Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension

Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension

(2023) Marius M. Hoeper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Using the Plasma Proteome for Risk Stratifying Patients with Pulmonary Arterial Hypertension

(2022) Christopher J Rhodes et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Mining the Plasma Proteome for Insights into the Molecular Pathology of Pulmonary Arterial Hypertension

(2022) Lars Harbaum et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

New Mutations and Pathogenesis of Pulmonary Hypertension: Progress and Puzzles in Disease Pathogenesis

(2022) Micheala A. Aldred et al.   CIRCULATION RESEARCH

Sotatercept analog suppresses inflammation to reverse experimental pulmonary arterial hypertension

(2022) Sachindra R. Joshi et al.   Scientific Reports

2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension

(2022) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Sotatercept for the treatment of pulmonary arterial hypertension: PULSAR open-label extension

(2022) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Cytokines as Prognostic Biomarkers in Pulmonary Arterial Hypertension

(2022) Athénaïs Boucly et al.   EUROPEAN RESPIRATORY JOURNAL

The evolving landscape of pulmonary arterial hypertension clinical trials

(2022) Jason Weatherald et al.   LANCET

Serum and Pulmonary Uric Acid in Pulmonary Arterial Hypertension

(2021) Laurent Savale et al.   EUROPEAN RESPIRATORY JOURNAL

Sotatercept for the Treatment of Pulmonary Arterial Hypertension

(2021) Marc Humbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension

(2021) Gusty R. T. Ryanto et al.   Nature Communications

COMPERA 2.0: A refined 4-strata risk assessment model for pulmonary arterial hypertension

(2021) Marius M. Hoeper et al.   EUROPEAN RESPIRATORY JOURNAL

External validation of a refined 4-strata risk assessment score from the French pulmonary hypertension Registry

(2021) Athénaïs Boucly et al.   EUROPEAN RESPIRATORY JOURNAL

Biological heterogeneity in idiopathic pulmonary arterial hypertension identified through unsupervised transcriptomic profiling of whole blood

(2021) Sokratis Kariotis et al.   Nature Communications

ACTRIIA-Fc rebalances activin/GDF versus BMP signaling in pulmonary hypertension

(2020) Lai-Ming Yung et al.   Science Translational Medicine

Targeting Transforming Growth Factor Beta Receptors in Pulmonary Hypertension

(2020) Christophe Guignabert et al.   EUROPEAN RESPIRATORY JOURNAL

Development and Validation of an Abridged Version of the REVEAL 2.0 Risk Score Calculator, REVEAL Lite 2, for use in Patients with Pulmonary Arterial Hypertension

(2020) Raymond L. Benza et al.   CHEST

Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension

(2019) Andrew J Sweatt et al.   CIRCULATION RESEARCH

Use of red cell distribution width in a population at high risk for pulmonary hypertension

(2019) Laura A. Petrauskas et al.   RESPIRATORY MEDICINE

Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator

(2019) Alice Huertas et al.   CARDIOVASCULAR RESEARCH

Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives

(2018) Marc Humbert et al.   EUROPEAN RESPIRATORY JOURNAL

Haemodynamic definitions and updated clinical classification of pulmonary hypertension

(2018) Gérald Simonneau et al.   EUROPEAN RESPIRATORY JOURNAL

A comprehensive risk stratification at early follow-up determines prognosis in pulmonary arterial hypertension

(2017) David Kylhammar et al.   EUROPEAN HEART JOURNAL

Management and long-term outcomes of sarcoidosis-associated pulmonary hypertension

(2017) Athénaïs Boucly et al.   EUROPEAN RESPIRATORY JOURNAL

Mortality in pulmonary arterial hypertension: prediction by the 2015 European pulmonary hypertension guidelines risk stratification model

(2017) Marius M. Hoeper et al.   EUROPEAN RESPIRATORY JOURNAL

Risk assessment, prognosis and guideline implementation in pulmonary arterial hypertension

(2017) Athénaïs Boucly et al.   EUROPEAN RESPIRATORY JOURNAL

A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension

(2016) Lai-Ming Yung et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Five-Year Outcomes of Patients Enrolled in the REVEAL Registry

(2015) Harrison W. Farber et al.   CHEST

Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension

(2014) Nicolas Ricard et al.   CIRCULATION

The REVEAL Registry Risk Score Calculator in Patients Newly Diagnosed With Pulmonary Arterial Hypertension

(2011) Raymond L. Benza et al.   CHEST

Elevated Levels of Inflammatory Cytokines Predict Survival in Idiopathic and Familial Pulmonary Arterial Hypertension

(2010) Elaine Soon et al.   CIRCULATION

Survival in Patients With Idiopathic, Familial, and Anorexigen-Associated Pulmonary Arterial Hypertension in the Modern Management Era

(2010) Marc Humbert et al.   CIRCULATION

Elevated levels of activin A in clinical and experimental pulmonary hypertension

(2009) Arne Yndestad et al.   JOURNAL OF APPLIED PHYSIOLOGY

Growth Differentiation Factor-15 in Idiopathic Pulmonary Arterial Hypertension

(2008) Nils Nickel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Association of Serum Creatinine With Abnormal Hemodynamics and Mortality in Pulmonary Arterial Hypertension

(2008) Sanjiv J. Shah et al.   CIRCULATION