Positron Emission Tomography with [18F]‐DPA‐714 Unveils a Smoldering Component in Most Multiple Sclerosis Lesions which Drives Disease Progression

A New Advanced MRI Biomarker for Remyelinated Lesions in Multiple Sclerosis

(2022) Reza Rahmanzadeh et al.   ANNALS OF NEUROLOGY

Microglia in multiple sclerosis: Protectors turn destroyers

(2022) V. Wee Yong   NEURON

Imaging Characteristics of Choroid Plexuses in Presymptomatic Multiple Sclerosis

(2022) Vito A.G. Ricigliano et al.   Neurology-Neuroimmunology & Neuroinflammation

Structural and Clinical Correlates of a Periventricular Gradient of Neuroinflammation in Multiple Sclerosis

(2021) Emilie Poirion et al.   NEUROLOGY

Activated microglia do not increase 18 kDa translocator protein ( TSPO ) expression in the multiple sclerosis brain

(2021) Erik Nutma et al.   GLIA

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

(2021) Martina Absinta et al.   NATURE

Positron emission tomography in multiple sclerosis — straight to the target

(2021) Benedetta Bodini et al.   Nature Reviews Neurology

Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans

(2021) Vinzenz Fleischer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Individual mapping of innate immune cell activation is a candidate marker of patient-specific trajectories of disability worsening in Multiple Sclerosis

(2020) Benedetta Bodini et al.   JOURNAL OF NUCLEAR MEDICINE

Lesion stage-dependent causes for impaired remyelination in MS

(2020) Katharina Heß et al.   ACTA NEUROPATHOLOGICA

Specialized Pro-Resolving Lipid Mediators: Emerging Therapeutic Candidates for Multiple Sclerosis

(2020) Insha Zahoor et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Analysis of 2 Randomized Clinical Trials

(2020) Ludwig Kappos et al.   JAMA Neurology

Extrinsic immune cell-derived, but not intrinsic oligodendroglial factors contribute to oligodendroglial differentiation block in multiple sclerosis

(2020) Laura Starost et al.   ACTA NEUROPATHOLOGICA

Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis

(2020) Marcus Sucksdorff et al.   BRAIN

In vivo imaging of chronic active lesions in multiple sclerosis

(2020) Alberto Calvi et al.   Multiple Sclerosis Journal

Altered human oligodendrocyte heterogeneity in multiple sclerosis

(2019) Sarah Jäkel et al.   NATURE

Neuronal vulnerability and multilineage diversity in multiple sclerosis

(2019) Lucas Schirmer et al.   NATURE

The pro-remyelination properties of microglia in the central nervous system

(2019) Amy F. Lloyd et al.   Nature Reviews Neurology

Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis

(2019) Colm Elliott et al.   BRAIN

Cortical atrophy accelerates as cognitive decline worsens in multiple sclerosis

(2019) Anand J.C. Eijlers et al.   NEUROLOGY

Association of Chronic Active Multiple Sclerosis Lesions With Disability In Vivo

(2019) Martina Absinta et al.   JAMA Neurology

A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis

(2019) Erik Nutma et al.   BRAIN

Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis

(2018) Sabina Luchetti et al.   ACTA NEUROPATHOLOGICA

An Automated Statistical Technique for Counting Distinct Multiple Sclerosis Lesions

(2018) J.D. Dworkin et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Cognition in multiple sclerosis

(2018) James F. Sumowski et al.   NEUROLOGY

Quantitative susceptibility mapping identifies inflammation in a subset of chronic multiple sclerosis lesions

(2018) Ulrike W Kaunzner et al.   BRAIN

Slowly expanding/evolving lesions as a magnetic resonance imaging marker of chronic active multiple sclerosis lesions

(2018) Colm Elliott et al.   Multiple Sclerosis Journal

Validation of an automatic reference region extraction for the quantification of [18F]DPA-714 in dynamic brain PET studies

(2017) Daniel García-Lorenzo et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

11 C-PBR28 and 18 F-PBR111 Detect White Matter Inflammatory Heterogeneity in Multiple Sclerosis

(2017) Gourab Datta et al.   JOURNAL OF NUCLEAR MEDICINE

Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis

(2017) Ralph HB Benedict et al.   Multiple Sclerosis Journal

Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis

(2017) Ralph HB Benedict et al.   Multiple Sclerosis Journal

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging

(2016) Assunta Dal-Bianco et al.   ACTA NEUROPATHOLOGICA

An updated histological classification system for multiple sclerosis lesions

(2016) Tanja Kuhlmann et al.   ACTA NEUROPATHOLOGICA

Neuroinflammatory component of gray matter pathology in multiple sclerosis

(2016) Elena Herranz et al.   ANNALS OF NEUROLOGY

Persistent 7-tesla phase rim predicts poor outcome in new multiple sclerosis patient lesions

(2016) Martina Absinta et al.   JOURNAL OF CLINICAL INVESTIGATION

The EDSS-Plus, an improved endpoint for disability progression in secondary progressive multiple sclerosis

(2016) Diego Cadavid et al.   Multiple Sclerosis Journal

The EDSS-Plus, an improved endpoint for disability progression in secondary progressive multiple sclerosis

(2016) Diego Cadavid et al.   Multiple Sclerosis Journal

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque

(2015) Josa M. Frischer et al.   ANNALS OF NEUROLOGY

In Vivo Assessment of Brain White Matter Inflammation in Multiple Sclerosis with 18F-PBR111 PET

(2014) A. Colasanti et al.   JOURNAL OF NUCLEAR MEDICINE

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus

(2013) Michal Schwartz et al.   EMBO JOURNAL

Jacobian integration method increases the statistical power to measure gray matter atrophy in multiple sclerosis

(2013) Kunio Nakamura et al.   NeuroImage-Clinical

An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

(2011) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Quantitative in vivo magnetic resonance imaging of multiple sclerosis at 7 Tesla with sensitivity to iron

(2008) Kathryn E. Hammond et al.   ANNALS OF NEUROLOGY