchymal transition in Drosophila intestinal tumors

(2019) Kyra Campbell et al.   Nature Communications

Circulating tumor cells exit circulation while maintaining multicellularity, augmenting metastatic potential

(2019) Tyler A. Allen et al.   JOURNAL OF CELL SCIENCE

Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas

(2018) Olivier Zajac et al.   NATURE CELL BIOLOGY

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression

(2018) Arianna Fumagalli et al.   Nature Protocols

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

(2018) Ethel R. Pereira et al.   SCIENCE

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

(2018) M. Brown et al.   SCIENCE

Minimal functional driver gene heterogeneity among untreated metastases

(2018) Johannes G. Reiter et al.   SCIENCE

Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models

(2018) Xia Liu et al.   Cancer Discovery

Origins of lymphatic and distant metastases in human colorectal cancer

(2017) Kamila Naxerova et al.   SCIENCE

QuPath: Open source software for digital pathology image analysis

(2017) Peter Bankhead et al.   Scientific Reports

Metastatic Spread Emerging From Liver Metastases of Colorectal Cancer

(2016) Nuh N. Rahbari et al.   ANNALS OF SURGERY

A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

(2016) Masayuki Fujii et al.   Cell Stem Cell

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

(2016) Kevin J. Cheung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A collective route to metastasis: Seeding by tumor cell clusters

(2016) K. J. Cheung et al.   SCIENCE

Patterns of metastasis in colon and rectal cancer

(2016) Matias Riihimäki et al.   Scientific Reports

The consensus molecular subtypes of colorectal cancer

(2015) Justin Guinney et al.   NATURE MEDICINE

Pancreatic Cancer Metastases Harbor Evidence of Polyclonality

(2015) R. Maddipati et al.   Cancer Discovery

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

(2014) Nicola Aceto et al.   CELL

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

(2012) Alexandre Calon et al.   CANCER CELL

RGB marking with lentiviral vectors for multicolor clonal cell tracking

(2012) Kristoffer Weber et al.   Nature Protocols

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Epidemiology, management and prognosis of colorectal cancer with lung metastases: a 30-year population-based study

(2010) E. Mitry et al.   GUT

Circulating tumour cells during laparoscopic and open surgery for primary colonic cancer in portal and peripheral blood

(2009) J. Wind et al.   EJSO

Unique Localization of Circulating Tumor Cells in Patients With Hepatic Metastases

(2009) Long R. Jiao et al.   JOURNAL OF CLINICAL ONCOLOGY

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer

(2009) Chia Huey Ooi et al.   PLoS Genetics

How Uncommon are Isolated Lung Metastases in Colorectal Cancer? A Review from Database of 754 Patients Over 4 Years

(2008) Ker Kan Tan et al.   JOURNAL OF GASTROINTESTINAL SURGERY