Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice

Lymph node metastases can invade local blood vessels, exit the node, and colonize distant organs in mice

(2018) Ethel R. Pereira et al.   SCIENCE

Origins of lymphatic and distant metastases in human colorectal cancer

(2017) Kamila Naxerova et al.   SCIENCE

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels

(2016) Erica Russo et al.   Cell Reports

Regional Nodal Irradiation in Early-Stage Breast Cancer

(2015) Timothy J. Whelan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Internal Mammary and Medial Supraclavicular Irradiation in Breast Cancer

(2015) Philip M. Poortmans et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sentinel lymph node metastases in cancer: Causes, detection and their role in disease progression

(2015) S.D. Nathanson et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Role of lymphatic vasculature in regional and distant metastases

(2014) Simona Podgrabinska et al.   MICROVASCULAR RESEARCH

Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

(2013) Kevin J. Cheung et al.   CELL

Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses

(2013) Suvendu Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Significance and Mechanism of Lymph Node Metastasis in Cancer Progression

(2011) Kenji Kawada et al.   CANCER RESEARCH

Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10 801 women in 17 randomised trials

(2011)   LANCET

Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration

(2011) Asolina Braun et al.   NATURE IMMUNOLOGY

The lymphatic vasculature in disease

(2011) Kari Alitalo   NATURE MEDICINE

Interaction of tumor cells and lymphatic vessels in cancer progression

(2011) A Alitalo et al.   ONCOGENE

A Perspective on Cancer Cell Metastasis

(2011) C. L. Chaffer et al.   SCIENCE

The Role of Lymph Node Metastasis in the Systemic Dissemination of Breast Cancer

(2009) S. David Nathanson et al.   ANNALS OF SURGICAL ONCOLOGY

Suppression of Prostate Cancer Nodal and Systemic Metastasis by Blockade of the Lymphangiogenic Axis

(2008) J. B. Burton et al.   CANCER RESEARCH